Effect of diet-induced obesity on protein expression in insulin signalling pathways of skeletal muscle in male Wistar rats [PDF]
, 2012 BACKGROUND: The prevalence of diet-induced obesity is increasing globally, and posing significant health problems for millions of people worldwide. Diet-induced obesity is a major contributor to the global pandemic of type 2 diabetes mellitus.
Abubakari, Abdul-Razak +5 more
core +2 more sources
The Role of TCA Cycle Anaplerosis in Ketosis and Fatty Liver in Periparturient Dairy Cows
Animals, 2015 The transition to lactation period in dairy cattle is characterized by metabolic challenges, negative energy balance, and adipose tissue mobilization. Metabolism of mobilized adipose tissue is part of the adaptive response to negative energy balance in ...
Heather M. White
doaj +1 more source
Short-term therapy with rosiglitatzone, a PPAR-¿ agonist improves metabolic profile and vascular function in non-obese lean wistar rats [PDF]
, 2012 A number of preclinical and clinical studies have reported blood-pressure-lowering benefits of thiazolidinediones in diabetic subjects and animal models of diabetes.
Abubakari, Abdul-Razak +3 more
core +1 more source
Influences of Repeated Testing on Nonesterified Fatty Acid Taste [PDF]
Chemical Senses, 2013 Findings that support the ability of humans to taste nonesterified fatty acids have been qualified by claims of substantial individual variability in sensitivity. We tested whether the number of testing visits impacted detection thresholds. Additionally, we explored the possibility that methodological differences in reported studies contributed to the ...
Robin M, Tucker, Richard D, Mattes
openaire +2 more sources
Metabolic, inflammatory, and oxidative stress markers in women exposed to secondhand smoke [PDF]
PeerJ, 2018 Background Secondhand smoke (SHS) exposure has adverse effects on the cardiovascular system. This study aimed to determine the effects of SHS on the cardiovascular disease biomarkers, namely the metabolic, inflammatory, and oxidative stress markers in ...
Mohd Hanaffi Siti Hajar +6 more
doaj +2 more sources
Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]
, 2013 Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A. +9 more
core +2 more sources
Renal norepinephrine spillover during infusion of nonesterified fatty acids [PDF]
American Journal of Hypertension, 2005 Sympathetic activity and renal norepinephrine spillover are increased in obese individuals. We have reported that infusion of nonesterified fatty acids increases blood pressure in animals through stimulation of the sympathetic nervous system.In this study, we assessed the effect of increasing circulating nonesterified fatty acids on systemic and renal ...
Roger J, Grekin +3 more
openaire +2 more sources
In vivo investigation of the placental transfer of 13C-labeled fatty acids in humans
Journal of Lipid Research, 2003 Placental fatty acid transfer in humans in vivo was studied using stable isotopes. Four pregnant women undergoing cesarean section received 4 h before delivery an oral dose of [13C]palmitic acid (37), [13C]oleic acid (OA), [13C]linoleic acid (LA), and ...
Elvira Larqué +4 more
doaj +1 more source
Integration Analysis of Metabolome and Transcriptome Reveals the Effect of Lipopolysaccharide on Ovary Response to Stimulation. [PDF]
Immun Inflamm DisThis study provided evidence of inflammation on damaging ovary response to controlled ovarian stimulation, linked to dysfunctions in lipid, carbohydrate, and amino acid metabolism. IL‐17 signal pathways may play a critical role in this process. ABSTRACT Objective This study aimed to elucidate the underlying mechanisms by which lipopolysaccharide (LPS ...
Mu X, Zhu F, Zhang Y, Pei ML.
europepmc +2 more sources
A Review of the Metabolic Origins of Milk Fatty Acids
Notulae Scientia Biologicae, 2013 Milk fat and its fatty acid profile are important determinants of the technological, sensorial, and nutritional properties of milk and dairy products. The two major processes contributing to the presence of fatty acids in ruminant milk are the mammary ...
Anamaria COZMA +5 more
doaj +3 more sources