The Occurrence and Bioactivities of <i>Amaryllidaceae</i> Alkaloids from Plants: A Taxonomy-Guided Genera-Wide Review. [PDF]
Plants (Basel)The distribution of Amaryllidaceae alkaloids, with a focus on their chemodiversity, has been reported previously, but not at a genera-wide diversity level.
Lin GD, Vishwakarma P, Smith PN, Li RW.
europepmc +2 more sources
Tissue-Specific Natural Synthesis of Galanthaminein Zephyranthes Species and Its Accumulation in Different In Vitro-Grown Organs Following Methyl Jasmonate Treatment. [PDF]
Plants (Basel)Galanthamine is an immensely valuable alkaloid exhibiting anti-cancer and antiviral activity. The cultivation of plant tissues in in vitro conditions is a good source for the synthesis and enrichment of secondary metabolites of commercial interest.
Syeed R +9 more
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Frontiers in Chemistry, 2023 As global ageing deepens and galanthamine is the preferred clinical drug for the treatment of mild to moderate Alzheimer’s disease, it will be valuable to examine the behaviour and mechanism of galanthamine’s thermal decomposition for its quality control,
Chong Qin +3 more
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Integrating Narcissus-derived galanthamine production into traditional upland farming systems
Scientific Reports, 2021 Alzheimer’s disease (AD) is a disorder associated with progressive degeneration of memory and cognitive function. Galantamine is a licenced treatment for AD but supplies of the plant alkaloid that it is produced from, galanthamine, are limited.
M. D. Fraser +4 more
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Chemical Survey of Three Species of the Genus Rauhia Traub (Amaryllidaceae)
Plants, 2022 Plant biodiversity is an important source of compounds with medicinal properties. The alkaloid galanthamine, first isolated from Galanthus woronowii (Amaryllidaceae), is approved by the FDA for the palliative treatment of mild to moderate Alzheimer’s ...
Luciana R. Tallini +7 more
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Unlocking the Antioxidant, Enzyme Inhibitory and Acaricidal Potential of <i>Azadirachta indica</i> Phytoconstituents Using In Vitro and In Silico Approaches. [PDF]
Food Sci NutrThe study evaluated the acaricidal potential of bioactive components of Azadirachta indica against scabies mortality using both in vitro and in silico methodologies. Sarcoptes scabiei were stimulated with Azadirachta indica at four concentrations (25–100 mg/mL) at different intervals.
Fatima T +8 more
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Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus. [PDF]
PLoS ONE, 2014 Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer's disease. This compound is primarily isolated from daffodil (Narcissus spp.), snowdrop (Galanthus spp.), and summer snowflake (Leucojum aestivum).
Matthew B Kilgore +6 more
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Scientific Reports, 2022 Leucojum aestivum is known for its ability to biosynthesize alkaloids with therapeutic properties, among which galanthamine used for the treatment of Alzheimer's disease. New sources of this alkaloid are still being explored.
Agata Ptak +9 more
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Molecules, 2023 Light-emitting diodes (LEDs) have emerged as efficient light sources for promoting in vitro plant growth and primary and secondary metabolite biosynthesis. This study investigated the effects of blue, red, and white-red LED lights on plant biomass growth,
Emilia Morańska +7 more
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Molecules, 2021 The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious agent, killing more than 1.4 million people worldwide each year.
Negar Maafi +14 more
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