Results 171 to 180 of about 37,339 (280)

Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan

Aging Cell, Volume 25, Issue 10, October 2026.
Phenotypic screening and SAR‐guided drug design identified two flavonoid‐derived senolytics, SR29384 and SR31133, which selectively killed different types of senescent cells more efficiently and with greater selectivity than fisetin in culture. In aged and progeroid mice, these fisetin analogs reduced tissue senescence and improved physical function ...
Lei Justan Zhang, Rahagir Salekeen, Carolina Soto‐Palma, Qiuming Wu, Yuanjun He, Osama Elsallabi, Bilel Bdiri, Brian Hughes, Allancer Nunes, Wandi Xu, Borui Zhang, Abdalla Mohamed, Sara J. McGowan, Luise Angelini, Ryan O'Kelly, Theodore M. Kamenecka, Laura J. Niedernhofer, Paul D. Robbins   +17 more
wiley   +1 more source

Polyphenols from Pulses: Recent Advances in Gut Health Benefits and Strategies to Elevate Their Concentrations. [PDF]

Nutrients
Wang J, Wei R, Wang J, Bai T, Jiang X, Zhou S, Hou D.   +6 more
europepmc   +1 more source

Comprehensive Mass Balance of Pilot‐Scale Apple Juice Production Using Sequential Dual‐Enzyme Treatments

Journal of Food Process Engineering, Volume 49, Issue 10, October 2026.
A component‐resolved mass balance of pilot‐scale apple juice production demonstrated that sequential cellulolytic maceration and PME‐mediated clarification synergistically increased yield to 65% with 71.7% polyphenol retention, while bound‐to‐free polyphenol fractionation confirmed enzymatic liberation of matrix‐bound phenolics during clarification—a ...
Ilyes Dammak, Carlos Adam Conte‐Junior
wiley   +1 more source

Distinct metabolic architectures differentiate HLB-tolerant lemon and susceptible sweet orange. [PDF]

Front Plant Sci
Gomes P, Cheng B, Laffitte B, Bilal MS, Aslam MN, Chen Q, Wei T, Zhao H.   +7 more
europepmc   +1 more source

A TAF10‐ERF109 Transcriptional Module Directs Flavonoid‐Based Stress Resilience and Yield Enhancement in Foxtail Millet and Wheat

Plant Biotechnology Journal, Volume 24, Issue 10, Page 5352-5368, October 2026.
ABSTRACT To ensure sustainable agricultural production under escalating environmental constraints such as drought and salinity, innovative strategies are urgently needed. Here, we reveal in foxtail millet (Setaria italica) that transcription factors TAF10 and ERF109 form a functional complex which co‐activates the expression of key flavonoid ...
Meng Zhang, Kangwei Wang, Jiayin Fan, Yue Zheng, Qi Zhang, Haoyang Du, Shenghui Xiao, Jinguang Huang, Kang Yan, Shizhong Zhang, Qiang He, Guanqing Jia, Chengchao Zheng, Xianmin Diao, Guodong Yang, Changai Wu   +15 more
wiley   +1 more source

Dietary pattern modifies associations between dietary factors and pace of epigenetic aging. [PDF]

Front Nutr
Ferreri DM, Lopez NV, Sutliffe JT, Sutliffe CA, Smith R, Carreras-Gallo N, Dwaraka VB, Seale K, Fuhrman JH.   +8 more
europepmc   +1 more source

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

Plant, Cell &Environment, Volume 49, Issue 10, Page 7435-7448, October 2026.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang, Fengjiao Wang, Ran Du, Tao Li, Shaoqun Zhou, Jianbin Yan, Wei Li   +6 more
wiley   +1 more source

Blackcurrant (<i>Ribes nigrum</i> L.) Matrices: Polyphenol Release, Antioxidant Capacity and Enzyme Inhibitory Potential. [PDF]

Antioxidants (Basel)
Szydłowska M, Wojdyło A, Nowicka P.
europepmc   +1 more source

Loss of DET1 in High Pigment 2 Tomato Prevents High Temperature Repression of Anthocyanin Biosynthesis in Fruit Through HY5 Stabilization

Plant, Cell &Environment, Volume 49, Issue 10, Page 7449-7469, October 2026.
ABSTRACT Global warming impacts several aspects of plant physiology, with important negative effects on crop yield and production of secondary metabolites, such as anthocyanins. The anthocyanin content of vegetables and fruits has attracted public interest in the last two decades due to its health benefits, leading to the development of novel ...
Jacopo Menconi, Noemi La Monaca, Irene Cataldo, Pietro Maria Niccolini, Pierdomenico Perata, Silvia Gonzali   +5 more
wiley   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, Volume 49, Issue 10, Page 7558-7574, October 2026.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source