Results 51 to 60 of about 9,249 (168)

Analysis of Xyloglucan Fucosylation in Arabidopsis

Plant Physiology, 2003
AbstractXyloglucan (XyG) is a load-bearing primary wall component in dicotyledonous and non-graminaceous monocotyledonous plants. XyG fucosyltransferase (FUTase), encoded by the Arabidopsis gene AtFUT1, directs addition of fucose (Fuc) residues to terminal galactose residues on XyG side chains.
Robyn M, Perrin, Zhonghua, Jia, Tanya A, Wagner, Malcolm A, O'Neill, Rodrigo, Sarria, William S, York, Natasha V, Raikhel, Kenneth, Keegstra   +7 more
openaire   +3 more sources

Fucosylated Glycoproteins as Markers of Liver Disease [PDF]

Disease Markers, 2008
Changes in N‐linked glycosylation are known to occur during the development of various diseases. For example, increased branching of oligosaccharides has been associated with cancer metastasis and has been correlated to tumor progression in human cancers of the breast, colon and melanomas.
Mehta, Anand, Block, Timothy M.
openaire   +2 more sources

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

Advanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou, Xu Chen, Nina Li, Meiyan Zou, Yunfan Lin, Pei Lin, Weiyao Feng, Xinyuan Zhao, Li Cui   +8 more
wiley   +1 more source

Fucosylation Promotes Cytolytic Function and Accumulation of NK Cells in B Cell Lymphoma

Frontiers in Immunology, 2022
Natural killer (NK) cells have been demonstrated as a promising cellular therapy as they exert potent anti-tumor immune responses. However, applications of NK cells to tumor immunotherapy, especially in the treatment of advanced hematopoietic and solid ...
Xing Tong, Xing Tong, Xing Tong, Xing Tong, Yuhua Ru, Yuhua Ru, Yuhua Ru, Jianhong Fu, Jianhong Fu, Jianhong Fu, Ying Wang, Ying Wang, Ying Wang, Jinjin Zhu, Jinjin Zhu, Jinjin Zhu, Yiyang Ding, Yiyang Ding, Yiyang Ding, Fulian Lv, Fulian Lv, Fulian Lv, Menglu Yang, Menglu Yang, Menglu Yang, Xiya Wei, Xiya Wei, Xiya Wei, Chenchen Liu, Chenchen Liu, Chenchen Liu, Xin Liu, Xin Liu, Xin Liu, Lei Lei, Lei Lei, Lei Lei, Xiaojin Wu, Xiaojin Wu, Xiaojin Wu, Lingchuan Guo, Yang Xu, Yang Xu, Yang Xu, Jie Li, Peng Wu, Huanle Gong, Huanle Gong, Huanle Gong, Jia Chen, Jia Chen, Jia Chen, Depei Wu, Depei Wu, Depei Wu   +54 more
doaj   +1 more source

CSF‐Compartmentalized Antibody Glycoprofiles in NMDAR Encephalitis Associate with Etiology and Functional Recovery

Annals of Neurology, EarlyView.
Objective To characterize Fc‐glycosylation profiles in patients with anti‐N‐methyl‐D‐aspartate receptor encephalitis (NMDARe) and assess their association with antibody compartmentalization (cerebrospinal fluid [CSF] vs serum), disease triggers (viral, tumor‐related or idiopathic), and 1‐year outcomes.
Laura Marmolejo, Claudia Papi, Chiara Milano, Esther Aguilar, Estibaliz Maudes, Ivana Duvnjak Orešković, Jerko Štambuk, Maja Pučić‐Baković, Gemma Olivé‐Cirera, Elianet Fonseca, Mar Guasp, Eugenia Martinez‐Hernandez, Helena Ariño, Takahiro Iizuka, Thais Armangué, Josep Dalmau, Marianna Spatola   +16 more
wiley   +1 more source

Core fucosylation regulates the ovarian response via FSH receptor during follicular development

Journal of Advanced Research
Introduction: Ovarian low response to follicle-stimulating hormone (FSH) causes infertility featuring hypergonadotropic hypogonadism, ovarian failure, and/or defective ovarian response.
Tiantong Wang, Zhiwei Zhang, Changduo Qu, Wanli Song, Ming Li, Xiaoguang Shao, Tomohiko Fukuda, Jianguo Gu, Naoyuki Taniguchi, Wenzhe Li   +9 more
doaj   +1 more source

O-Fucosylation Is Required for ADAMTS13 Secretion [PDF]

Journal of Biological Chemistry, 2007
ADAMTS13 is a plasma metalloproteinase that cleaves von Willebrand factor to smaller, less thrombogenic forms. Deficiency of ADAMTS13 activity in plasma leads to thrombotic thrombocytopenic purpura. ADAMTS13 contains eight thrombospondin type 1 repeats (TSR), seven of which contain a consensus sequence for the direct addition of fucose to the hydroxyl ...
Lindsay M, Ricketts, Malgosia, Dlugosz, Kelvin B, Luther, Robert S, Haltiwanger, Elaine M, Majerus   +4 more
openaire   +2 more sources

Milk: Nature's Unique Nutritional Package

Animal Research and One Health, EarlyView.
ABSTRACT Plant‐based beverages that attempt to mimic milk are increasingly popular with consumers, but there are profound differences in nutritional composition and microstructure compared to milk. A structural nutrition approach is needed to understand the effect on digestibility of microstructures, bioaccessibility and bioavailability of components ...
David W. Everett, Caroline Thum
wiley   +1 more source

Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation

Scientific Reports, 2017
Glycosylation of uterine endometrial cells plays important roles to determine their receptive function to blastocysts. Trophoblast-derived pregnancy-associated plasma protein A (PAPPA) is specifically elevated in pregnant women serum, and is known to ...
Ming Yu, Jiao Wang, Shuai Liu, Xiaoqi Wang, Qiu Yan   +4 more
doaj   +1 more source

Expanding the Toolbox for Inducible Protein Expression With Automation‐enabled Generation of Glycomimetics

Chemistry – A European Journal, EarlyView.
Inducible protein expression is a cornerstone of many aspects of industrial and molecular biotechnological processes. 2′‐fucosyl isopropyl‐β‐D‐thiogalactopyranose (2′F‐IPTG) and 2′‐fucosyl isobutyl‐C‐galactoside (2′F‐IBCG) mimics were explored for protein expression studies.
Ashley E. DeYong, Keevan C. Marion, Murat Ozturk, Sanjeeva Kumar Murali, Fatima Enam, Thomas J. Mansell, Nicola L. B. Pohl   +6 more
wiley   +1 more source