Results 61 to 70 of about 17,469 (199)

Diagnostic accuracy of urinary prostate protein glycosylation profiling in prostatitis diagnosis [PDF]

open access: yes, 2015
Introduction: Although prostatitis is a common male urinary tract infection, clinical diagnosis of prostatitis is difficult. The developmental mechanism of prostatitis is not yet unraveled which led to the elaboration of various biomarkers. As changes in
Decaestecker, Karel   +8 more
core   +2 more sources

Dynamic pH profiles drive higher cell‐specific and volumetric productivity

open access: yesBiotechnology Progress, EarlyView.
Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert   +6 more
wiley   +1 more source

Glycans and glycosaminoglycans in neurobiology: key regulators of neuronal cell function and fate [PDF]

open access: yes, 2018
The aim of the present study was to examine the roles of l-fucose and the glycosaminoglycans (GAGs) keratan sulfate (KS) and chondroitin sulfate/dermatan sulfate (CS/DS) with selected functional molecules in neural tissues.
Hayes, Anthony J., Melrose, James
core   +2 more sources

Novel function of pregnancy-associated plasma protein A: promotes endometrium receptivity by up-regulating N-fucosylation

open access: yesScientific Reports, 2017
Glycosylation of uterine endometrial cells plays important roles to determine their receptive function to blastocysts. Trophoblast-derived pregnancy-associated plasma protein A (PAPPA) is specifically elevated in pregnant women serum, and is known to ...
Ming Yu   +4 more
doaj   +1 more source

Blocking core fucosylation of epidermal growth factor (EGF) receptor prevents peritoneal fibrosis progression [PDF]

open access: gold, 2021
Changqing Yu   +6 more
openalex   +1 more source

Expanding the Toolbox for Inducible Protein Expression With Automation‐enabled Generation of Glycomimetics

open access: yesChemistry – A European Journal, EarlyView.
Inducible protein expression is a cornerstone of many aspects of industrial and molecular biotechnological processes. 2′‐fucosyl isopropyl‐β‐D‐thiogalactopyranose (2′F‐IPTG) and 2′‐fucosyl isobutyl‐C‐galactoside (2′F‐IBCG) mimics were explored for protein expression studies.
Ashley E. DeYong   +6 more
wiley   +1 more source

Mucin glycosylation and sulphation in airway epithelial cells is not influenced by cystic fibrosis transmembrane conductance regulator expression [PDF]

open access: yes, 2005
Abnormalities in mucus properties and clearance make a major contribution to the pathology of cystic fibrosis (CF). Our aim was to test the hypothesis that the defects in CF mucus are a direct result of mutations in the CF transmembrane conductance ...
Dell, Anne   +6 more
core   +1 more source

Core fucosylation regulates the ovarian response via FSH receptor during follicular development

open access: yesJournal of Advanced Research
Introduction: Ovarian low response to follicle-stimulating hormone (FSH) causes infertility featuring hypergonadotropic hypogonadism, ovarian failure, and/or defective ovarian response.
Tiantong Wang   +9 more
doaj   +1 more source

A spoonful of L‐fucose—an efficient therapy for GFUS‐CDG, a new glycosylation disorder

open access: yesEMBO Molecular Medicine, 2021
Congenital disorders of glycosylation are a genetically and phenotypically heterogeneous family of diseases affecting the co‐ and posttranslational modification of proteins.
René G Feichtinger   +10 more
doaj   +1 more source

Abnormal B cell glycosylation in autoimmunity: A new potential treatment strategy

open access: yesFrontiers in Immunology, 2022
Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are two autoimmune diseases characterised by the production of pathogenic autoreactive antibodies. Their aetiology is poorly understood. Nevertheless, they have been shown to involve
Marie Morel   +18 more
doaj   +1 more source

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