Results 101 to 110 of about 4,897,809 (228)

Status and Prospect of Radiolabeled Small Molecule Inhibitors as Tumor Imaging Agents Targeting FAP

Journal of Isotopes
: Fibroblast activation protein (FAP) exists in tumor stromal fibroblasts and is a significant target for tumor diagnosis and treatment recently. Among the radioactive FAP-targeted tumor imaging agents, small-molecule tracers have received the most ...
HAN Peiwen1, RUAN Qing1, 2, ZHANG Junbo1
doaj   +1 more source

Clinicopathological characteristics of HCCs according to CCN2, EMA, and FAP expression in cohort 1 (n = 314).

, 2014
HCC, Hepatocellular carcinoma; CCN2, Connective tissue growth factor; EMA, Epithelial membrane antigen; FAP, Fibroblast activation protein.
Gi Jeong Kim (462577), Hyungjin Rhee (616104), Jeong Eun Yoo (616105), Jin Sub Choi (616108), Jung Eun Ko (616106), Jee San Lee (616107), Young Nyun Park (149284), Hyunki Kim (462578)   +7 more
core   +1 more source

Molecular networks in FGF signaling: Flotillin-1 and Cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2 [PDF]

, 2012
Fibroblast growth factor receptor substrate 2 (FRS2α) is a signaling adaptor protein that regulates downstream signaling of many receptor tyrosine kinases.
Traub Stephanie, Tomasovic, Ana, Stephanie Traub, Ana Tomasovic, Ana Tomasovic (189773), Ritva Tikkanen (189783), Tikkanen Ritva, Tikkanen, Ritva, Traub, Stephanie, Tomasovic Ana, Ritva Tikkanen, Stephanie Traub (189777)   +11 more
core   +2 more sources

Digital analysis of spatial expression of stromal fibroblast activation protein alpha (FAP) in DCIS

Histopathology, EarlyView.
Digital analysis of FAP expression in DCIS revealed a higher FAP level around DCIS with nearby invasion, comparable to invasive carcinoma. High FAP correlated with nuclear grade, papillary DCIS and HER2 subtype, showing prognostic potential. Introduction The presence of non‐progressing ductal carcinoma in situ (DCIS) cases has raised concerns of ...
Ka Long Leung, Ronald C Chan, Conrad H Lee, Ngou‐Men Wong, Monalyn Marabi, Shirley K Jamidi, Yun‐Bi Ni, Julia Y Tsang, Man‐Chi Eric Fu, Dajiang Guo, Gary M Tse   +10 more
wiley   +1 more source

A novel fibroblast activation protein-targeted near-infrared fluorescent off-on probe for cancer cell detection, &ITin vitro&IT and &ITin vivo &ITimaging

, 2018
A new hemicyanine-based fibroblast activation protein-targeted near-infrared fluorescent probe is designed and it shows high selectivity and sensitivity to cancer cell detection, and in vitro and in vivo imaging.
Xiang, Lingchao, Li, Zihou, Xing, Jie, Xia, Yuanzhi, Wu, Aiguo, Yu, Zhangsen, Ye, Yufan, Zou, Ruifen, Gong, Qiuyu   +8 more
core  

Overall and disease free survival curves using the Kaplan–Meier method by log-rank test for cancer associated fibroblast (CAF)-activation protein expression: (A, F) SMA; (B, G) FSP1; (C, H) FAP; (D, I) PDGFRα; (E, J) PDGFRβ.

, 2014
Overall and disease free survival curves using the Kaplan–Meier method by log-rank test for cancer associated fibroblast (CAF)-activation protein expression: (A, F) SMA; (B, G) FSP1; (C, H) FAP; (D, I) PDGFRα; (E, J) PDGFRβ.
Sang Yun Ha (580178), Yan-hiua Xuan (580180), So-Young Yeo (580179), Seok-Hyung Kim (280362)   +3 more
core   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

IL-17a promotes hepatocellular carcinoma by increasing FAP expression in hepatic stellate cells via activation of the STAT3 signaling pathway

Cell Death Discovery
Studies have shown that hepatic stellate cells (HSCs) and interleukin-17a (IL-17a) play important roles in liver tumorigenesis. In addition, fibroblast activation protein-α (FAP) has been shown to be a key regulator of hepatic stellate cell activation ...
Dapeng Sun, Wen Li, Dongyang Ding, Kunjiang Tan, Wenbin Ding, Zongyan Wang, Siyuan Fu, Guojun Hou, Wei-ping Zhou, Fangming Gu   +9 more
doaj   +1 more source

Ekspresi Imunohistokimia Fibroblast Activation Protein (FAP) pada Subtipe Karsinoma Endometrium di Departemen Patologi Anatomik Fakultas Kedokteran Universitas Sumatera Utara / RSUP H. Adam Malik Medan

, 2021
Background: Fibroblast activation protein (FAP) is a cell surface antigen that is expressed on reactive stromal fibroblasts of cancer epithelial cells and appears as an important factor in cancer-associated fibroblasts (CAF), which is relevant in ...
Fiandani, Fatma Zulita
core