Results 11 to 20 of about 867,229 (232)

DIP2 disco‐interacting protein 2 homolog A (Drosophila) is a candidate receptor for follistatin‐related protein/follistatin‐like 1 – analysis of their binding with TGF‐β superfamily proteins [PDF]

The FEBS Journal, 2010
Follistatin‐related protein (FRP)/follistatin‐like 1 (FSTL1) is a member of the follistatin protein family, all of which share a characteristic structure unit found in follistatin, called the FS domain. Developmental studies have suggested that FRP regulates organ tissue formation in embryos.
Masao, Tanaka, Kosaku, Murakami, Shoichi, Ozaki, Yoshitaka, Imura, Xiao-Peng, Tong, Takuo, Watanabe, Toshioki, Sawaki, Takafumi, Kawanami, Daisuke, Kawabata, Takao, Fujii, Takashi, Usui, Yasufumi, Masaki, Toshihiro, Fukushima, Zhe-Xiong, Jin, Hisanori, Umehara, Tsuneyo, Mimori   +15 more
openaire   +3 more sources

Follistatin as potential therapeutic target in prostate cancer [PDF]

Targeted oncology, 2013
Follistatin is a single-chain glycosylated protein whose primary function consists in binding and neutralizing some members of the transforming growth factor-β superfamily such as activin and bone morphogenic proteins.
CRESCIMANNO, Marilena, DI MAJO, Danila, FLANDINA, Carla, GIAMMANCO, Marco, LA GUARDIA, Maurizio, LETO, Gaetano, Sepporta, MV, TUMMINELLO, Francesca Maria   +7 more
core   +2 more sources

Circulating organokines in coronary artery disease and metabolic syndrome: FABP4, adiponectin, irisin, FSTL1 [PDF]

Biomolecules & Biomedicine
Cardiovascular disorders are closely linked to metabolic syndrome and remain a leading cause of mortality worldwide, despite advances in early detection and treatment.
Meltem Uyaner Kan, İbrahim Kilinc, Hakan Akilli, Hasan Huseyin Bilgic   +3 more
doaj   +2 more sources

FSTL-1 as a Novel Cardiokine of Cardiac Angiogenesis: A Systematic Review [PDF]

Vascular Health and Risk Management
Putri Karisa,1 Nova Sylviana,2– 4 Nita Fitria,4,5 Setiawan Setiawan2– 4 1Biomedical Science Master Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Department of Biomedical Science, Faculty of Medicine, Universitas ...
Karisa P, Sylviana N, Fitria N, Setiawan S   +3 more
doaj   +2 more sources

Evaluation of Metabolism-Associated Proteins in Abdominal Aortic Aneurysm.

J Vasc Res
Introduction: Abdominal aortic aneurysm (AAA) development is inversely associated with diabetes mellitus. Targeting glucose metabolism seems to be a beneficial strategy for preventing AAA growth. Several metabolism-related factors are associated with AAA
Ramilo AB, Chandrinos N, Tsichlia E, Jönsson J, Mani K, Wanhainen A, Wågsäter D.   +6 more
europepmc   +2 more sources

Human Follistatin-Related Protein: A Structural Homologue of Follistatin with Nuclear Localization [PDF]

Endocrinology, 2001
Follistatin-related protein is a recently discovered glycoprotein that is highly homologous in both primary sequence and exon/intron domain structure to the activin-binding protein, follistatin. We explored their potential for functional redundancy by investigating the relative affinities and kinetics of their interactions with activin, bone ...
D V, Tortoriello, Y, Sidis, D A, Holtzman, W E, Holmes, A L, Schneyer   +4 more
openaire   +3 more sources

Follistatin-Related Protein and Follistatin Differentially Neutralize Endogenous vs. Exogenous Activin [PDF]

Endocrinology, 2002
Follistatin-related protein (FSRP) is a new addition to the expanding follistatin (FS)-related gene family whose members contain at least one conserved 10-cysteine follistatin domain. In contrast to other members of this family, FSRP and follistatin also share a common exon/intron domain structure, substantial primary sequence homology, and an ability ...
Yisrael, Sidis, Drew V, Tortoriello, William E, Holmes, Yang, Pan, Henry T, Keutmann, Alan L, Schneyer   +5 more
openaire   +3 more sources

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Identification of Differential Expression Cytokines in Hemolysis, Elevated Liver Enzymes, and Low Platelet Syndrome by Proteome Microarray Analysis and Further Verification

Cell Transplantation, 2021
To screen the differential expression cytokines (DECs) in hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome, establish its differential cytokines spectra, and provide the clues for its diagnosis and pathogenic mechanism researches ...
Suya Kang, Liping Zhou, Yun Wang, Hui Li, Hong Zhang   +4 more
doaj   +1 more source

Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases [PDF]

International Immunology, 1998
In an attempt to identify autoantigens of synovium in rheumatoid arthritis (RA), we constructed lambda phage expression cDNA libraries from synovium and screened them by IgG purified from synovial fluids, both of which were derived from RA patients.
M, Tanaka, S, Ozaki, F, Osakada, K, Mori, M, Okubo, K, Nakao   +5 more
openaire   +2 more sources