Results 71 to 80 of about 16,055,310 (231)

Characterization of Diverse Subvariants of the Meningococcal Factor H (fH) Binding Protein for Their Ability To Bind fH, To Mediate Serum Resistance, and To Induce Bactericidal Antibodies

, 2011
Neisseria meningitidis is a commensal of the human nasopharynx but is also a major cause of septicemia and meningitis. The meningococcal factor H binding protein (fHbp) binds human factor H (fH), enabling down-regulation of complement activation on the ...
Comanducci, Maurizio, Brunella Brunelli, Barbara Brogioni, Beatrice Aricó, Giuliani, Marzia M, Savino, Silvana, Scarselli, Maria, Maurizio Comanducci, Marzia M. Giuliani, Brunelli, Brunella, Marchi, Sara, Bambini, Stefania, Brogioni, Barbara, Emmanuelle Palumbo, Alessandro Muzzi, Mariagrazia Pizza, Silvana Savino, Palumbo, Emmanuelle, Rappuoli, Rino, Maria Scarselli, Kate L. Seib, Rino Rappuoli, Stefania Bambini, Pizza, Mariagrazia, Sara Marchi, Arie van der Ende, Seib, Kate L, Muzzi, Alessandro, Federica DiMarcello, Arico, Beatrice, DiMarcello, Federica, Van der Ende, Arie   +31 more
core   +1 more source

Sub‐nm2 Ferroelectric Domains via Charged 180° Walls in ZrO2

Advanced Materials, EarlyView.
Ferroelectric ZrO2${\rm ZrO}_2$ thin films host closely spaced charged 180∘$^{\circ }$ domain walls that vertically compress polar domains beyond their lateral half‐unit‐cell limit. These head‐to‐head and tail‐to‐tail walls show distinct bulk‐like structures, natural oxygen‐mediated stabilization, and highly asymmetric mobility, highlighting new ...
Nashrah Afroze, Hamoon Fahrvandi, Guodong Ren, Pawan Kumar, Christopher Nelson, Sarah Lombardo, Mengkun Tian, Ping‐Che Lee, Jiayi Chen, Manifa Noor, Kisung Chae, Sanghyun Kang, Prasanna Venkat Ravindran, Matthew Bergschneider, Gwan Yeong Jung, Pravan Omprakash, Gardy K. Ligonde, Nujhat Tasneem, Dina Triyoso, Steven Consiglio, Kanda Tapily, Robert Clark, Gert Leusink, Jayakanth Ravichandran, Shimeng Yu, Andrew R Lupini, Andrew C Kummel, Kyeongjae Cho, Duk‐Hyun Choe, Nazanin Bassiri‐Gharb, Josh Kacher, Rohan Mishra, Jun Hee Lee, Asif Khan   +33 more
wiley   +1 more source

Low Resistance Interphase Formation at the PEO‐LiTFSI|LGPS Interface in Lithium Solid‐State Batteries

Advanced Materials Interfaces, EarlyView.
Interfacial charge transfer and low‐resistance interphase formation between PEO‐based polymer and Li10GeP2S12 solid electrolytes are investigated using multi‐electrode impedance spectroscopy and advanced analytical techniques such as XPS and ToF‐SIMS.
Ujjawal Sigar, Timo Weintraut, Sebastian L. Benz, Semih Engün, Sascha Kremer, Anja Henss, Felix H. Richter   +6 more
wiley   +1 more source

Tuning the Functionality by Splicing: Factor H and Its Alternative Splice Variant FHL-1 Share a Gene but Not All Functions

Frontiers in Immunology, 2020
The alternative pathway regulator Factor H-like protein 1 (FHL-1) is composed of the first 7 N-terminal complement control protein domains of Factor H (FH) and protects host surfaces from uncontrolled complement attack.
Marco Mannes, Arthur Dopler, Markus Huber-Lang, Christoph Q. Schmidt   +3 more
doaj   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

Complement factor H [PDF]

, 2012
Complement factor H (fH) is a single chain plasma glycoprotein (approximately 150 kDa in size), with 20 domains termed complement control protein (CCP) domains or short consensus repeats (SCR).
Dinasarapu, Ashok Reddy, Jozsi, Mihaly, Subramaniam, Shankar, Chandrasekhar, Anjana   +3 more
core   +1 more source

Flexible Pressure Sensor With Co‐Optimized Sensitivity and Linearity Based on Gradient Toroidal Microstructures

Advanced Materials Technologies, EarlyView.
A flexible piezoresistive pressure sensor with gradient toroidal CNT/PDMS microstructures is reported. The hierarchical geometry enables sequential electrode contact, achieving a sensitivity of 256.20 kPa−1 and linear response (R2 = 0.99) over 0–1000 kPa.
Rongmei Wang, Ruolin Liu, Ming Lei, Yifan Liu, Fengming Hu, Bing Ji, Chao Peng, Jianyi Luo, Bingpu Zhou   +8 more
wiley   +1 more source

Bioinspired Adaptive Artificial Cilia With Tunable Sensitivity and Dynamic Range for Airflow Monitoring in the Central Airway

Advanced Materials Technologies, EarlyView.
A magnetically reconfigurable airflow sensor integrated with an airway stent enables tunable sensitivity and dynamic sensing range. Airflow‐induced cantilever deformation generates resistance changes, while an external magnetic field modulates sensor stiffness, enhancing sensitivity at low airflow velocities and extending the sensing range at higher ...
Darren Wang, Ruijian Ge, Shuda Dong, Zhongming Lyu, Yusheng Wang, Nicholas Strymish, Hanwen Fan, Fabien Maldonado, Caitlin T. Demarest, Yuxiao Zhou, Xiaoguang Dong   +10 more
wiley   +1 more source

Intracellular complement Factor H promotes tumor progression through modulation of cell cycle and actin cytoskeleton

Communications Biology
Overexpression of complement genes in the tumor microenvironment, including Factor H (FH), is a strong predictor of poor prognosis in multiple cancers. Its canonical functions in the bloodborne complement cascade, though, cannot explain this prognostic ...
Mikel Rezola Artero, Andrea Minery, Margot Revel, Angela Armento, Mohamed-Ali Jarboui, Idris Boudhabhay, Marina de Castro Deus, Alessandra Zarantonello, Emma Fleury, Lou Segarra, Alaeddine Redissi, Nicolas S. Merle, Marie-Agnes Dragon-Durey, Catherine Monnot, Catherine Sautes-Fridman, Jordan D. Dimitrov, Wolf Herman Fridman, Marius Ueffing, Lubka T. Roumenina   +18 more
doaj   +1 more source

Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance

Frontiers in Immunology
Factor H (FH) is a crucial complement regulator that prevents complement-mediated injury to healthy cells and tissues. This regulatory function can be disrupted by Factor H autoantibodies (FHAA), which then leads to diseases such as atypical hemolytic ...
Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez   +12 more
doaj   +1 more source