Serum Nonesterified Fatty Acids and Incident Stroke: The CHS [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background Significant associations between total nonesterified fatty acid (NEFA) concentrations and incident stroke have been reported in some prospective cohort studies.
Neil K. Huang +7 more
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The effects of saturated fatty acid supplements on plasma and milk concentration of fatty acid esters of hydroxy fatty acids in dairy cows [PDF]
JDS CommunicationsFatty acid esters of hydroxy fatty acids (FAHFA) are a novel class of bioactive lipids with demonstrated antidiabetic and anti-inflammatory properties in rodent models and humans but have not been investigated in cows.
M. Arif +5 more
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Association between plasma nonesterified fatty acids species and adipose tissue fatty acid composition. [PDF]
PLoS ONE, 2013 Fatty acid composition of adipose tissue (AT) is an established long-term biomarker for fatty acid (FA) intake and status, but AT samples are not easily available.
Christian Hellmuth +5 more
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Quantitative extraction and determination of nonesterified fatty acids in plasma
Journal of Lipid Research, 1973 A method is described for the determination of nonesterified fatty acids in plasma. Extraction is at least 98% efficient, and losses during subsequent stages are corrected for by the use of an internal radioactive standard.
W.G. Duncombe, T.J. Rising
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Effects of timing of abomasal infusion of fatty acids on the daily rhythms of milk synthesis and plasma hormones and metabolites in dairy cows [PDF]
Journal of Dairy Science: Dairy cows display daily rhythms of milk synthesis that appear to be driven by a circadian clock located in the mammary gland. These rhythms are altered by the time of feed availability. Fatty acids have been shown to entrain circadian rhythms in liver
I.J. Salfer +2 more
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Scientific Reports, 2021 Colorectal cancer (CRC) is a major cancer, and its precise diagnosis is especially important for the development of effective therapeutics. In a series of metabolome analyses, the levels of very long chain fatty acids (VLCFA) were shown to be elevated in
Kotaro Hama +7 more
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Substrate modulation of fatty acid effects on energization and respiration of kidney proximal tubules during hypoxia/reoxygenation. [PDF]
PLoS ONE, 2014 Kidney proximal tubules subjected to hypoxia/reoxygenation develop a nonesterified fatty acid-induced energetic deficit characterized by persistent partial mitochondrial deenergization that can be prevented and reversed by citric acid cycle substrates ...
Anja Bienholz +5 more
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Regulation of Insulin Clearance by Non-Esterified Fatty Acids
Biomedicines, 2022 Insulin stores lipid in adipocytes and prevents lipolysis and the release of non-esterified fatty acids (NEFA). Excessive release of NEFA during sustained energy supply and increase in abdominal adiposity trigger systemic insulin resistance, including in
Sonia M. Najjar +8 more
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Nonesterified Fatty Acids, Albumin, and Platelet Aggregation [PDF]
Diabetes, 2015 It has been known for five decades that nonesterified fatty acids (NEFAs) have a role in the activation of platelets and thrombosis. Thus, the infusion of NEFAs leads to massive thrombosis and platelet activation (1–4). It has also been shown that their binding to albumin protects the platelets from activation (5).
Sandeep, Dhindsa +2 more
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Perceptual Quality of Nonesterified Fatty Acids Varies with Fatty Acid Chain Length
Chemical Senses, 2021 Abstract Nonesterified fatty acids (NEFA) are effective taste stimuli. The quality they impart has not been well characterized. Sourness, and “fattiness” have been reported, but an irritation component has also been described and how these transition with gradations of aliphatic chain length has not been systematically studied.
Eunjin Cheon, Richard D Mattes
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