Results 11 to 20 of about 12,023,937 (197)

Expression patterns of follistatin and two follistatin-related proteins during mouse development [PDF]

The International Journal of Developmental Biology, 2000
We compared the expression patterns of follistatin and two follistatin-related proteins (FRP and m7365) during early mouse development. m7365 is expressed continuously during preimplantation development, in contrast to FRP and follistatin. At early postimplantation stages, follistatin and 7365 are expressed from E6.0, while FRP is detected from E7.5 ...
Groot, E. de, Feijen, A., Eib, D.W., Zwijsen, A., Sugino, H., Martens, G.J.M., Eijnden-van Raaij, A.J.M. van den   +6 more
core   +5 more sources

Sheng-ji Hua-yu formula promotes diabetic wound healing of re-epithelization via Activin/Follistatin regulation

BMC Complementary and Alternative Medicine, 2018
Background Sheng-ji Hua-yu(SJHY) formula is one of the most useful Traditional Chinese medicine (TCM) in the treatment of the delayed diabetic wound.
Le Kuai, Jing-ting Zhang, Yu Deng, Shun Xu, Xun-zhe Xu, Min-feng Wu, Dong-jie Guo, Yu Chen, Ren-jie Wu, Xing-qiang Zhao, Hua Nian, Bin Li, Fu-lun Li   +12 more
doaj   +2 more sources

Differential expression of follistatin and FLRG in human breast proliferative disorders [PDF]

BMC Cancer, 2009
Background Activins are growth factors acting on cell growth and differentiation. Activins are expressed in high grade breast tumors and they display an antiproliferative effect inducing G0/G1 cell cycle arrest in breast cancer cell lines.
Amaral Vania F, Grasso Giovanni, Muscettola Michela, Borges Lavinia E, Mencarelli Marzia, Ciarmela Pasquapina, Massai Lauretta, Couto Henrique L, Bloise Enrrico, Cassali Geovanni D, Petraglia Felice, Reis Fernando M   +11 more
doaj   +3 more sources

Characterization of a Rat C₆ Glioma‐Secreted Follistatin‐Related Protein (FRP) [PDF]

European Journal of Biochemistry, 1994
A protein was isolated from rat C6 glioma‐conditioned medium and was biochemically characterized. The heparin‐binding protein has a native molecular mass of 55–75000Da, a molecular mass of 40–48000 Da under denaturing conditions, and a pI of 5.0–6.0. Based on the determined partial amino acid sequences, the full lenght cDNA encoding the rat and human ...
Zwijsen, An, Blockx, Herman, Van Arnhem, Wouter, Willems, Jean, Fransen, Lucie, Devos, Kathleen, Raymackers, Jos, Van de Voorde, André, Slegers, H.   +8 more
openaire   +4 more sources

The Non-Linear Profile of Aging: U-Shaped Expression of Myostatin, Follistatin and Intermediate Signals in a Longitudinal In Vitro Murine Cell Sarcopenia Model

Proteomes
Sarcopenia is linked to the decline in muscle mass, strength and function during aging. It affects the quality and life expectancy and can lead to dependence.
Janire Alonso-Puyo, Oihane Izagirre-Fernandez, Olatz Crende, Jesús Seco-Calvo, Ainhoa Fernandez-Atutxa, Diego Fernandez-Lazaro, Patricia Garcia-Gallastegi, Begoña Sanz   +7 more
doaj   +2 more sources

Maternal Serum Activin A, Inhibin A and Follistatin-Related Proteins across Preeclampsia: Insights into Their Role in Pathogenesis and Prediction. [PDF]

J Mother Child, 2023
Within the endocrine-paracrine signalling network at the maternal-foetal interface, the activin-inhibin-follistatin system modulates extravillous trophoblast invasion, suggesting a potential role in preeclampsia pathogenesis. This study aimed to compile the evidence published in the last decade regarding the variation in maternal serum activins ...
Barrero JA, Villamil-Camargo LM, Imaz JN, Arciniegas-Villa K, Rubio-Romero JA.   +4 more
europepmc   +3 more sources

Evaluation of Associations of Growth Differentiation Factor-11, Growth Differentiation Factor-8, and Their Binding Proteins, Follistatin and Follistatin-Like Protein-3, With Measures of Skeletal Muscle Mass, Muscle Strength, and Physical Function in Older Adults. [PDF]

, 2023
BACKGROUND: Based on studies from animal models, growth differentiation factor-11 (GDF-11) may have rejuvenating effects in humans. GDF-11 has high sequence homology with GDF-8 (also known as myostatin); follistatin and follistatin-like protein-3 (FSTL-3)
Bhasin, Shalender, Kizer, Jorge R, Patel, Sheena, Newman, Anne B, LeBrasseur, Nathan K, Cawthon, Peggy, Newman, Anne, Cawthon, Peggy M, Ganz, Peter, Peng, Liming, LeBrasseur, Nathan, Lee, Se-Jin, Cummings, Steven R, Tracy, Russell P, Tracy, Russell, Cummings, Steven, Kizer, Jorge, Ferrucci, Luigi, Luigi Ferrucci, Peter Ganz, Nathan K LeBrasseur, Anne B Newman, Jorge R Kizer, Se-Jin Lee, Liming Peng, Shalender Bhasin, Russell Tracy, Peggy M Cawthon, Steve Cummings, Sheena Patel   +29 more
core   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Hepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli, Silvia Marchianò, Cristina di Giorgio, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Bianca Fiorillo, Valentina Sepe, Bruno Catalanotti, Chiara Cassiano, Maria Chiara Monti, Eleonora Distrutti, Angela Zampella, Stefano Fiorucci   +13 more
wiley   +1 more source

Follistatin-Related Protein and Follistatin Differentially Neutralize Endogenous vs. Exogenous Activin [PDF]

Endocrinology, 2002
Follistatin-related protein (FSRP) is a new addition to the expanding follistatin (FS)-related gene family whose members contain at least one conserved 10-cysteine follistatin domain. In contrast to other members of this family, FSRP and follistatin also share a common exon/intron domain structure, substantial primary sequence homology, and an ability ...
Yisrael, Sidis, Drew V, Tortoriello, William E, Holmes, Yang, Pan, Henry T, Keutmann, Alan L, Schneyer   +5 more
openaire   +3 more sources

Cloning of follistatin-related protein as a novel autoantigen in systemic rheumatic diseases [PDF]

International Immunology, 1998
In an attempt to identify autoantigens of synovium in rheumatoid arthritis (RA), we constructed lambda phage expression cDNA libraries from synovium and screened them by IgG purified from synovial fluids, both of which were derived from RA patients.
M, Tanaka, S, Ozaki, F, Osakada, K, Mori, M, Okubo, K, Nakao   +5 more
openaire   +2 more sources