Results 211 to 220 of about 7,338 (299)
Engineering Alloxazines by Boron Coordination and Click Chemistry toward Small-molecule Fluorescent Probes. [PDF]
Charpentier O +5 more
europepmc +1 more source
ABSTRACT A focused library of 19 donepezil‐linked chalcones (DLCs) was efficiently synthesised through microwave‐assisted Claisen‐Schmidt condensation and subsequently profiled for their inhibitory activities against cholinesterases (AChE and BuChE) as well as monoamine oxidases (MAO‐A and MAO‐B).
Azize Kirac‐Aydin +11 more
wiley +1 more source
Overlap and differences between the inward and outward electron transfer pathways in Shewanella oneidensis. [PDF]
Ford KC +3 more
europepmc +1 more source
Miniaturized Droplet‐Based Adaptation of the Ames Test for High‐Throughput Mutagenicity Assessment
ABSTRACT This work presents the first demonstration of a tube‐based droplet microfluidic implementation of the Ames test, bridging single‐droplet resolution with regulatory genotoxicity testing. The Ames test is a cornerstone assay for detecting mutagenicity, but conventional plate‐ and well‐based formats suffer from high reagent consumption, low ...
Jialan Cao +3 more
wiley +1 more source
Wavelength-Dependent Modulation of Mesenchymal Stem Cell Fate: A Systems Biology Framework for Tissue Repair and Regenerative Medicine. [PDF]
Amouroux B +6 more
europepmc +1 more source
Metabolic Regulation of Macrophages in Health and Disease
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang +6 more
wiley +1 more source
Identification of colorectal malignancies enabled by phasor-based autofluorescence lifetime macroimaging and ensemble learning. [PDF]
Lagarto JL +10 more
europepmc +1 more source
ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source

