Results 11 to 20 of about 5,314 (149)

Collectins and ficolins in neonatal health and disease. [PDF]

Front Immunol, 2023
Cedzyński M, Świerzko AS.
europepmc   +3 more sources

Exploring complement biomarkers in suspected axial spondyloarthritis [PDF]

RMD Open
Objectives To investigate lectin pathway proteins (LPPs) as biomarkers for axial spondyloarthritis (axSpA) in a cross-sectional cohort with a suspicion of axSpA, comprising newly diagnosed axSpA and chronic low back pain (cLBP) individuals.Methods Serum ...
Joachim Sieper, Denis Poddubnyy, Anne Gitte Loft, Anne Troldborg, Fabian Proft, Mikhail Protopopov, Valeria Rios Rodriguez, Judith Rademacher, Steffen Thiel, Burkhard Muche, Susanne Lüders, Laura Spiller, Anne-Katrin Weber, Clara Elbæk Mistegård   +13 more
doaj   +2 more sources

Ficolin-A Enhances Inhibition of the C-Terminal 19 kDa Region of Merozoite Surface Protein-1 of Plasmodium berghei Using Test In Vivo

Iranian Journal of Parasitology, 2013
Background: Malaria remains a serious public health problem with significant morbidity and mortal-ity. This study was conducted to identify whether ficolin-A could play an active role of against mala-ria infection.
F Chen, Q Liu, Y Xue, Yh Huang, Fy Huang, Y Lin, Gh Tan, J Zhou   +7 more
doaj   +3 more sources

Association of ficolin single nucleotide polymorphism with systemic lupus erythematosus in the Chinese Han Population. [PDF]

Rheumatol Immunol Res
Yin F, Gu J, Zhao P, Chen J.
europepmc   +2 more sources

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Association between serum ficolin-1 level and disease progression in primary biliary cholangitis

PLoS ONE, 2020
Pattern recognition molecules (PRMs) in the complement system contribute to homeostasis as mediators of complement activation. The contribution of PRMs to primary biliary cholangitis (PBC) is unknown.
Manabu Hayashi, Kazumichi Abe, Masashi Fujita, Atsushi Takahashi, Hideharu Sekine, Hiromasa Ohira, Aftab A. Ansari   +6 more
doaj   +2 more sources

Ficolin-2 defends against virulent Mycobacteria tuberculosis infection in vivo, and its insufficiency is associated with infection in humans. [PDF]

PLoS ONE, 2013
Human ficolin-2 (ficolin-2/P35) is a lectin complement pathway activator that is present in normal human plasma and is associated with infectious diseases; however, little is known regarding the roles and mechanisms of ficolin-2 during Mycobacterium ...
Fengling Luo, Xiaoming Sun, Yubin Wang, Qilong Wang, Yanhong Wu, Qin Pan, Chao Fang, Xiao-Lian Zhang   +7 more
doaj   +1 more source

Association between the Presence of Autoantibodies Targeting Ficolin-3 and Active Nephritis in Patients with Systemic Lupus Erythematosus. [PDF]

PLoS ONE, 2016
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of multiple autoantibodies. Antibodies against Ficolin-3 were previously identified in the sera of some SLE patients, but their prevalence and significance
Maëlle Plawecki, Elise Lheritier, Giovanna Clavarino, Noémie Jourde-Chiche, Saber Ouili, Stéphane Paul, Evelyne Gout, Françoise Sarrot-Reynauld, Nathalie Bardin, Pierre-Yves Boëlle, Laurent Chiche, Laurence Bouillet, Nicole M Thielens, Jean-Yves Cesbron, Chantal Dumestre-Pérard   +14 more
doaj   +1 more source

Association of ficolin-3 with severity and outcome of chronic heart failure. [PDF]

PLoS ONE, 2013
BACKGROUND: Inflammatory mechanisms involving complement activation has been shown to take part in the pathophysiology of congestive heart failure, but the initiating mechanisms are unknown. We hypothesized that the main initiator molecules of the lectin
Zoltán Prohászka, Lea Munthe-Fog, Thor Ueland, Timea Gombos, Arne Yndestad, Zsolt Förhécz, Mikkel-Ole Skjoedt, Zoltan Pozsonyi, Alice Gustavsen, Lívia Jánoskuti, István Karádi, Lars Gullestad, Christen P Dahl, Erik T Askevold, George Füst, Pål Aukrust, Tom E Mollnes, Peter Garred   +17 more
doaj   +1 more source