Results 201 to 210 of about 7,338 (299)

Avoidance of MAIT cells is an essential determinant of <i>Listeria</i> monocytogenes pathogenesis. [PDF]

Proc Natl Acad Sci U S A
Rivera-Lugo R, Garcia Castillo J, Lobanovska M, Tang E, Anaya-Sanchez A, Espich S, Stanley SA, DuPage M, Portnoy DA.   +8 more
europepmc   +1 more source

Are Less Affluent People Less Likely to Run for Political Office?

Swiss Political Science Review, EarlyView.
Abstract In almost all democracies, elected officials are better off than most of the citizens they represent. Recent research has shown that this descriptive misrepresentation is partly due to voter and party bias against less well‐off candidates. In this paper, we explore a third possible explanation: Are less affluent people less likely to run for ...
Pirmin Bundi, Reto Wüest
wiley   +1 more source

Linear free energy relationship between reduction potential and photoreduction rate: studies on Drosophila cryptochrome. [PDF]

FEBS J
Okasha M, Chen J, Ayekoi A, Jacob E, Radtke V, Schmidt A, Bacher A, Weber S, Schleicher E.   +8 more
europepmc   +1 more source

Transglucosidation reactions with flavins [PDF]

Biochemical Journal, 1954
openaire   +2 more sources

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

Iron reduction under oxic conditions by Microbacterium deferre sp. nov. A1-JK^T. [PDF]

Nat Commun
Lustermans JJM, Basu N, Digel L, Aiyer K.   +3 more
europepmc   +1 more source

Developmental riboflavin deficiency results in structural and functional changes in the neural retina and RPE. [PDF]

Redox Biol
Zhao X, Makia MS, Naash MI, Al-Ubaidi MR.   +3 more
europepmc   +1 more source

Oxidative and Antioxidant Systems in Ferroptosis of Cancer: Mechanisms, Regulations, and Therapeutic Targeting

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Ferroptosis is governed by the balance between reactive oxygen species (ROS)‐driven lipid peroxidation and a multi‐tiered antioxidant network. ROS sources include mitochondrial electron transport chain, voltage‐dependent anion channels, NADPH oxidases, and endoplasmic reticulum‐resident oxidoreductases, while antioxidant defenses span the primary GSH ...
Deepak K, Pritam Kumar Roy, Maniklal Shee, Budhaditya Mukherjee, Aoife Ward Gahlawat, Mahitosh Mandal   +5 more
wiley   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2764-2776, August 2026.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf, Ymke van der Velde, Paul R. V. Malik, Jelmer R. Prins, Sanne J. Gordijn, Daan J. Touw, Paola Mian   +6 more
wiley   +1 more source

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 313-323, August 2026.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory, Gonzalo Villapalos Garcia, Dora Koller, Solomon Adams, Chad A. Bousman, Evangelia Eirini Tsermpini, Michelle Whirl‐Carrillo, Amy J. Turner, Volker M. Lauschke, Mohamed Nagy, Erin C. Boone, Teri E. Klein, Pablo Zubiaur, Andrea Gaedigk   +13 more
wiley   +1 more source