Results 41 to 50 of about 18,363 (193)
The kynurenine pathway and the brain: challenges, controversies and promises [PDF]
, 2017 Research on the neurobiology of the kynurenine pathway has suffered years of relative obscurity because tryptophan degradation, and its involvement in both physiology and major brain diseases, was viewed almost exclusively through the lens of the well ...
Schwarcz, Robert, Stone, Trevor W.
core +1 more source
Portals to Wonderland: Health portals lead to confusing information about the effects of health care [PDF]
, 2005 Background The Internet offers a seemingly endless amount of health information of varying quality. Health portals, which provide entry points to quality-controlled collections of websites, have been hailed as a solution to this problem. The objective of
Claire Glenton +2 more
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Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2021 Introduction Cholinesterase inhibitors can enhance cognitive functions in healthy elderly and delay cognitive decline in patients with Alzheimer`s disease (AD). However, not everyone benefits from this treatment (non‐responders).
Patrick Müller +6 more
doaj +1 more source
Anti-Cholinesterase Combination Drug Therapy as a Potential Treatment for Alzheimer’s Disease
Brain Sciences, 2021 Alzheimer’s disease (AD) is a burgeoning social and healthcare problem. Cholinesterase inhibitors (ChEIs) are employed for symptomatic treatment of AD, but often elicit adverse drug reactions (ADRs).
Hafsa Amat-ur-Rasool +3 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
Thiol-reactive analogues of galanthamine, codeine and morphine as potential probes to interrogate allosteric binding within nAChRs [PDF]
, 2016 Alkaloids including galanthamine (1) and codeine (2) are reported to be positive allosteric modulators of nicotinic acetylcholine receptors (nAChRs) but the binding sites responsible for this activity are not known with certainty.
Balle, Thomas +3 more
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ELECTROPHORESIS, EarlyView.ABSTRACT This study describes the use of microchip micellar electrokinetic chromatography (MEKC) integrated with capacitively coupled contactless conductivity detection (C4D) for the determination of monoethylene glycol (MEG) in gas condensate samples.
Maurício M. L. Pereira +6 more
wiley +1 more source
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Background Schizophrenia is characterized by positive, negative, and cognitive symptoms. Current pharmacological treatments often fail to address cognitive deficits. In this review of clinical trials, we aim to identify studies that explore neurobiological (non‐psychological) strategies to address Cognitive Impairment Associated with ...
Bahareh Peyrovian +3 more
wiley +1 more source
The influence of in vitro gastrointestinal digestion on the chemical composition and antioxidant and enzyme inhibitory capacities of carob liqueurs obtained with different elaboration techniques [PDF]
, 2019 Carob liqueur is a traditional Mediterranean alcoholic beverage obtained via a wide range of production techniques contributing to the different organoleptic attributes of the final product.
Coelho, Natacha +5 more
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Turkish Journal of Agriculture: Food Science and Technology, 2019 The aim of this study was to determine the effect of different doses and combinations of benzylaminopurine (BAP) and Putrescine elicitor on some plant characteristics of summer snowflake (Leucojum aestivum L.).
Mehmet Uğur Yıldırım +5 more
doaj +1 more source