Results 11 to 20 of about 13,988 (224)

Acyl-CoA Binding Protein in White and Brown Adipose Tissue Is Dispensable for Systemic Energy Metabolism in Mice. [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim Acyl‐CoA binding protein plays a vital role in lipid metabolism by mediating the intracellular flux and utilization of long‐chain acyl‐CoAs. We generated an adipocyte‐wide ACBP knockout mouse and a brown adipose tissue‐specific ACBP knockout mouse to investigate ACBP function in adipose tissue.
Nørremark MF, Petersen R, Ruppert PMM, Jul ES, Doktor TK, Nielsen R, Kappel JF, Larsen S, Kornfeld JW, Mandrup S, Andresen BS, Havelund J, Neess D, Færgeman NJ.   +13 more
europepmc   +2 more sources

Proximal Tubule-Specific Genetic Deficiency of PPARα Worsens Systemic Lipid and Glucose Metabolism During Fasting. [PDF]

FASEB J
Proximal tubule‐specific PPARα knockout mouse (PPARαΔKPT) showed decreased lipid and glucose metabolism in the kidney during fasting. Metabolism in the other organs was increased, presumably as a means of compensating for the impaired kidney metabolism.
Aomura D, Nimura T, Yamaka K, Yamada Y, Harada M, Nakajima T, Kimura T, Hashimoto K, Kanno H, Yanagita M, Gonzalez FJ, Tanaka N, Kamijo Y.   +12 more
europepmc   +2 more sources

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan, Yuhong Luo, Nana Yan, Keisuke Hamada, Nan Zhao, Yangliu Xia, Ping Wang, Changdong Zhao, Dan Qi, Shoumei Yang, Lulu Sun, Jie Cai, Qiong Wang, Changtao Jiang, Oksana Gavrilova, Kristopher W. Krausz, Daxesh P. Patel, Xiaoting Yu, Xuan Wu, Haiping Hao, Weiwei Liu, Aijuan Qu, Frank J. Gonzalez   +22 more
wiley   +1 more source

Bile Acid Binding Resins Improve Glucagon Receptor Agonist-Mediated Weight Loss in Diet-Induced Obese Mice. [PDF]

Obesity (Silver Spring)
ABSTRACT Objective Glucagon‐receptor (GCGR) agonism reguglates bile acid (BA) metabolism and promotes weight loss in diet‐induced obese (DIO) mice. Thus, we hypothesized that BA signaling contributes to GCGR‐stimulated weight loss. Methods To test this hypothesis, we utilized BA‐binding resins (BARs; colesevelam [Colsv] and cholestyramine [Cstyr]) to ...
Kim T, Pearson MJ, Hong H, Nason S, Seck K, Antipenko J, Presedo N, DiMarchi R, Roell WC, Habegger K.   +9 more
europepmc   +2 more sources

Effects of Lysolecithin on Growth Performance, Nutrient Digestibility, Serum Biochemical Indices, and Rumen Environment in Holstein Calves. [PDF]

Food Sci Nutr
Lysolecithin increased serum albumin, total antioxidant capacity, and total cholesterol, while decreased non‐esterified fatty acid, blood urea nitrogen and triglyceride. Lysolecithin increased percentage of butyrate, iso‐butyrate, valerate and iso‐valerate in rumen fluid. The abundance of Ruminococcus in the addition of lysolecithin was higher compared
An Z, Pan S, He B, Wang J, Wang Y, Sun S, Wang C.   +6 more
europepmc   +2 more sources

Demonstration of two pools of albumin-bound fatty acids

Journal of Lipid Research, 1975
The uptakes of albumin-bound nonesterified fatty acids and of [1-14C]palmitic acid complexed to albumin by the isolated perfused rat liver were compared. During perfusion, the rate of uptake of nonesterified fatty acids decreased and became zero when the
C. Soler-Argilaga, R. Infante, J. Polonovski   +2 more
doaj   +1 more source

In vitro effects of nonesterified fatty acids on bovine neutrophils oxidative burst and viability [PDF]

, 2006
An in vitro study was conducted to examine the influence of nonesterified fatty acids (NEFA) on bovine polymorphonuclear leukocytes (PMN). Eight healthy, midlactating Holstein cows were used as blood donors.
BERNABUCCI, U, Burvenich, Christian, Demeyere, Kristel, Duchateau, Luc, LACETERA, N, SCALIA, D   +5 more
core   +1 more source

Reformulation initiative for partial replacement of saturated with unsaturated fats in dairy foods attenuates the increase in LDL cholesterol and improves flow-mediated dilatation compared with conventional dairy: the randomized, controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) study [PDF]

, 2020
Background Modifying dairy fat composition by increasing the MUFA content is a potential strategy to reduce dietary SFA intake for cardiovascular disease (CVD) prevention in the population.
Fagan, Colette C., Givens, David I., Grandison, Alistair S., Humphries, David J., Jackson, Kim G., Kliem, Kirsty E., Lovegrove, Julie A., Markey, Oonagh, Todd, Sue, Vasilopoulou, Dafni   +9 more
core   +2 more sources

Cationic Polystyrene Resolves Nonalcoholic Steatohepatitis, Obesity, and Metabolic Disorders by Promoting Eubiosis of Gut Microbiota and Decreasing Endotoxemia. [PDF]

, 2017
A pandemic of metabolic diseases, consisting of type 2 diabetes, nonalcoholic fatty liver disease, and obesity, has imposed critical challenges for societies worldwide, prompting investigation of underlying mechanisms and exploration of low-cost and ...
Bai, Li, Chen, Jingjing, Chen, Zishou, Duan, Yixiang, Duan, Zhongping, Han, Yuan-Ping, Hu, Richard, Ju, Zhongyuan, Li, Wenwen, Li, Yan, Liu, Yong, Luo, Mei, Pandol, Stephen J, Su, Danmei, Sun, Qun, Wu, Pengfei, Xiao, Zhixiong, Zeng, Yilan, Zhang, Li, Zhang, Xiaohui, Zheng, Han, Zheng, Sujun, Zhu, Airu   +22 more
core   +1 more source

Long chain nonesterified fatty acid patterns in plasma of healthy children and young adults in relation to age and sex.

Journal of Lipid Research, 1981
In a large group of healthy Belgian children and young adults, the absolute and relative concentrations of nonesterified fatty acid patterns were determined by an appropriate gas-liquid chromatographic technique.
V Rogiers
doaj   +1 more source