Results 91 to 100 of about 1,235 (162)

SYNTHESIS AND EVALUATION OF FOSMIDOMYCIN ANALOGUES AS ANTIMALARIAL AGENTS

, 2007
This Ph.D. study constitutes part of an extensive project dealing with the design and development of new agents with antimalarial activity. The enzyme 1-deoxy-D-xylulose-5-phosphate reductoisomerase (DXR), which is involved in the DOXP pathway for isoprenoid synthesis, was chosen as drug target.
openaire   +1 more source

Effects of copper and cadmium stress on resistance genes in farmland soil. [PDF]

BMC Microbiol
He R, Liu K, Yang F, Feng SQ, Zhang L.
europepmc   +1 more source

Mutations in apicoplast rRNA genes are associated with clindamycin resistance and impair the ability of malaria parasites to infect mosquitoes. [PDF]

Antimicrob Agents Chemother
Home JL, Yeoh LM, McFadden GI, Goodman CD.   +3 more
europepmc   +1 more source

The Fsr transporter of <i>Sinorhizobium meliloti</i> contributes to antimicrobial resistance and symbiosis with alfalfa. [PDF]

Microbiology (Reading)
Chávez-Jacobo VM, Reyes-González AR, Girard L, Dunn MF.   +3 more
europepmc   +1 more source

Comprehensive profiling of antibiotic resistance genes and functional clusters of orthologous groups annotation of gut microbiota in Indonesian Kedu chickens. [PDF]

J Genet Eng Biotechnol
Agusetyaningsih I, Lestari DA, Pandupuspitasari NS, Setiaji A, Philco SV, Sugiharto S.   +5 more
europepmc   +1 more source

Stable Isotopic Labeling of Dimethylallyl Pyrophosphate (DMAPP) Reveals Compartmentalization of Isoprenoid Biosynthesis during Sporulation in <i>Bacillus subtilis</i>. [PDF]

J Am Chem Soc
McBee DP, Hulsey ZN, Hedges MR, Baccile JA.   +3 more
europepmc   +1 more source

Structural diversity of isoprene synthases in mosses from multiple terpenoid synthase lineages. [PDF]

J Biol Chem
Kawakami T, Miyazaki S, Inoue Y, Kawaide H.   +3 more
europepmc   +1 more source

Longitudinal replicated metagenomic analysis of biosolids-amended soils reveals enrichment of ARGs, virulence factors, and ESKAPE pathogens. [PDF]

NPJ Antimicrob Resist
Ste Marie J, Mays C, Guo B, Radniecki TS, Waite-Cusic J, Navab-Daneshmand T.   +5 more
europepmc   +1 more source

Genomic and phenotypic insight into antimicrobial resistance of <i>Pseudomonas fluorescens</i> from King George Island, Antarctica. [PDF]

Front Microbiol
Silverio MP, Schultz J, Parise MTD, Parise D, Viana MVC, Nogueira W, Ramos RTJ, Góes-Neto A, Azevedo VAC, Brenig B, Bonelli RR, Rosado AS.   +11 more
europepmc   +1 more source

MEP Pathway: First-Synthesized IspH-Directed Prodrugs with Potent Antimycobacterial Activity. [PDF]

Microorganisms
Allamand A, Noël-Duchesneau L, Ettelbruck C, De Luna E, Lièvremont D, Grosdemange-Billiard C.   +5 more
europepmc   +1 more source