Results 51 to 60 of about 306,625 (170)

Anti-Factor H Antibodies in Egyptian Children with Hemolytic Uremic Syndrome

open access: yesInternational Journal of Nephrology, 2021
Background. Atypical hemolytic uremic syndrome (aHUS) is an important cause of acute kidney injury in children. It is primarily caused by dysregulation of the complement alternative pathway due to genetic mutations, mainly in complement factor H genes ...
Shereen Shawky   +7 more
doaj   +1 more source

Contribución de variantes funcionales y cuantitativas del Factor H y las proteínas FHRs (Factor H-Related proteins) del Complemento en patología renal

open access: yesNefrología, 2022
Resumen: El sistema del Complemento protege al organismo frente a procesos infecciosos, tumorales y autoinmunes, y requiere una regulación muy estricta para evitar una activación excesiva o inespecífica.
Irene Gómez Delgado   +1 more
doaj   +1 more source

Factor H Cleavage by the Treponema denticola Protease Dentilisin: Understanding the Pathogenesis of Periodontal Disease [PDF]

open access: yes, 2013
Periodontal disease is an infectious condition that results in the inflammation and gradual degradation of gum tissue and alveolar bone. Caused by plaque deposits on teeth that harden into tartar to inflame gum tissue, the condition is highly pervasive ...
Aggarwal, Sahil
core   +1 more source

Properdin has an ascendancy over factor H regulation in complement-mediated renal tubular damage [PDF]

open access: yes, 2014
BACKGROUND: Urinary (U)-complement components have been detected in patients with proteinuric renal diseases, and complement activation via the alternative pathway (AP) is believed to play a role in renal tubular damage.
Atsuko Hisada   +10 more
core   +1 more source

Delivery of CR2-fH Using AAV Vector Therapy as Treatment Strategy in the Mouse Model of Choroidal Neovascularization

open access: yesMolecular Therapy: Methods & Clinical Development, 2018
Complement activation plays a significant role in age-related macular degeneration (AMD) pathogenesis, and polymorphisms interfering with factor H (fH) function, a complement alternative pathway (AP) inhibitor, are associated with increased AMD risk.
Gloriane Schnabolk   +7 more
doaj   +1 more source

Contribution of functional and quantitative genetic variants of Complement Factor H and Factor H-Related (FHR) proteins on renal pathology

open access: yesNefrología (English Edition), 2022
The complement system is a first line of defence against infectious, tumoral or autoimmune processes, and it is constitutively regulated to avoid excessive or unspecific activation. Factor H (FH), a most relevant complement regulator, controls complement
Irene Gómez Delgado   +1 more
doaj   +1 more source

CFHTLenS: Weak lensing constraints on the ellipticity of galaxy-scale matter haloes and the galaxy-halo misalignment [PDF]

open access: yes, 2015
We present weak lensing constraints on the ellipticity of galaxy-scale matter haloes and the galaxy-halo misalignment. Using data from the Canada-France-Hawaii Telescope Lensing Survey (CFHTLenS), we measure the weighted-average ratio of the aligned ...
Bett, Philip   +18 more
core   +4 more sources

A Neighborhood Condition for Fractional ID-[A, B]-Factor-Critical Graphs

open access: yesDiscussiones Mathematicae Graph Theory, 2016
Let G be a graph of order n, and let a and b be two integers with 1 ≤ a ≤ b. Let h : E(G) → [0, 1] be a function. If a ≤ ∑e∋x h(e) ≤ b holds for any x ∈ V (G), then we call G[Fh] a fractional [a, b]-factor of G with indicator function h, where Fh = {e ...
Zhou Sizhong, Yang Fan, Sun Zhiren
doaj   +1 more source

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition

open access: yes, 2017
Introduction IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment.
Constantinou, N   +9 more
core   +2 more sources

Implementation of barycentric resampling for continuous wave searches in gravitational wave data [PDF]

open access: yes, 2010
We describe an efficient implementation of a coherent statistic for continuous gravitational wave searches from neutron stars. The algorithm works by transforming the data taken by a gravitational wave detector from a moving Earth bound frame to one that
B. F. Schutz   +5 more
core   +2 more sources

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