Results 81 to 90 of about 18,542 (210)

Transcriptome Analysis and Metabolic Profiling of Lycoris Radiata

open access: yesBiology, 2019
Lycoris radiata belongs to the Amaryllidaceae family and is a bulbous plant native to South Korea, China, and Japan. Galantamine, a representative alkaloid of Amaryllidaceae plants, including L.
Chang Ha Park   +5 more
doaj   +1 more source

Integrated Network Pharmacology, Molecular Docking, and Experimental Validation Elucidating the Therapeutic Mechanism of Idesia polycarpa Crude Oil in Aluminum Chloride‐Induced Alzheimer's Rat Models

open access: yesFood Science &Nutrition, Volume 14, Issue 4, April 2026.
Step 1: Component identification and target screening: The chemical composition of IPCO was characterized using GC–MS, identifying two major fatty acids and six fat‐soluble active substances. A total of 149 potential drug targets were predicted via Pharm Mapper and SwissTargetPrediction. Concurrently, 2029 genes associated with Alzheimer's Disease (AD)
Weijie Chang   +4 more
wiley   +1 more source

Biogenic Synthesis of ZnO Nanoparticles From Heliotropium europaeum and Assessment of Antibiofilm, Anti‐Quorum‐Sensing, Antioxidant and Anticholinesterase Activities

open access: yesNatural Sciences, Volume 6, Issue 2, April 2026.
Synthesis, characterization and biological activities of ZnO nanoparticles. ABSTRACT Zinc oxide nanoparticles (ZnO‐NPs) are inexpensive, non‐toxic, and biocompatible with human cells, making them suitable for biomedical applications. In the present study, ZnO‐NPs were synthesized from Heliotropium europaeum extracts at different concentrations through ...
Adel Manseur   +8 more
wiley   +1 more source

The Effects of an Uninterrupted Switch from Donepezil to Galantamine without Dose Titration on Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2014
Aims: To elucidate the efficacy of galantamine on cognition and behavioral and psychological symptoms of dementia (BPSD) in outpatients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) who have switched from donepezil to galantamine ...
Shoichi Sasaki, Yoshiharu Horie
doaj   +1 more source

Contribución de los receptores nicotícos a la neuroprotección y a la neuroinflamación [PDF]

open access: yes, 2014
Tesis doctoral inédita leída en la Universidad Autónoma de Madrid. Facultad de Medicina. Departamento de Farmacología y Terapéutica.
Parada Pérez, Esther
core   +1 more source

CSF Cholinergic Index, a New Biomeasure of Treatment Effect in Patients With Alzheimer’s Disease

open access: yesFrontiers in Molecular Neuroscience, 2019
Alzheimer’s disease (AD) is a progressive disease with early degeneration of the central cholinergic neurons. Currently, three of four AD drugs act by inhibiting the acetylcholine (ACh) degrading enzyme, acetylcholinesterase (AChE).
Azadeh Karami   +8 more
doaj   +1 more source

Dynamic mechanical properties of oral mucosa: comparison with polymeric soft denture liners. [PDF]

open access: yes, 2011
The purpose of this work was to characterize the viscoelastic behaviour of oral mucosa and compare it with the dynamic mechanical properties of different soft liners. For this purpose, a sample of pig oral mucosa and six commercialized soft liner samples
Dandurand, Jany   +5 more
core   +2 more sources

Synergistic Effects of Galantamine and Memantine in Attenuating Scopolamine-Induced Amnesia in Mice

open access: yesJournal of Pharmacological Sciences, 2012
We investigated a possible drug efficacy enhancement obtained by combining inactive doses of galantamine and memantine in the scopolamine-induced amnesia model in mice.
Perrine Busquet   +5 more
doaj   +1 more source

Perifériás markerek jelentősége Alzheimer-kór diagnózisában és terápiájában = Peripheral markers in the diagnosis and the therapy of Alzheimer`s disease [PDF]

open access: yes, 2006
A legjelentősebb neurokémiai abnormalitás az Alzheimer-kórban (AK) a központi idegrendszer kolinerg rendszerének csökkent működése, de feltehetőleg a perifériás szövetek is érintettek lehetnek.
Kálmán, János, Rakonczay, Zoltán
core  

Acetylcholinesterase Inhibitor Ameliorates Early Cardiometabolic Disorders in Fructose-Overloaded Rat Offspring

open access: yesPharmaceuticals
Background: We investigate the role of galantamine on autonomic dysfunction associated with early cardiometabolic dysfunction in the offspring of fructose-overloaded rats.
Victor Hugo Martins de Miranda   +7 more
doaj   +1 more source

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