Results 81 to 90 of about 1,208 (158)

Coordinated carbon metabolite flux between the methyl erythritol phosphate (MEP) and the mevalonate (MVA) pathway regulates the withanolide biosynthesis in Withania somnifera (L.) Dunal

Discover Plants
Withanolides are bioactive triterpenoids that require isoprene units viz., isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) as precursor molecule for their biosynthesis, mediated via two independent routes, the plastidial methyl ...
Prince Choyal, Virendra Singh Rana, Maharishi Tomar, Kalidindi Usha, Bhupinder Singh   +4 more
doaj   +1 more source

The <i>Pseudomonas aeruginosa</i> DedA protein PA4029 is an undecaprenyl phosphate flippase important for polymyxin resistance. [PDF]

mBio
Sposato D, Wang Y, Zhang X, Rossi L, De Chiara S, Di Lorenzo F, Leoni L, Rampioni G, Visca P, Bolla JR, Imperi F.   +10 more
europepmc   +1 more source

Recent advances in natural and synthetic phosphonate therapeutics. [PDF]

Curr Opin Microbiol
Cui J, Ju KS.
europepmc   +1 more source

The early human interferon gamma response to Toxoplasma gondii is driven by Vγ9Vδ2 T-cell sensing of host phosphoantigens and subsequent NK-cell activation. [PDF]

PLoS Pathog
Rodriguez F, Saeij JPJ.
europepmc   +1 more source

MEPicides: α,β-unsaturated Fosmidomycin N-Acyl Analogs as Efficient Inhibitors of Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate reductoisomerase. [PDF]

ACS Infect Dis, 2023
Wang X, Edwards RL, Ball HS, Heidel KM, Brothers RC, Johnson C, Haymond A, Girma M, Dailey A, Roma JS, Boshoff HI, Osbourn DM, Meyers MJ, Couch RD, Odom John AR, Dowd CS.   +15 more
europepmc   +1 more source

The Fsr transporter of <i>Sinorhizobium meliloti</i> contributes to antimicrobial resistance and symbiosis with alfalfa. [PDF]

Microbiology (Reading)
Chávez-Jacobo VM, Reyes-González AR, Girard L, Dunn MF.   +3 more
europepmc   +1 more source

Expression of toxic genes in Methylorubrum extorquens with a tightly repressed, cumate-inducible promoter. [PDF]

Antonie Van Leeuwenhoek, 2023
Pöschel L, Gehr E, Jordan P, Sonntag F, Buchhaupt M.   +4 more
europepmc   +1 more source

Stable Isotopic Labeling of Dimethylallyl Pyrophosphate (DMAPP) Reveals Compartmentalization of Isoprenoid Biosynthesis during Sporulation in <i>Bacillus subtilis</i>. [PDF]

J Am Chem Soc
McBee DP, Hulsey ZN, Hedges MR, Baccile JA.   +3 more
europepmc   +1 more source

The Multifaceted MEP Pathway: Towards New Therapeutic Perspectives. [PDF]

Molecules, 2023
Allamand A, Piechowiak T, Lièvremont D, Rohmer M, Grosdemange-Billiard C.   +4 more
europepmc   +1 more source

Structural diversity of isoprene synthases in mosses from multiple terpenoid synthase lineages. [PDF]

J Biol Chem
Kawakami T, Miyazaki S, Inoue Y, Kawaide H.   +3 more
europepmc   +1 more source