Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]
Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin+10 more
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Effect of diet-induced obesity on protein expression in insulin signalling pathways of skeletal muscle in male Wistar rats [PDF]
BACKGROUND: The prevalence of diet-induced obesity is increasing globally, and posing significant health problems for millions of people worldwide. Diet-induced obesity is a major contributor to the global pandemic of type 2 diabetes mellitus.
Abubakari, Abdul-Razak+5 more
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Influences of Repeated Testing on Nonesterified Fatty Acid Taste [PDF]
Findings that support the ability of humans to taste nonesterified fatty acids have been qualified by claims of substantial individual variability in sensitivity. We tested whether the number of testing visits impacted detection thresholds. Additionally, we explored the possibility that methodological differences in reported studies contributed to the ...
Robin M. Tucker, Richard D. Mattes
openaire +2 more sources
Essential fatty acids and their long-chain polyunsaturated metabolites in maternal and cord plasma triglycerides during late gestation [PDF]
The fatty acid composition of plasma lipids was determined in 41 pairs of mothers and their term infants at time of birth (38-42 postmenstrual weeks) by high-resolution capillary gas-liquid chromatography, Linoleic and alpha-linolenic acids were found at
Berghaus, Thomas M.+2 more
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Short-term therapy with rosiglitatzone, a PPAR-¿ agonist improves metabolic profile and vascular function in non-obese lean wistar rats [PDF]
A number of preclinical and clinical studies have reported blood-pressure-lowering benefits of thiazolidinediones in diabetic subjects and animal models of diabetes.
Abubakari, Abdul-Razak+3 more
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Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A.+9 more
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Evaluation of the diagnostic accuracy of a point-of-care device to measure concentrations of nonesterified fatty acids in serum and whole blood [PDF]
The objective of this study was to compare measurements of nonesterified fatty acids (NEFA) between the gold standard diagnostic laboratory method and a handheld NEFA meter (Qucare Pro meter, DFI Co. Ltd.).
Borchardt, Stefan+4 more
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A comparison of total-mixed-ration and feed-to-yield strategies on blood profiles and dairy cow health. [PDF]
Seventy-two Holstein-Friesian dairy cows were offered the same amount of concentrates over the first 140 days of lactation, by either a ‘total-mixed-ration’ or a ‘feed-to-yield’ strategy. The effects on blood profiles and cow health were examined.
Arnott, Gareth+5 more
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Nonesterified Fatty Acids and Hepatic Glucose Metabolism in the Conscious Dog [PDF]
We used tracer and arteriovenous difference techniques in conscious dogs to determine the effect of nonesterified fatty acids (NEFAs) on net hepatic glucose uptake (NHGU). The protocol included equilibration ([3-3H]glucose), basal, and two experimental periods (−120 to −30, −30 to 0, 0–120 [period 1], and 120–240 min [period 2], respectively).
Margaret Lautz+6 more
openaire +3 more sources
Sustained nonoxidative glucose utilization and depletion of glycogen in reperfused canine myocardium [PDF]
Ischemically injured reperfused myocardium is characterized by increased 18F-fluorodeoxyglucose uptake as demonstrated by positron emission tomography. To elucidate the metabolic fate of exogenous glucose entering reperfused myocardium, D-[6-14C] glucose
Araujo, Louis+13 more
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