Results 31 to 40 of about 13,321 (212)
Advances in the study of core fucosylation in mammals
浙江大学学报. 农业与生命科学版, 2021 Glycosylation is a major posttranslational modification, which involves in the regulation of important physiological functions. Among them, core fucosylation is an α1, 6-linked fucose to N-glycans, which catalyzes by only one glycosyltransferase.
TIAN Yinping, YI Wen
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Semisynthetic Isomers of Fucosylated Chondroitin Sulfate Polysaccharides with Fucosyl Branches at a Non-Natural Site [PDF]
Biomacromolecules, 2021 The several interesting activities detected for fucosylated chondroitin sulfate (fCS) have fueled in the last years several efforts toward the obtainment of fCS oligosaccharides and low molecular weight (LMW) polysaccharides with a well-defined structure, in order to avoid the problems associated with the potential employment of native, sea cucumber ...
Vessella, Giulia +7 more
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Core fucosylation and its roles in gastrointestinal glycoimmunology
World Journal of Gastrointestinal Oncology, 2023 Glycosylation is a common post-translational modification in eukaryotic cells. It is involved in the production of many biologically active glycoproteins and the regulation of protein structure and function.
Nian-Zhu Zhang +7 more
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Fucosylated glycoproteins and fucosylated glycolipids play opposing roles in cholera intoxication
, 2023 SUMMARY Cholera toxin (CT) is the etiological agent of cholera. Here we report that multiple classes of fucosylated glycoconjugates function in CT binding and intoxication of intestinal epithelial cells. In Colo205 cells, knockout of B3GNT5, the enzyme required for synthesis of lacto- and neolacto-series glycosphingolipids (GSLs ...
Atossa C. Ghorashi +9 more
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Fucosylation and gastrointestinal cancer
World Journal of Hepatology, 2010 Fucose (6-deoxy-L-galactose) is a monosaccharide that is found on glycoproteins and glycolipids in verte-brates, invertebrates, plants, and bacteria. Fucosylation, which comprises the transfer of a fucose residue to oligosaccharides and proteins, is regulated by many kinds of molecules, including fucosyltransferases, GDP-fucose synthetic enzymes, and ...
Kenta, Moriwaki, Eiji, Miyoshi
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International Journal of Molecular Sciences, 2023 Epithelial cells can undergo apoptosis by manipulating the balance between pro-survival and apoptotic signals. In this work, we show that TRAIL-induced apoptosis can be differentially regulated by the expression of α(1,6)fucosyltransferase (FucT-8), the ...
Rubén López-Cortés +4 more
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Cell Host and Microbe, 2022 Summary Interactions between the enteric nervous system (ENS) and intestinal epithelium are thought to play a vital role in intestinal homeostasis. How the ENS monitors the frontier with commensal and pathogenic microbes while maintaining epithelium ...
Chao Lei +6 more
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Frontiers in Chemistry, 2020 Changes in the abundance of antennary fucosylated glycans in human total plasma N-glycome (TPNG) have been associated with several diseases ranging from diabetes to various forms of cancer. However, it is challenging to address this important part of the
Osmond D. Rebello +10 more
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Antibody fucosylation predicts disease severity in secondary dengue infection
Science, 2021 IgG fucosylation predicts dengue severity Secondary infections with dengue virus (DENV) can produce life-threatening symptoms, including thrombocytopenia and hemorrhagic disease, when preexisting DENV-reactive immunoglobulin G1 (IgG1) antibodies promote ...
S. Bournazos +8 more
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Frontiers in Physiology, 2017 Cancer pain is a common and severe complication of human breast cancer, and relieving pain is fundamental strategy in the treatment. Fentanyl, as an opioid analgesic, is widely used in breast cancer patients. However, little is known about its effects on
Hong-Fang Yang +7 more
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