In vitro activity of eight antifungal drugs against clinical and hospital isolates of Candida parapsilosis complex; a multicenter study, 2023–2024 [PDF]
BMC Infectious DiseasesBackground Candida parapsilosis complex is an emerging opportunistic pathogen associated with bloodstream infections and healthcare‑associated outbreaks, particularly in intensive care units.
Azam Moslemi +13 more
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Isolation of a multidrug-resistant Candida auris Clade V from an asymptomatic acute myeloid leukemia patient in the intensive care unit [PDF]
Medical Mycology Case ReportsCandida auris is a multidrug-resistant fungal pathogen, that rapidly spreads within healthcare settings. Here, an acute myeloid leukemia patient undergoing chemotherapy was admitted to the intensive care unit. From the skin, C.
Azam Moslemi +8 more
doaj +2 more sources
Emergence of multidrug-resistant Candidozyma auris in southern China: a multicenter study on genetic diversity and antifungal resistance [PDF]
Frontiers in MicrobiologyPurposeCandidozyma auris (C. auris) is an emerging fungal pathogen that is resistant to multiple drugs and poses a serious threat to global health. This study aimed to investigate the genetic diversity and antifungal resistance profiles of C.
Penghao Guo +9 more
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Upc2A transcriptionally regulates FKS1 expression.
, 2021 A. An isogenic series of strains with the listed UPC2A genotypes was tested for resistance to the indicated stress agents that affect the cell wall. Strains were grown to mid-log phase and then serially diluted across each plate. Caspofungin was included
Bao Gia Vu (11507192) +4 more
core +1 more source
Pharmaceutics, 2023 Candida auris is a multidrug-resistant pathogen against which echinocandins are the drug of choice. However, information on how the chitin synthase inhibitor nikkomycin Z influences the killing activities of echinocandins against C.
Awid Adnan +9 more
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Analysis of molecular resistance to azole and echinocandin in Candida species in patients with vulvovaginal candidiasis [PDF]
Current Medical Mycology, 2022 Background and Purpose: Vulvovaginal candidiasis (VVC) is considered the most common mucosal infection caused by Candida species. Azoles were considered the firstline treatment for VVC or recurrent vulvovaginal candidiasis (RVVC) in both healthy and ...
Ensieh Lotfali +5 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Diutina catenulata (Candida catenulata) is an ascomycete yeast species widely used in environmental and industrial research and capable of causing infections in humans and animals. At present, there are only a few studies on D.
Xin-Fei Chen +37 more
doaj +1 more source
Journal of Fungi, 2020 Candida auris is an emerging multi-drug resistant pathogen with high mortality rate; nosocomial infections have been reported worldwide, causing a major challenge for clinicians and microbiological laboratories. The study aims to describe new cases of C.
Reem AlJindan +6 more
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Engineering the TetO System to Test the Contribution of FKS1 to Yeast Cell Wall Strength [PDF]
, 2021 Society has a demand for manufactured proteins such as insulin, which can be produced by the yeast Saccharomyces cerevisiae, but such proteins are not easily accessible due to this yeast’s rigid cell wall. I hypothesize that if S.
Jenkins, Steffany
core
Effect of Conformational Variability on the Drug Resistance of Candida auris ERG11p and FKS1
ACS OmegaCandida auris infection has been recognized as an urgent threat to antifungal drug resistance, and the Eagle effect of C. auris FKS1 (1,3-β-d-glucan synthase) wild-type isolates has also been noted.
Hiroshi Izumi +2 more
doaj +2 more sources