Results 71 to 80 of about 13,450 (208)

Maximal Oxidative Capacity during Exercise Is Associated with Skeletal Muscle Fuel Selection and Dynamic Changes in Mitochondrial Protein Acetylation [PDF]

, 1995
SummaryMaximal exercise-associated oxidative capacity is strongly correlated with health and longevity in humans. Rats selectively bred for high running capacity (HCR) have improved metabolic health and are longer-lived than their low-capacity ...
Overmyer, Katherine A., Evans, Charles R., Qi, Nathan R., Minogue, Catherine E., Carson, Joshua J., Chermside-Scabbo, Christopher J., Koch, Lauren G., Britton, Steven L., Pagliarini, David J., Coon, Joshua J., Burant, Charles F.   +10 more
core   +1 more source

Food insecurity promotes adiposity in mice

Obesity, Volume 33, Issue 6, Page 1087-1100, June 2025.
Abstract Objective The obesity epidemic, driven by a complex interplay of environmental and biological factors, remains a significant global health challenge. Herein, we investigate the impact of food insecurity, characterized by unpredictable food access, on the regulation of body weight and body composition in mice.
Cláudia R. E. Gil, Jens Lund, Jan J. Żylicz, Pablo Ranea‐Robles, Thorkild I. A. Sørensen, Christoffer Clemmensen   +5 more
wiley   +1 more source

A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans [PDF]

, 2006
BACKGROUND: High fructose consumption is suspected to be causally linked to the epidemics of obesity and metabolic disorders. In rodents, fructose leads to insulin resistance and ectopic lipid deposition.
Austin, Bantle, Boesch, Boesch, Bray, Cammisotto, Carmona, Chicco, Chris Boesch, David Faeh, DeFronzo, DeFronzo, Durnin, D’Alessio, Elliott, Eric Ravussin, Faeh, Felblinger, Finegood, Furuhashi, Hallfrisch, Havel, Henry, Hollander, Hollenbeck, Jallut, Jurgens, Kim-Anne Lê, Lee, Livesey, Luc Tappy, Michael Ith, Moore, Nagai, Pagliassotti, Pagliassotti, Park, Parks, Peter Vermathen, Rodrigue Stettler, Roland Kreis, Schneiter, Tappy, Teff, Thresher   +44 more
core   +1 more source

The influence of placental metabolism on fatty acid transfer to the fetus

Journal of Lipid Research, 2017
The factors determining fatty acid transfer across the placenta are not fully understood. This study used a combined experimental and computational modeling approach to explore placental transfer of nonesterified fatty acids and identify the rate ...
Simone Perazzolo, Birgit Hirschmugl, Christian Wadsack, Gernot Desoye, Rohan M. Lewis, Bram G. Sengers   +5 more
doaj  

Peripheral, but not central, CB1 antagonism provides food intake-independent metabolic benefits in diet-induced obese rats. [PDF]

, 2008
OBJECTIVE Blockade of the CB1 receptor is one of the promising strategies for the treatment of obesity. Although antagonists suppress food intake and reduce body weight, the role of central versus peripheral CB1 activation on weight loss and related ...
Caldwell, Charles, Fekete, Csaba, Klein, Marcella, Liposits, Zsolt, Nogueiras, Ruben, Reizes, Ofer, Rohner-Jeanrenaud, Francoise, Suchanek, Paula M., Tschöp, Johannes, Tschöp, Matthias H., Veyrat-Durebex, Christelle, Watanabe, Masahiko, Wittmann, Gábor, Woods, Stephen C.   +13 more
core   +2 more sources

Antiresistin RNA oligonucleotide ameliorates diet-induced nonalcoholic fatty liver disease in mice through attenuating proinflammatory cytokines [PDF]

, 2015
© 2015 Yi Tan et al. The aim of this study was to determine whether inhibition of resistin by a synthetic antiresistin RNA (oligonucleotide) oligo ameliorates metabolic and histological abnormalities in nonalcoholic fatty liver disease (NAFLD) induced by
Jin, XL, Kim, J, Lao, W, Qu, X, Tan, Y, Xiao, L   +5 more
core   +4 more sources

Role of adipokines and nonesterified fatty acids in the development of insulin resistance

Problems of Endocrinology, 2009
The purpose of the study was to reveal a possible role of adipokines, biologically active adipose tissue proteins (leptin and adiponectin) and nonesterified fatty acids in generating insulin resistance (IR). One hundred and fifty-seven patients (90 females and 67 males) aged 57.5±9.2 years were enrolled in the study. According to the HOMA index for IR,
E M Firova, Dmitry A. Tanyanskiy, A. D. Denisenko, L V Shatilina   +3 more
openaire   +3 more sources

Effect of Insulin on Human Plasma Tryptophan and Nonesterified Fatty Acids

Experimental Biology and Medicine, 1977
SummaryOne hour after insulin administration to healthy, fasting humans, plasma nonesterified fatty acid (NEFA) levels decreased by approximately 40% of the prein-jection value. Contrary to predictions, plasma free tryptophan did not change and plasma bound tryptophan decreased by 12% during the 1 hr after insulin administration.
Joseph Rochford, M. Swartzburg, Paul Manowitz, M. Menna-Perper, Mueller Ps   +4 more
openaire   +3 more sources

A study on the causes for the elevated n−3 fatty acids in cows' milk of alpine origin [PDF]

, 2018
The influence of grass-only diets either from rye-grass-dominated lowland pastures (400 m above sea level) or botanically diverse alpine pastures (2000 m) on the FA profile of milk was investigated using three groups of six Brown Swiss cows each.
Kreuzer, Michael, Leiber, Florian, Leo Scheeder, Martin, Nigg, Daniel, Wettstein, Hans-Rudolf   +4 more
core  

Functionality of fatty acid chemoreception : a potential factor in the development of obesity? [PDF]

, 2013
Excess dietary fat consumption is recognized as a strong contributing factor in the development of overweight and obesity. Understanding why some individuals are better than others at regulating fat intake will become increasingly important and emerging ...
Cordain, Feltrin, Gibson, Gilbertson, Heini, Kawai, Lisa Newman, Little, Matsumura, Mattes, Mattes, Newman, Pepino, Rivkeh Haryono, Rolls, Russell Keast, Simons, Snoek, Stewart, Turnbull   +19 more
core   +2 more sources