Results 61 to 70 of about 13,359 (214)
Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels
Molecular Brain, 2023 The present study was undertaken to explore the relative contributions of Cav3.2 T-type channels to mediating the antihyperalgesic activity of joint manipulation (JM) therapy.
Daniel F. Martins +6 more
doaj +1 more source
Plant, Cell &Environment, EarlyView.ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo +5 more
wiley +1 more source
, 2017 Fatty acid amide hydrolase (FAAH) is one of the key enzymes involved in the biological degradation of endocannabinoids, especially anandamide.
Yuhang Li +7 more
core +1 more source
Cellular Physiology and Biochemistry, 2018 Background/Aims: Recent interest in the use of cannabinoids as therapeutic agents has revealed the involvement of the endogenous cannabinoid system (ECS) in the regulation of the cardiovascular system in hypertension.
Agnieszka Polak +5 more
doaj +1 more source
Frontiers in Pharmacology, 2020 In a prospective, randomized, three-arms, controlled clinical study, Chinese Herbal Medicine MaZiRenWan (MZRW, also known as Hemp Seed Pill) demonstrates comparable efficacy with Senna for functional constipation (FC) during an 8-week treatment period ...
Tao Huang +11 more
doaj +1 more source
Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
The Journal of Physiology, EarlyView.Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Frontiers in Pharmacology, 2016 This perspective was adapted from a Career Achievement Award talk given at the International Cannabinoid Research Society Symposium in Bukovina, Poland on June 27, 2016.
Dale Deutsch
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos +7 more
wiley +1 more source
Expression and function of fatty acid amide hydrolase in prostate cancer [PDF]
International Journal of Cancer, 2008 AbstractThe hydrolysis of endocannabinoids has profound effects on the function of the endocannabinoid signaling system in the regulation of prostate carcinoma cells. Prostate carcinoma cells exhibit a wide range of hydrolysis activity for 2‐arachidonoylglycerol (2‐AG), the major endocannabinoid.
Michael P, Endsley +6 more
openaire +2 more sources
European Journal of Pain, Volume 30, Issue 6, July 2026.ABSTRACT Background Fibromyalgia is a syndrome characterised by widespread chronic pain, which is believed to be mediated by a state of central sensitisation (CS). Based on the hypothesis that CS itself could have genetic determinants, our aim was to further explore this pathway.
Nicolas Macian +8 more
wiley +1 more source