Results 121 to 130 of about 4,897,809 (228)
Secondary lymphedema was induced in New Zealand White rabbits by popliteal lymph node excision and afferent lymphatic vessel ligation, causing sustained hind limb swelling. LVA was performed immediately or after 4, 8, or 12 weeks. Patency was verified intraoperatively by microsuturing and postoperatively by indocyanine green (ICG) lymphangiography ...
Ping Zhao +5 more
wiley +1 more source
Objective: to determine the degree of expression of Fibroblast Activation Protein in Cancer Associated Fibroblasts of colorectal carcinoma. Methods: descriptive study with a cross sectional research design.
Vonny Amalia
doaj +1 more source
Fibro‐Adipogenic Progenitors From Skeletal Muscle Enhance Microvascular Angiogenesis in a 3D Model
Fibro‐adipogenic progenitors (FAPs) are skeletal muscle stem cells that reside between fibers and near capillaries. However, relatively few studies have investigated interactions between FAPs and the microvasculature. We demonstrate that FAPs enhance angiogenesis of microvascular fragments (MVFs) by promoting increases in vessel percentage area and ...
Christian M. Mendiondo +6 more
wiley +1 more source
Three‐dimensional bioprinting transforms breast cancer modeling from simple constructs into spatially organized, multicellular, perfused, and patient‐derived platforms. This review shows how bioinks, cellular composition, architecture, and flow govern tumor behavior and drug response, while revealing why complexity alone is insufficient without ...
Mustafa Nakipoglu +7 more
wiley +1 more source
Fibroblast Activation Protein (FAP) has emerged as a critical player in cancer biology, particularly in shaping the tumour microenvironment (TME) and influencing immunotherapy outcomes.
Hsing Hwa Lee, Zeyad Al-Ogaili
doaj +1 more source
In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor +11 more
wiley +1 more source
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang +19 more
wiley +1 more source
A review of the development and research progress of FAPI PET probes
The application of fibroblast activation protein (FAP) in cancer-associated fibroblast (CAF) has garnered widespread attention in nuclear medicine. FAP is highly expressed in most cancer tissues and rarely expressed in healthy tissues.
CHENG Hua, BAI Liyan, SONG Shaoli
doaj
Background Fibroblast activation protein alpha (FAP) is a serine protease that is expressed at basal levels in benign tissues but is overexpressed in a variety of pathologies, including cancer.
Abdelrahman Homedan +3 more
doaj +1 more source
Synthesis, radiolabeling, and evaluation of a (4-quinolinoyl)glycyl-2-cyanopyrrolidine analogue for fibroblast activation protein (FAP) PET imaging. [PDF]
Zhang N +10 more
europepmc +1 more source

