Identification of FDFT1 as a potential biomarker associated with ferroptosis in ccRCC
Cancer Medicine, 2022 Renal cell carcinoma (RCC) seriously threatens people's lives and health. The identification of some precise biomarkers during the process of RCC progression and the pathophysiologic procedure is critical for improving the diagnosis and management of RCC.
Ruizhen Huang +8 more
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Cancer Treatment and Research Communications, 2022 According to previous reports,10–16% of patients with clinically advanced cholangiocarcinoma develop FGFR2 fusions or rearrangements. Treatment with FGFR2-specific inhibitors (tyrosine kinase inhibitors, TKIs) has proven effective for patients with ...
Chunye Huang +6 more
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Raman spectroscopy biochemical characterisation of bladder cancer cisplatin resistance regulated by FDFT1: a review [PDF]
Cellular & Molecular Biology Letters, 2022 Bladder cancer is the fourth most common malignancy in males. It can present across the whole continuum of severity, from mild through well-differentiated disease to extremely malignant tumours with poor survival rates.
M. Kanmalar +7 more
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Retraction Note: Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression [PDF]
Nature CommunicationsMei-lin Weng +15 more
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RETRACTED ARTICLE: Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression [PDF]
Nature Communications, 2020 Evidence suggests that fasting exerts extensive antitumor effects in various cancers, including colorectal cancer (CRC). However, the mechanism behind this response is unclear.
Mei-lin Weng +15 more
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FDFT1 inhibits macrophage M1 polarization and promotes colorectal cancer progression
陆军军医大学学报Objective To screen the targets related to the metabolic enzymes involved in the cholesterol synthesis pathway that inhibits the polarization of macrophages towards M1 phenotype, and verify the intervention effects and underlying mechanisms in ...
GAO Yuan, HUANG Yulan, ZHAO Kun
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Studies of
BMC Medical Genetics, 2009 Background A genome-wide scan in unrelated US Caucasians identified rs7001819 upstream of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) and multiple variants within catenin (cadherin-associated protein), β-like 1 (CTNNBL1) to associate strongly with
Almind Katrine +9 more
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3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility [PDF]
Genome BiologyBackground Insight into the genetic basis for many common autoimmune disorders has been uncovered by genome-wide association studies (GWAS), but this alone does not reveal causal variants, effector genes, or the cell types impacted by disease-associated ...
Khanh B. Trang +29 more
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Dual Regulatory Mechanisms of Expression and Mutation Involving Metabolism-Related Genes FDFT1 and UQCR5 during CLM [PDF]
Molecular Therapy: Oncolytics, 2019 Colorectal cancer (CRC) is the third most common cancer worldwide, and liver metastasis presents a major cause of CRC-associated death. Extensive genomic analysis has provided valuable insight into the pathogenesis and progression of CRC; however, a ...
Yu-Shui Ma +16 more
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Integrative analysis of metabolomics and transcriptomics reveals alterations in egg quality and hepatic lipid metabolism in hens supplemented with curcumin [PDF]
Animal NutritionCurcumin has been shown to affect lipid metabolism in various ways, but its molecular mechanisms in hens remain poorly understood. In this study, 378 Hy-Line Brown hens, aged 58 weeks, were randomly assigned into three groups, each consisting of 6 ...
Cunzhi Zou +4 more
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