Results 11 to 20 of about 20,091 (201)

Conservation Potential Trough In Vitro Regeneration of Two Threatened Medicinal Plants Ungernia sewertzowii and U. victoris [PDF]

Plants
Ungernia sewertzowii (US) and U. victoris (UV) are medicinal plants and sources of biologically active compounds for pharmaceutical needs. The leaves of US contain 0.29–0.81% sum of alkaloids with a predominance of lycorine, which is 0.04–0.46% in leaves
Feruza Usmanovna Mustafina, Hanifabonu Kobul kizi Juraeva, Dilafruz Nematilla kizi Jamalova, Abbos Tulkin ogli Hazratov, Ayimxan Jalgasbaevna Janabaeva, Hoe Jin Kim, Chae Sun Na, Min Sung Lee, Yu Jin Oh, Komiljon Sharobiddinovich Tojibaev, Sodikjon Kholiknazarovich Abdinazarov   +10 more
doaj   +2 more sources

Alkaloid Profile, Anticholinesterase and Antioxidant Activities, and Sexual Propagation in Hieronymiella peruviana (Amaryllidaceae) [PDF]

Plants
Hieronymiella peruviana, a recently described endemic species from southern Peru, belongs to the Amaryllidaceae family and is known for its diversity of alkaloids.
Olimpia Llalla-Cordova, Javier E. Ortiz, Luciana R. Tallini, Laura Torras-Claveria, Jaume Bastida, Lorena Celina Luna, Gabriela E. Feresin   +6 more
doaj   +2 more sources

Analysis on the thermal decomposition kinetics and storage period of biomass-based lycorine galanthamine

Frontiers in Chemistry, 2023
As global ageing deepens and galanthamine is the preferred clinical drug for the treatment of mild to moderate Alzheimer’s disease, it will be valuable to examine the behaviour and mechanism of galanthamine’s thermal decomposition for its quality control,
Chong Qin, Chong Qin, Weihong Ling, Chunlian Tian   +3 more
doaj   +1 more source

Integrating Narcissus-derived galanthamine production into traditional upland farming systems

Scientific Reports, 2021
Alzheimer’s disease (AD) is a disorder associated with progressive degeneration of memory and cognitive function. Galantamine is a licenced treatment for AD but supplies of the plant alkaloid that it is produced from, galanthamine, are limited.
M. D. Fraser, H. E. Vallin, J. R. T. Davies, G. E. Rowlands, X. Chang   +4 more
doaj   +1 more source

Chemical Survey of Three Species of the Genus Rauhia Traub (Amaryllidaceae)

Plants, 2022
Plant biodiversity is an important source of compounds with medicinal properties. The alkaloid galanthamine, first isolated from Galanthus woronowii (Amaryllidaceae), is approved by the FDA for the palliative treatment of mild to moderate Alzheimer’s ...
Luciana R. Tallini, Edison H. Osorio, Strahil Berkov, Laura Torras-Claveria, María L. Rodríguez-Escobar, Francesc Viladomat, Alan W. Meerow, Jaume Bastida   +7 more
doaj   +1 more source

Unlocking the Antioxidant, Enzyme Inhibitory and Acaricidal Potential of <i>Azadirachta indica</i> Phytoconstituents Using In Vitro and In Silico Approaches. [PDF]

Food Sci Nutr
The study evaluated the acaricidal potential of bioactive components of Azadirachta indica against scabies mortality using both in vitro and in silico methodologies. Sarcoptes scabiei were stimulated with Azadirachta indica at four concentrations (25–100 mg/mL) at different intervals.
Fatima T, Abbas M, Zafar K, Zafar MG, Haider W, Zafar MH, Riaz M, Iqbal M, Mtewa AG.   +8 more
europepmc   +2 more sources

Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus. [PDF]

PLoS ONE, 2014
Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer's disease. This compound is primarily isolated from daffodil (Narcissus spp.), snowdrop (Galanthus spp.), and summer snowflake (Leucojum aestivum).
Matthew B Kilgore, Megan M Augustin, Courtney M Starks, Mark O'Neil-Johnson, Gregory D May, John A Crow, Toni M Kutchan   +6 more
doaj   +1 more source

Phenolic Acids and Amaryllidaceae Alkaloids Profiles in Leucojum aestivum L. In Vitro Plants Grown under Different Light Conditions

Molecules, 2023
Light-emitting diodes (LEDs) have emerged as efficient light sources for promoting in vitro plant growth and primary and secondary metabolite biosynthesis. This study investigated the effects of blue, red, and white-red LED lights on plant biomass growth,
Emilia Morańska, Magdalena Simlat, Marzena Warchoł, Edyta Skrzypek, Piotr Waligórski, Dominique Laurain-Mattar, Rosella Spina, Agata Ptak   +7 more
doaj   +1 more source

Endophytic bacteria from in vitro culture of Leucojum aestivum L. a new source of galanthamine and elicitor of alkaloid biosynthesis

Scientific Reports, 2022
Leucojum aestivum is known for its ability to biosynthesize alkaloids with therapeutic properties, among which galanthamine used for the treatment of Alzheimer's disease. New sources of this alkaloid are still being explored.
Agata Ptak, Emilia Morańska, Marzena Warchoł, Artur Gurgul, Edyta Skrzypek, Michał Dziurka, Dominique Laurain-Mattar, Rosella Spina, Anita Jaglarz, Magdalena Simlat   +9 more
doaj   +1 more source

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents

Molecules, 2021
The search for novel antimycobacterial drugs is a matter of urgency, since tuberculosis is still one of the top ten causes of death from a single infectious agent, killing more than 1.4 million people worldwide each year.
Negar Maafi, Abdullah Al Mamun, Ondřej Janďourek, Jana Maříková, Kateřina Breiterová, Adéla Diepoltová, Klára Konečná, Anna Hošťálková, Daniela Hulcová, Jiří Kuneš, Eliška Kohelová, Darja Koutová, Marcela Šafratová, Lucie Nováková, Lucie Cahlíková   +14 more
doaj   +1 more source