Results 41 to 50 of about 253,632 (296)

Follicular regulatory T cell in atherosclerosis [PDF]

Journal of Leukocyte Biology, 2018
Abstract Atherosclerosis is a chronic inflammatory disease involving the infiltration of immune cells, such as monocytes/macrophages, neutrophils, T cells, and B cells, into the inner layer of vessel walls. T and B cell functions in the process of atherogenesis, as well as their mutual regulation, have been investigated but several ...
Baptista, Daniela, Mach, François, Brandt, Karim   +2 more
openaire   +4 more sources

Follicular Regulatory T Cells Are Highly Permissive to R5-Tropic HIV-1 [PDF]

J Virol, 2017
Shannon M Miller, B. Miles, K. Guo, J. Folkvord, Amie L Meditz, M. McCarter, D. N. Levy, S. MaWhinney, M. Santiago, E. Connick   +9 more
semanticscholar   +2 more sources

Characterization of T Follicular Helper Cells and T Follicular Regulatory Cells in HIV-Infected and Sero-Negative Individuals

Cells, 2023
Humoral immune response is important in fighting pathogens by the production of specific antibodies by B cells. In germinal centers, T follicular helper (TFH) cells provide important help to B-cell antibody production but also contribute to HIV ...
Bradley Salvatore, Rachel S. Resop, Brent R. Gordon, Marta Epeldegui, Otoniel Martinez-Maza, Begoña Comin-Anduix, Alex Lam, Ting-Ting Wu, Christel H. Uittenbogaart   +8 more
doaj   +1 more source

T follicular helper cells, T follicular regulatory cells and autoimmunity [PDF]

International Immunology, 2015
Abstract CD4 + T follicular helper (Tfh) cells are recognized as a distinct T-cell subset, which provides help for germinal center (GC) formation, B-cell development and affinity maturation, and immunoglobulin class switching, as an indispensable part of adaptive immunity.
Yangyang, Zhu, Le, Zou, Yun-Cai, Liu
openaire   +2 more sources

The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood

Nature Immunology, 2012
P. Sage, Loise M. Francisco, C. Carman, A. Sharpe   +3 more
semanticscholar   +3 more sources

Highly sensitised individuals present a distinct Treg signature compared to unsensitised individuals on haemodialysis

Frontiers in Transplantation, 2023
IntroductionHighly sensitised (HS) patients represent up to 30% of patients on the kidney transplant waiting list. When they are transplanted, they have a high risk of acute/chronic rejection and long-term allograft loss.
C. Dudreuilh, C. Dudreuilh, S. Basu, S. Basu, O. Shaw, H. Burton, H. Burton, N. Mamode, N. Mamode, F. Harris, T. Tree, P. Nedyalko, M. Terranova-Barberio, G. Lombardi, C. Scottà, A. Dorling, A. Dorling   +16 more
doaj   +1 more source

Altered Distribution of Circulating T Follicular Helper-Like Cell Subsets in Rheumatoid Arthritis Patients

Frontiers in Medicine, 2021
Objective: Recent studies on follicular regulatory T (Tfr) and follicular helper T (Tfh) cells suggest that they may participate in the pathogenesis of rheumatoid arthritis (RA).
Rui Su, Yanyan Wang, Fangyuan Hu, Baochen Li, Qiaoling Guo, Xinyu Zheng, Yue Liu, Chong Gao, Xiaofeng Li, Caihong Wang   +9 more
doaj   +1 more source

T follicular regulatory cells in mice and men [PDF]

Immunology, 2017
SummaryIt has long been known that CD4 T cells are necessary to provide help to B cells, triggering a germinal centre (GC) reaction where affinity maturation and isotype switching occur. However, the nature of the dedicated CD4 helper T cells, known as T follicular helper (Tfh), was only recently described.
Ana Raquel Maceiras, Valter R. Fonseca, Ana Agua‐Doce, Luis Graca   +3 more
openaire   +2 more sources

Impaired function of PD‐1+ follicular regulatory T cells in systemic lupus erythematosus

Clinical and Experimental Immunology, 2021
Aberrant autoantibody production is characteristic of systemic lupus erythematosus (SLE), but follicular regulatory T (TFR) cells can potentially suppress this abnormality. We investigate functional changes in TFR cells from SLE patients. Circulating TFR
I. Kurata, Natsuko Mikami, A. Ohyama, A. Osada, Y. Kondo, H. Tsuboi, T. Sumida, I. Matsumoto   +7 more
semanticscholar   +1 more source

Deficiency in T follicular regulatory cells promotes autoimmunity [PDF]

Journal of Experimental Medicine, 2018
T follicular regulatory (Tfr) cells are a new subset of regulatory T (T reg) cells localized in the germinal center to limit the humoral response. Until now, the physiological function of Tfr cells has been largely unknown. In this study, we developed a Bcl6fl/flFoxp3Cre mouse to analyze the function of Tfr cells in immune and autoimmune responses ...
Weiwei Fu, Xindong Liu, Xiang Lin, Han Feng, Lin Sun, Shuran Li, Hairong Chen, Hong Tang, Liwei Lu, Wei Jin, Chen Dong   +10 more
openaire   +2 more sources