Results 61 to 70 of about 74,405 (378)

Selected Flavonols Targeting Cell Death Pathways in Cancer Therapy: The Latest Achievements in Research on Apoptosis, Autophagy, Necroptosis, Pyroptosis, Ferroptosis, and Cuproptosis

open access: yesNutrients
The complex and multi-stage processes of carcinogenesis are accompanied by a number of phenomena related to the potential involvement of various chemopreventive factors, which include, among others, compounds of natural origin such as flavonols.
Dominika Wendlocha   +3 more
semanticscholar   +1 more source

Flavonols modulate lateral root emergence by scavenging reactive oxygen species in Arabidopsis thaliana

open access: yesbioRxiv, 2020
Flavonoids are plant-specific antioxidant compounds that modulate plant development, which include flavonols and anthocyanins subclasses. In Arabidopsis thaliana, mutants in genes encoding each step in the flavonoid biosynthetic pathway have been ...
Jordan M. Chapman, G. Muday
semanticscholar   +1 more source

Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes [PDF]

open access: yes, 2017
Cardiovascular diseases are the main cause of mortality and morbidity in the world. Hypertension, ischemia/reperfusion, diabetes and anti-cancer drugs contribute to heart failure through oxidative and nitrosative stresses which cause cardiomyocytes ...
Bei, Roberto   +10 more
core   +2 more sources

Methods of Protection/Deprotection of Hydroxy Groups in the Synthesis of Polyhydroxy Flavonols

open access: yesВісник Харківського національного університету: Серія xімія
The article represents a review of methods for obtaining polyhydroxy flavonols without protection of hydroxy groups, as well as syntheses using methylation, alkylation and benzylation of the initial reagents and, accordingly, demethylation, dealkylation ...
Oleksii Demidov, Alexander Roshal
doaj   +1 more source

Flavonols control pollen tube growth and integrity by regulating ROS homeostasis during high-temperature stress

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Plant sexual reproduction is required for seed and fruit production and is highly sensitive to elevated temperatures, suggesting that climate change may have profound agricultural impacts through inhibition of this process.
Joëlle K. Muhlemann   +2 more
semanticscholar   +1 more source

Pretreatment of citrus by-products affects polyphenol recovery:a review [PDF]

open access: yes, 2018
A large amount of citrus waste is generated annually. This waste is of great economic worth, since it contains high levels of polyphenols, which have attracted scientific interest due to their potent antimicrobial and antiradical activities. Pretreatment
Bowyer, Michael C.   +7 more
core   +2 more sources

Antioxidant and Antiglycation Effects of Cistus × incanus Water Infusion, Its Phenolic Components, and Respective Metabolites

open access: yesMolecules, 2022
Reactive oxygen and carbonyl species promote oxidative and carbonyl stress, and the development of diabetes, metabolic syndrome, cardiovascular diseases, and others. The traditional herb Cistus × incanus is known for its antioxidant properties; therefore,
Karolina Bernacka   +4 more
doaj   +1 more source

Interaction Mechanism between OVA and Flavonoids with Different Hydroxyl Groups on B-Ring and Effect on Antioxidant Activity

open access: yesFoods, 2022
Ovalbumin (OVA) is a common carrier with high efficiency to deliver flavonoids. The aim of this study was to investigate the interaction mechanism of OVA and four flavonoids (quercetin (Que), myricetin (Myri), isorhamnetin (Ish), and kaempferol (Kaem ...
Wenna Zhou   +5 more
doaj   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

open access: yesAdvanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan   +12 more
wiley   +1 more source

Analysis of the flavonoid component of bioactive New Zealand mānuka (Leptospermum scoparium) honey and the isolation, characterisation and synthesis of an unusual pyrrole [PDF]

open access: yes, 2013
The flavonoid components of New Zealand mānuka (Leptospermum scoparium) honey have been quantified in a series of 31 honeys of varying non-peroxide antibacterial activity to clarify discrepancies between previous studies reported in the literature. Total
Alber, Dagmar G.   +5 more
core   +2 more sources

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