Results 31 to 40 of about 242,673 (264)

Edoxaban: an update on the new oral direct factor Xa inhibitor. [PDF]

, 2014
Edoxaban is a once-daily oral anticoagulant that rapidly and selectively inhibits factor Xa in a concentration-dependent manner. This review describes the extensive clinical development program of edoxaban, including phase III studies in patients with ...
A. John Camm, AC Skanes, AG Turpie, AJ Camm, AK Kakkar, AT Cohen, B Laulicht, BF Gage, BI Eriksson, BI Eriksson, BI Eriksson, BI Eriksson, BS Stambler, C Kearon, CB Granger, CT Ruff, DE Salazar, G Agnelli, G Agnelli, G Lu, G Raskob, G Raskob, H Masumoto, H Zahir, Henri Bounameaux, J Mendell, J Mendell, J Mendell, J Mendell, J Mendell, J Mendell, J Stampfuss, JH Alexander, JI Weitz, JL Mega, K Ogata, KL Furie, LT Grip, M Crowther, M Hori, M Pirmohamed, MR Lassen, MR Lassen, MR Lassen, MR Lassen, MR Patel, MS Bathala, MU Zafar, N Chung, N Matsushima, R Caterina De, R Caterina De, RP Giugliano, S Kaatz, S Schulman, S Schulman, S Schulman, SE Kimmel, SJ Connolly, SJ Connolly, SJ Connolly, SZ Goldhaber, T Fuji, T Fuji, T Fukuda, T Hulle van der, T Mikkaichi, T Wilke, T Yamashita, TI Verhoef, W Mueck, Y Falck-Ytter, Y Kuroda   +72 more
core   +1 more source

Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine-A Multicenter Trial [PDF]

, 2020
The rapid determination of the presence of direct oral anticoagulants (DOACs) in a patient remains a major challenge in emergency medicine and for rapid medical treatment decisions. All DOACs are excreted into urine.
Bauersachs, Rupert, Beyer-Westendorf, Jan, Crowther, Mark, Douxfils, Jonathan, Elalamy, Ismail, Harenberg, Job, Hetjens, Svetlana, Verhamme, Peter, Weiss, Christel   +8 more
core   +1 more source

The association of coagulation factor Xa and factor Va

Journal of Biological Chemistry, 1991
The binding of factor Xa to factor Va in the presence of Ca2+ ions and phospholipid is fundamental for the activation of prothrombin to thrombin. Nevertheless, the biochemistry of the intrinsic association between factors Xa and Va is poorly understood. In the present study we have measured the formation of the protein-protein complex in the absence of
Kenneth G. Mann, Edward L.G. Pryzdial
openaire   +3 more sources

Self‐Supporting Graphene Foam for the Removal of Chlorine from Water

Advanced Materials Interfaces, EarlyView.
Graphene‐based porous materials are promising for sorption and catalysis but often require binders. This study presents a self‐supporting graphene foam made from graphene oxide and hydrazine vapor. Structural, mechanical, and functional analyses confirm its superior chlorine removal efficiency (97%) and reusability, outperforming activated carbon in ...
Konrad Dybowski, Grzegorz Romaniak, Bartłomiej Januszewicz, Anna Sobczyk‐Guzenda, Jacek Grabarczyk, Adam K. Puszkarz, Anna Jędrzejczak   +6 more
wiley   +1 more source

A review of journal policies for sharing research data [PDF]

, 2008
*Background:* Sharing data is a tenet of science, yet commonplace in only a few subdisciplines. Recognizing that a data sharing culture is unlikely to be achieved without policy guidance, some funders and journals have begun to request and require that
Heather A. Piwowar, Wendy W. Chapman
core   +1 more source

Coagulation Factor Xa

, 2013
The third edition of the Handbook of Proteolytic Enzymes aims to be a comprehensive reference work for the enzymes that cleave proteins and peptides, and contains over 800 chapters. Each chapter is organized into sections describing the name and history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing
Brown, Mark A., Stenberg, Leisa M., Stenflo, Johan   +2 more
openaire   +1 more source

3D Printing of Highly Electrically Conductive Zinc for Sustainable Electronics Applications

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A 3D printable zinc ink system with active zinc particles in a shellac matrix is demonstrated. The results show high conductivity, stable performance of printed structures under varying humidity conditions, and promising application in disposable water‐activated batteries. This technology combining digital material assembly, reliable operation, and non‐
Xavier Aeby, Xiaomei Yan, Timon Huber, Aaron Schneider, Gilberto Siqueira, Gustav Nyström   +5 more
wiley   +1 more source

Quorum sensing genes rpfF and xanB2 are not essential for albicidin production nor sugarcane colonization by Xanthomonas albilineans [PDF]

, 2009
Xanthomonas albilineans (Xa) produces albicidin, a unique and specific toxin that causes foliar symptoms of sugarcane leaf scald disease. In X. campestris pv.
Fleites, Laura, Gabriel, Dean W., Marlow, Gary C., Rott, Philippe, Royer, Monique   +4 more
core  

The factor Xa-catalyzed activation of factor V.

Journal of Biological Chemistry, 1983
Factor V appears to be a procofactor with, at best, 1/400 the activity of fully activated Factor V (Factor Va). The proteolytic conversion of Factor V to Factor Va is catalyzed by thrombin. However, since Factor Va activity is required for thrombin generation, the initial participation of Factor V in the expression of prothrombinase activity is not ...
W B Foster, Kenneth G. Mann, Michael E. Nesheim   +2 more
openaire   +3 more sources

Dynamic Humidity Modulation of Quasi‐Bound States in the Continuum by Symmetry Breaking in Geometry and Permittivity

Advanced Photonics Research, EarlyView.
This work introduces a humidity‐modulated strategy to regulate the dynamic transition from quasi‐BICs to BICs based on the symmetry‐breaking in geometry and permittivity for the hybrid photonic‐plasmonic asymmetric gratings. It proves that it is a promising approach for dynamic regulating optical properties and applied in fabricating various micro ...
Ang Xu, Qiushun Zou, Hongsen Zhao, Yimin Chen, Chenjie Gu, Dandan Qiu, Xingyu Chen, Peiqing Zhang, Xiang Shen   +8 more
wiley   +1 more source