Results 101 to 110 of about 18,363 (193)

Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Molecules, 2017
The actions of many drugs involve enzyme inhibition. This is exemplified by the inhibitors of monoamine oxidases (MAO) and the cholinsterases (ChE) that have been used for several pharmacological purposes.
Rona R. Ramsay, Keith F. Tipton
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Applications of snowdrop medicinal plant material in homeopathic pharmacy: a brief historical background and a systematic review of homeopathic medicines standardization

Сеченовский вестник, 2015
Currently, relevant studies are related to the development of private pharmacopeia articles with the requirements for medicinal plant raw materials and homeopathic mother tincture used in homeopathic practice. The article presents a brief overview of the
D. O. Bokov, I. A. Samylina
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THE DRAMATIC EFFECTS OF GALANTAMINE IN A PATIENT WITH EARLY-ONSET ALZHEIMER’S DISEASE [PDF]

, 2010
Introduction: We discuss the case of a 51 year old former mid-wife presented to the NHS Luton and Bedfordshire psychiatric services with a 2 year history of increasing forgetfulness with significant impairment to her daily function.
Harveer Dev, Mark Agius, Rashid Zaman
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Representation learning of drug and disease terms for drug repositioning

, 2017
Drug repositioning (DR) refers to identification of novel indications for the approved drugs. The requirement of huge investment of time as well as money and risk of failure in clinical trials have led to surge in interest in drug repositioning.
Anand, Ashish, Manchanda, Sahil
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Using practice effects for targeted trials or sub-group analysis in Alzheimer\u27s disease: How practice effects predict change over time [PDF]

, 2020
OBJECTIVE: To describe the presence of practice effects in persons with Alzheimer disease (AD) or mild cognitive impairment (MCI) and to evaluate how practice effects affect cognitive progression and the outcome of clinical trials.
Cutter, Gary R, Fowler, Mackenzie E, Goldberg, Terry E, Kennedy, Richard E, Schneider, Lon S, Wang, Guoqiao   +5 more
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Clinically meaningful treatment responses after switching to galantamine and with addition of memantine in patients with Alzheimer’s disease receiving donepezil

Neuropsychiatric Disease and Treatment, 2013
Osamu Kano,1 Hirono Ito,1 Takanori Takazawa,1 Yuji Kawase,1 Kiyoko Murata,1 Konosuke Iwamoto,1 Tetsuro Nagaoka,1 Takehisa Hirayama,1 Ken Miura,1 Riya Nagata,1 Tetsuhito Kiyozuka,2 Jo Aoyagi,2 Ryuta Sato,2 Teruo Eguchi,3 Ken Ikeda,1 Yasuo ...
Kano O, Ito H, Takazawa T, Kawase Y, Murata K, Iwamoto K, Nagaoka T, Hirayama T, Miura K, Nagata R, Kiyozuka T, Aoyagi J, Sato R, Eguchi T, Ikeda K, Iwasaki Y   +15 more
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NMR Metabolomic Profiling of Differentiated SH-SY5Y Neuronal Cells: Amyloid-β Toxicity and Protective Effects of Galantamine and Lycorine

Cells
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder characterized by metabolic dysregulation, oxidative stress, amyloid-β (Aβ) aggregation, metal dyshomeostasis, and mitochondrial dysfunction.
Arian Kola, Filippo Costanti, Jordan Kahfi, Abdul-Hamid Emwas, Mariusz Jaremko, Daniela Valensin   +5 more
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Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer’s disease: A systematic review and meta-analysis

Clinical Interventions in Aging, 2008
Richard A Hansen1, Gerald Gartlehner2, Aaron P Webb1, Laura C Morgan3, Charity G Moore4, Daniel E Jonas31School of Pharmacy, 3Cecil G Sheps Center for Health Services Research, University of North Carolina, Chapel Hill, NC, USA; 2Department for Evidence ...
Richard A Hansen, Gerald Gartlehner, Aaron P Webb, Laura C Morgan, Charity G Moore, Daniel E Jonas   +5 more
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Comparison of two pharmaceutical production processes using different eco-efficiency measuring methods [PDF]

, 2011
Aelterman, Wim, Dewulf, Jo, Schaerlaekens, Kristien, Stouthuyzen, Peter, Van Broeck, Peter, Van der Vorst, Geert, Van Langenhove, Herman, Walraedt, Saskia   +7 more
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Long-term effect of galantamine on cognitive function in patients with Alzheimer’s disease versus a simulated disease trajectory: an observational study in the clinical setting

Neuropsychiatric Disease and Treatment, 2017
Ryoko Nakagawa,1 Takashi Ohnishi,1 Hisanori Kobayashi,1 Toshio Yamaoka,2 Tsutomu Yajima,3 Ai Tanimura,4 Toshiya Kato,4 Kazutake Yoshizawa1 1Evidence Generation Department, Medical Affairs Division, 2Clinical Data Management Department, R&D Division,
Nakagawa R, Ohnishi T, Kobayashi H, Yamaoka T, Yajima T, Tanimura A, Kato T, Yoshizawa K   +7 more
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