Results 191 to 200 of about 7,181 (257)

Redundant and Flexible Electron Transfer Pathways Underlie MsrPQ‐Mediated Repair of Oxidized Periplasmic Proteins

Molecular Microbiology, Volume 125, Issue 6, Page 493-505, June 2026.
This study investigates in vivo the role of the flavin reductase Fre as an electron supplier to the periplasmic methionine sulfoxide reductase system MsrPQ. ABSTRACT The MsrPQ system is essential for the repair of oxidized methionine residues in periplasmic proteins, ensuring bacterial resistance to oxidative stress and envelope integrity.
Laurent Loiseau, Benjamin Ezraty
wiley   +1 more source

Blue Light (λ = 453 nm) Significantly Reduces TGF-β-Induced Fibroblast Differentiation Through Reversible Disruption of Mitochondrial Respiration, Glycolysis, and ATP Production Rate. [PDF]

Biomedicines
Steentjes P, Krassovka J, Suschek CV, Maus U, Oezel L.   +4 more
europepmc   +1 more source

Beyond red/far‐red sensing: phytochrome perception of the marine light field by microalgae

New Phytologist, Volume 250, Issue 5, Page 2837-2844, June 2026.
Summary Phytochromes (PHYs) are a major group of photoreceptors, described as red and far‐red light sensors in land plants. Recent genomic and metagenomic explorations have revealed the presence of PHYs also in various eukaryotic microalgae originating from distinct endosymbiotic events.
Carole Duchêne, Marianne Jaubert, Angela Falciatore   +2 more
wiley   +1 more source

Fluorescein-based dyes are not valid reporters of oxidative stress in bacteria, and conclusions based on their use must be reconsidered. [PDF]

Proc Natl Acad Sci U S A
Korshunov S, Imlay JA.
europepmc   +1 more source

Molecular Clocks in Translational Roadmap for Circadian‐Based Therapeutics in Lung Diseases

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
High‐amplitude circadian oscillations maintain lung immune and epithelial homeostasis. Chronic inflammation dampens peripheral clock amplitude, driving chronodisruption, barrier dysfunction, and remodeling. Clock‐targeted therapies re‐entrain the lung circadian clock, restore rhythmic immune resolution, and promote functional lung repair.
Kingshuk Panda, Renu Khasa, Srinivasan Chinnapaiyan, Saurabh Aggarwal, Irfan Rahman, Hoshang Unwalla   +5 more
wiley   +1 more source

Multispectral Imaging of Collagen, NAD(P)H and Flavin Autofluorescence in Mesenchymal Stem Cells Undergoing Trilineage Differentiation. [PDF]

Cells
Campbell JM, Mahbub SB, Anwer AG, Habibalahi A, Gronthos S, Paton S, Grey ST, Wu LE, Gilchrist RB, Goldys EM.   +9 more
europepmc   +1 more source

Identification of 2‐Substituted‐3‐Hydroxy‐2,3‐Dihydroquinazolin‐4(1H) Ones as Cell‐Active Inhibitors of KDM4A Lysine Demethylase

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
A novel 3‐hydroxy‐2,3‐dihydroquinazolinone scaffold is identified as a cell‐active KDM4A inhibitor through an orthogonal screening cascade minimizing assay interference. Integrated biochemical, biophysical, and proteomic validation reveals compound 6i as a bona fide binder that increases H3K9 methylation in cells, highlighting both a promising ...
Alessandra Feoli, Amodio Luca Balzano, Ida Pacilio, Alessandra Cipriano, Roman Belle, Giacomo Pepe, Manuela Giovanna Basilicata, Pietro Campiglia, Fabrizio Micheli, Akane Kawamura, Ciro Milite, Sabrina Castellano, Axel Imhof, Gianluca Sbardella   +13 more
wiley   +1 more source

Electrochemical Observation and pH Dependence of All Three Expected Redox Couples in an Extremophilic Bifurcating Electron Transfer Flavoprotein with Fused Subunits. [PDF]

JACS Au
Das D, El Housseini W, Brachi M, Minteer SD, Miller AF.   +4 more
europepmc   +1 more source

Reprogramming <i>Listeria monocytogenes</i> flavin metabolism to improve its therapeutic safety profile and broaden innate T-cell activation. [PDF]

mBio
Chevée V, Lobanovska M, Rivera-Lugo R, Güereca L, Feng Y, Anaya-Sanchez A, Garcia Castillo J, Huckins AM, Lemmens EE, Rae CS, Hardy JW, Carrington R, Kotula JW, Portnoy DA.   +13 more
europepmc   +1 more source

Sensing the Reducing Power to Determine the Cell Fate: Flavin Redox-Switches in Signal Transduction. [PDF]

Curr Microbiol
Scribani-Rossi C, Angeli S, Paone A, Spizzichino S, Di Fonzo F, Arese M, Cutruzzolà F, Paiardini A, Rinaldo S.   +8 more
europepmc   +1 more source