Results 71 to 80 of about 35,624 (244)

The new factor Xa inhibitor: Apixaban

Journal of Pharmacology and Pharmacotherapeutics, 2014
Cardiovascular diseases are still the most important cause of morbidity and mortality worldwide and anti-thrombotic treatment is widely used as a result. The currently used drugs include heparin and its derivatives, vitamin K antagonists, though efficacious, have their own set of limitations like unpredictable pharmacokinetic profile, parenteral route (
Bhanwra, Sangeeta, Ahluwalia, Kaza
openaire   +3 more sources

Starving for Data: Eating Disorders Prevalence and Research Gaps in Southern Africa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Studies reporting prevalence estimates of eating disorders in Southern Africa are scarce. To fill this gap, the present Research Forum reviews existing literature on the prevalence of eating disorders, including as assessed by clinical interviews, screeners, and self‐reported behaviors, among individuals in Southern Africa.
Bernou Melisse, Jojanneke M. Bijsterbosch, Lot Sternheim   +2 more
wiley   +1 more source

N‐Doped Carbon Encapsulated FeV2S4/Fe Nanorods as Fast‐Charging Anodes for All‐Climate Sodium‐Ion Storage

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The well‐chosen N‐doped carbon encapsulated FeV2S4/Fe nanorods as new anode materials exhibit remarkable all‐climate fast‐charging sodium storage properties. Various in‐situ/ex‐situ experimental characterizations and DFT calculations confirm the high electronic conductivity, fast Na+ diffusion and complex conversion‐based reaction mechanism.
Yanli Zhou, Qiming Li, Rui Liu, Ao Xu, Jiahui Wang, Xueqin Sun, Changlong Sun, Fuyi Jiang, Kai Xi, Jian Yang   +9 more
wiley   +1 more source

Semaglutide normalizes increased cardiomyocyte calcium transients in a rat model of high fat diet‐induced obesity

ESC Heart Failure, Volume 12, Issue 2, Page 1386-1397, April 2025.
Sequeira et al. reveal how the glucagon‐like peptide‐1 receptor agonist (GLP‐1‐RA) semaglutide restores cardiomyocyte function in rats subjected to a high‐fat/high‐fructose diet (HFD). Employing fluorescence‐ and patch‐clamp technology in isolated cardiac myocytes, they demonstrate that semaglutide reverses HFD‐induced activation of L‐type calcium ...
Vasco Sequeira, Julia Theisen, Katharina J. Ermer, Marie Oertel, Anton Xu, David Weissman, Katharina Ecker, Jan Dudek, Martin Fassnacht, Alexander Nickel, Michael Kohlhaas, Christoph Maack, Ulrich Dischinger   +12 more
wiley   +1 more source

Is the use of low molecular weight heparin a rational choice during pregnancy in patients with a mechanical heart valve: a report of three cases

Türk Kardiyoloji Derneği Arşivi, 2019
Pregnancy is associated with an increased risk of valve thrombosis in patients with a mechanical prosthetic heart valve. The administration of low molecular weight heparin (LMWH) with regular anti-factor Xa assessment is a recommended treatment modality ...
Ahmet Güner, Emrah Bayam, Semih Kalkan, Sabahattin Gündüz, Mehmet Özkan   +4 more
doaj   +1 more source

Analytical Floor Response Spectra for Performance‐Based Seismic Design of Non‐structural Elements in Reinforced Concrete Frame Buildings

Earthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Damage to non‐structural elements significantly impacts the seismic performance of buildings in terms of economic and functionality losses. Consequently, performance‐based seismic design of non‐structural elements has become a key pillar of a comprehensive building‐seismic resilience strategy, for instance, through loss‐targeted earthquake ...
Roberto J. Merino, Roberto Gentile, Carmine Galasso   +2 more
wiley   +1 more source

Real-world andexanet alfa utilization and the association between delay in administration due to hospital transfer and all-cause inpatient mortality

Research and Practice in Thrombosis and Haemostasis
Background: Evaluations of andexanet alfa for the reversal of factor Xa inhibitor-associated bleeding have been small, with cohorts drawn from single/limited sites.
Huiqiao Fan, Youssef Bessada, Craig I. Coleman   +2 more
doaj   +1 more source

High‐Resolution Ion Mobility Approach for Rapid Determination of Multiple Human Milk Oligosaccharide Isomer Ratios

Helvetica Chimica Acta, EarlyView.
ABSTRACT This study presents a high‐throughput ion mobility approach that integrates flow injection analysis (FIA) with multiple stitched high‐resolution ion mobility ranges to enable comprehensive analysis of human milk oligosaccharide (HMO) isomer mixtures in a single acquisition.
Wenqing Xu, Estelle Rathahao‐Paris, Blanche Guillon, François Fenaille, Karine Adel‐Patient, Sandra Alves   +5 more
wiley   +1 more source

The mediating role of the kynurenine pathway in longitudinal associations between dietary intake and quality of life in colorectal cancer survivors up to 12 months posttreatment

International Journal of Cancer, EarlyView.
What's New? Many colorectal cancer survivors experience reduced health‐related quality of life (HRQoL), often lasting years after diagnosis. Healthy dietary patterns and even individual macro‐ and micronutrients, however, can potentially improve HRQoL.
Daniëlle D. B. Holthuijsen, Judith J. M. Rijnhart, Eline H. van Roekel, Martijn J. L. Bours, Per M. Ueland, Stéphanie O. Breukink, Maryska L. G. Janssen‐Heijnen, Joop L. Konsten, Eric T. P. Keulen, Adrian McCann, Stefanie Brezina, Biljana Gigic, Jennifer Ose, Matty P. Weijenberg, Simone J. P. M. Eussen   +14 more
wiley   +1 more source

Alternative Price Dynamics and Valuation of Flexible Strategies

International Journal of Finance &Economics, EarlyView.
ABSTRACT In this article, we study the optimal operational strategy of production projects. We investigate different underlying price models and determine the optimal barriers of transition to suspension, recovery, or irreversible abandonment of productive activity.
Cristina Bertolosi, Gianluca Fusai, Ioannis Kyriakou   +2 more
wiley   +1 more source