Results 91 to 100 of about 11,885 (204)

Biomimetic synthesis of galantamine via laccase/TEMPO mediated oxidative coupling

, 2020
Laccase-mediated intramolecular oxidative radical coupling of N-formyl-2-bromo-O-methylnorbelladine afforded a novel and isolable spirocyclohexadienonic intermediate of galantamine.
Claudio Zippilli, Maria Camilla Baratto, Saladino, Raffaele, Baratto, Maria Camilla, Botta, Lorenzo, Pogni, Rebecca, Lorenzo Botta, Bizzarri, Bruno Mattia, Zippilli, Claudio, Raffaele Saladino, Rebecca Pogni, Bruno Mattia Bizzarri   +11 more
core   +1 more source

Galantamine demonstrates efficacy and safety in elderly patients with Alzheimer disease

, 2003
Alzheimer disease (AD) treatment guidelines state that cholinergic agents are not cost-effective in patients with more severe disease. Because many physicians may deem an older patient unlikely to respond to treatment, older AD patients may remain ...
Bullock, Roger, Schwalen, Susanne, Gauthier, Serge, Marcusson, Jan,, Kurz, Alexander   +4 more
core   +1 more source

Clinically meaningful treatment responses after switching to galantamine and with addition of memantine in patients with Alzheimer’s disease receiving donepezil

Neuropsychiatric Disease and Treatment, 2013
Osamu Kano,1 Hirono Ito,1 Takanori Takazawa,1 Yuji Kawase,1 Kiyoko Murata,1 Konosuke Iwamoto,1 Tetsuro Nagaoka,1 Takehisa Hirayama,1 Ken Miura,1 Riya Nagata,1 Tetsuhito Kiyozuka,2 Jo Aoyagi,2 Ryuta Sato,2 Teruo Eguchi,3 Ken Ikeda,1 Yasuo ...
Kano O, Ito H, Takazawa T, Kawase Y, Murata K, Iwamoto K, Nagaoka T, Hirayama T, Miura K, Nagata R, Kiyozuka T, Aoyagi J, Sato R, Eguchi T, Ikeda K, Iwasaki Y   +15 more
doaj  

Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Molecules, 2017
The actions of many drugs involve enzyme inhibition. This is exemplified by the inhibitors of monoamine oxidases (MAO) and the cholinsterases (ChE) that have been used for several pharmacological purposes.
Rona R. Ramsay, Keith F. Tipton
doaj   +1 more source

Efficacy and safety of galantamine in patients with mild to moderate Alzheimer's disease: multicentre randomised controlled trial. Galantamine International-1 Study Group.

, 2000
OBJECTIVE: To evaluate the efficacy and safety of galantamine in the treatment of Alzheimer's disease. DESIGN: Randomised, double blind, parallel group, placebo controlled trial. SETTING: 86 outpatient clinics in Europe and Canada.
Wilcock, GK, Lilienfeld, S, Wilcock, Gordon, Gaens, E   +3 more
core   +1 more source

Galantamine protects against hydrochloric acid aspirationinduced acute respiratory distress syndrome in rabbits

, 2018
Purpose: To study the effect of galantamine on anti-inflammatory responses in acid aspiration-induced acute respiratory syndrome (ARDS), and the underlying mechanism.Methods: Six groups of male rabbits (156), i.e., control group, ARDS group, galantamine +
Peng, Yan, Yang, Jin, Yang, Yi
core   +1 more source

Applications of snowdrop medicinal plant material in homeopathic pharmacy: a brief historical background and a systematic review of homeopathic medicines standardization

Сеченовский вестник, 2015
Currently, relevant studies are related to the development of private pharmacopeia articles with the requirements for medicinal plant raw materials and homeopathic mother tincture used in homeopathic practice. The article presents a brief overview of the
D. O. Bokov, I. A. Samylina
doaj  

Effect of galantamine on platelet functions in healthy elderly people

, 2013
Background & objectives: Galantamine, a centrally-acting cholinesterase inhibitor, has been used in the treatment of mild-to-moderate dementia of Alzheimer disease.
Celik, Turgay, Bozoglu, Ergun, IŞIK, AHMET TURAN, Kaptan, Kursat   +3 more
core  

GALANTAMINE CONTENT IN LEUCOJUM AESTIVUM POPULATIONS GROWN IN NORTHWEST ALBANIA

, 2016
Although chemical synthesis of galantamine is feasible, plants are still the main sources of production for this natural product. Galantamine, a reversible acethylcholinesterase inhibitor, has been used for decades for various medicinal purposes.
Klosi, Rilinda; GRIAS Research Centre, Gavani, Eva; National Agency of Drugs and Medical Devices, Tirana, Mersinllari, Mersin; Faculty of Natural Sciences, Tirana University   +2 more
core  

Galantamine postischemia provides neuroprotection and memory recovery against transient global cerebral ischemia in gerbils

, 2007
Galantamine, currently used in Alzheimer's patients, has shown neuroprotection in hippocampal slices subjected to oxygenglucose deprivation. Here, we present an in vivo study to evaluate the potential neuroprotective effects of galantamine in a transient
Roda, José M, Arias, Esperanza, García, Antonio G, López, Manuela G, Sobrado, Mónica, Lorrio, Silvia   +5 more
core   +1 more source