Results 61 to 70 of about 20,179 (201)

Recent Advances in Ene Reactions with Carbon Enophiles

Advanced Synthesis &Catalysis, Volume 367, Issue 22, November 28, 2025.
Recent advances in the classical intra‐ and intermolecular ene nexus with carbon enophiles (alkenes, alkynes, arynes, and allenes) show a considerable increase in structural complexity and an enormous potential for functional applications in polymer science.
Thomas J. J. Müller
wiley   +1 more source

Exploring the Multifunctional Agents of Flavonoid‐Rich Beet Leaf Extracts: Insights From Experimental and Computational Studies

Food Safety and Health, Volume 3, Issue 4, Page 723-739, October 2025.
ABSTRACT This study evaluated the multifunctional ability of Beta vulgaris leaves in dual therapy for Alzheimer's disease (AD) and type 2 diabetes (T2D). Flavonoid‐rich extracts of B. vulgaris leaves (FREBVL) were tested for their antidiabetic properties. The inhibition of α‐amylase and α‐glucosidase was assessed. Anti‐cholinesterase activities against
Gideon Ampoma Gyebi, Damilare Emmanuel Rotimi, Moyosoreoluwa Oduba, Ifeoma Nnonyelu, Matthew Iyobhebhe, Musiliyu Ayofe Salawu, Adebola Busola Ojo, Odunayo Anthonia Taiwo, Adesoji Alani Olanrewaju, Abel Kolawole Oyebamiji, Mubarak Alruwaili, Naif H. Ali, Saud A. Alnaaim, Bshra A. Alsfouk, Gaber El‐Saber Batiha, Oluwafemi Adeleke Ojo   +15 more
wiley   +1 more source

Biotechnological Approaches to Optimize the Production of Amaryllidaceae Alkaloids

Biomolecules, 2022
Amaryllidaceae alkaloids (AAs) are plant specialized metabolites with therapeutic properties exclusively produced by the Amaryllidaceae plant family. The two most studied representatives of the family are galanthamine, an acetylcholinesterase inhibitor ...
Manoj Koirala, Vahid Karimzadegan, Nuwan Sameera Liyanage, Natacha Mérindol, Isabel Desgagné-Penix   +4 more
doaj   +1 more source

Deciphering of nutritional profile, therapeutic potential, and networking of bioactive compounds of Moringa oleifera: A comprehensive review

Food Biomacromolecules, Volume 2, Issue 3, Page 271-287, September 2025.
The graphical abstract signifies the nutritional profile of various parts of the Moringa oleifera plant, including dried leaves, fresh leaves, leaf powder, seeds, and pods; along with it’s bioactive substance and protein profiling of aqueous concentrates derived from the fruit, seed, and leaf.
Rajesh Kumar, Sunita Khatak, Vandana, Adarsh Kumar Shukla, Surbhi Panwar, Ashwani Kumar   +5 more
wiley   +1 more source

Antileishmanial Activity of Clinanthus milagroanthus S. Leiva & Meerow (Amaryllidaceae) Collected in Peru

Plants, 2023
Leishmaniasis is a worldwide infectious parasitic disease caused by different species of protozoa of the genus Leishmania, which are transmitted to animals and humans through the bite of insects of the Psychodidae family.
Marilú Roxana Soto-Vásquez, Paul Alan Arkin Alvarado-García, Edison H. Osorio, Luciana R. Tallini, Jaume Bastida   +4 more
doaj   +1 more source

Increased Sensitivity to Agonist-Induced Seizures, Straub Tail, and Hippocampal Theta Rhythm in Knock-In Mice Carrying Hypersensitive α4 Nicotinic Receptors [PDF]

, 2003
We studied a strain of exon replacement mice (“L9′S knock-in”) whose α4 nicotinic receptor subunits have a leucine to serine mutation in the M2 region, 9′ position (Labarca et al., 2001); this mutation renders α4-containing receptors hypersensitive to ...
Collins, Allan C., Damaj, M. Imad, Deshpande, Purnima, Fonck, Carlos, Labarca, Cesar, Lester, Henry A., Marks, Michael J., Nashmi, Raad, Riedel, Anett, Schwarz, Johannes   +9 more
core  

Comprehensive Metabolomic Profiling and Biological Activity Analysis of Eschscholzia californica Extracts Using LC‐ESI‐QTOF‐MS

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
The results indicate the potential pharmacological applications of Eschscholzia californica's aerial parts as a source for the development of novel phytopharmaceuticals targeting conditions such as insomnia, schizophrenia, and depression. ABSTRACT The current investigation was designed to explore the chemical composition, antioxidant capacity, enzyme ...
Alina Kalyniukova, Shakeel Ahmed, Gunes Ak, Enver Saka, Tugce Duran, Nurgul Abul, Ilhami Gulcin, Ismail Senkardes, Mehmet Veysi Cetiz, Gokhan Zengin   +9 more
wiley   +1 more source

Design, synthesis and biological evaluation of 1,3-dihydroxyxanthone derivatives: Effective agents against acetylcholinesterase [PDF]

, 2017
The present work concerns the rational design and development of new inhibitors of acetylcholinesterase (AChE) based on the privileged xanthone scaffold.
Accordino, Sebastian Roberto, Appignanesi, Gustavo Adrian, Biscussi, Brunella, Gerbino, Darío César, Menéndez, Cintia Anabella, Murray, Ana Paula   +5 more
core   +1 more source

Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)

Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.
This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni, Milena Costa Bassicheto, Maria Vitória de Oliveira, Ana Beatriz dos Santos de Souza, Gabriella Melo Alves, Thiago André Moura Veiga   +5 more
wiley   +1 more source

Potential of Naturally Derived Alkaloids as Multi-Targeted Therapeutic Agents for Neurodegenerative Diseases

Molecules, 2021
Alkaloids are a class of secondary metabolites that can be derived from plants, fungi and marine sponges. They are widely known as a continuous source of medicine for the management of chronic disease including cancer, diabetes and neurodegenerative ...
Yew Rong Kong, Kai Ching Tay, Yi Xiang Su, Choon Kwang Wong, Wen Nee Tan, Kooi Yeong Khaw   +5 more
doaj   +1 more source