Results 171 to 180 of about 20,091 (201)
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Microbial transformations of galanthamin-precursors
Applied Microbiology and Biotechnology, 1986Galanthamin is a medical important alkaloid. Its chemical synthesis gives a racemic product in low yields. Starting with a belladinderivative an enzymatic ring closure should lead exclusively to a chiral product possibly with the native structure. Although this reactions type is unknown in preparative biotransformations a large number of microorganisms
G. Spassov +7 more
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Total Synthesis of (.+‐.)‐Galanthamine (I).
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Xiang‐Dong Hu +7 more
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Facile synthesis of (±)‐, (+)‐, and (‐)‐galanthamine
Journal of Heterocyclic Chemistry, 1995AbstractThe Amarylidacea alkaloid galanthamine (1a) is an acetylcholinesterase inhibitor that has been evaluated as a potential agent for the treatment of Alzheimer's disease. We report a very efficent synthesis of (±)‐galanthamine [(±)‐1a] from readily available isovanillin and tyramine.
Jerzy Szewczyk +3 more
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Galanthamine in Alzheimer’s Disease
1994Substantial efforts have been made in neurobiology and molecular biology but we are still far from a causal therapy of Alzheimer’s disease (AD). In the interim, and perhaps ultimately as an adjunct to a progression inhibitor which may not be absolute, symptomatic treatment has to be optimized. Tacrine’s approval by the FDA has stimulated a search for a
Helmut Kewitz +2 more
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Daffodil production for galanthamine
Galanthamine is a bioactive that has proven effect to reduce the effect of Alzheimer's. A source of natural galanthamine is from daffodils, but only certain varieties grown under specific conditions produce enough galanthamine to make it economically viable to extract for commercial purposes.Pyke, Nick +4 more
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Galanthamine hydrobromide in mania
The Lancet, 1991Ernir Snorrason, JónG. Stefánsson
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