Results 251 to 260 of about 304,657 (328)

Tissue‐Specific Regulation of Fatty Acid Metabolism in a Mouse Model of Isolated Complex I Deficiency

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Isolated complex I deficiency (ICD) is commonly associated with mitochondrial diseases and closely mimics subacute necrotising encephalomyelopathy. This disorder is characterised by metabolic perturbations that affect energy metabolism pathways, including fatty acid metabolism.
Sibonelo Glen Khumalo   +2 more
wiley   +1 more source

Functional Foods, a Hope to Delay Muscle Dystrophy Progression: A Potential Role for Omega Fatty Acids. [PDF]

open access: yesNutrients
Versari I   +7 more
europepmc   +1 more source

Model‐Based Meta‐Analysis of the Relationship Between Pioglitazone and Histological Outcomes in Metabolic Dysfunction‐Associated Steatohepatitis Patients

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Given the high prevalence of the population who have metabolic dysfunction‐associated steatohepatitis (MASH), interest is growing in MASH‐targeted treatments. However, currently, there has been only one regulatory approved drug for MASH (Rezdiffra).
Quyen Thi Tran   +11 more
wiley   +1 more source

Influence of Cosolvents on the Pressure Stability of Human Serum Albumin

open access: yesphysica status solidi (a), EarlyView.
Human serum albumin is able to bind various hydrophobic substances and drugs. To investigate this interaction, the protein structure is analyzed using small‐angle X‐ray scattering under high hydrostatic pressure. The resulting radius of gyration (see picture) indicates that hydrophobic substances influence the pressure stability of HSA differently ...
Jaqueline Savelkouls   +3 more
wiley   +1 more source

Near‐Infrared Emission Perovskites for Multifunctional Bioimaging

open access: yesSmall Science, EarlyView.
Currently, the acquisition of information inside living organisms is highly dependent on a variety of photodetectors with different response ranges, for which a near‐infrared‐emitting perovskite material has been designed that exhibits excellent performance under both UV and X‐ray irradiation, enabling multimodal imaging of biological tissues with only
Tianchi Wang   +9 more
wiley   +1 more source

Gut Microbiota as a Mediator Between Intestinal Fibrosis and Creeping Fat in Crohn's Disease

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Intestinal stricture remains one of the most challenging complications in Crohn's disease, and its underlying mechanisms are poorly understood. Accumulating evidence suggests that gut microbiota is significantly altered in stenotic intestines and may play a key role in the development of fibrogenesis in Crohn's disease.
Caiguang Liu   +14 more
wiley   +1 more source

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