Learning theories reveal loss of pancreatic electrical connectivity in diabetes as an adaptive response [PDF]
Cells of almost all solid tissues are connected with gap junctions which permit the direct transfer of ions and small molecules, integral to regulating coordinated function in the tissue. The pancreatic islets of Langerhans are responsible for secreting the hormone insulin in response to glucose stimulation.
arxiv +1 more source
Characterization of Asymmetric Gap-Engineered Josephson Junctions and 3D Transmon Qubits [PDF]
We have fabricated and characterized asymmetric gap-engineered junctions and transmon devices. To create Josephson junctions with asymmetric gaps, Ti was used to proximitize and lower the superconducting gap of the Al counter-electrode. DC IV measurements of these small, proximitized Josephson junctions show a reduced gap and larger excess current for ...
arxiv +1 more source
Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments
Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with remodelling of gap junctions and also, although less well-defined, down-regulation of the fast sodium current. The gap junction remodelling and down-regulation of sodium
Ronald eWilders
doaj +1 more source
Connexin’s Connection in Breast Cancer Growth and Progression
Gap junctions are cell-to-cell junctions that are located in the basolateral surface of two adjoining cells. A gap junction channel is composed of a family of proteins called connexins.
Debarshi Banerjee
doaj +1 more source
Structural basis of connexin-36 gap junction channel inhibition. [PDF]
Ding X+10 more
europepmc +2 more sources
Fabrication of Deep-Sub-Micrometer NbN/AlN/NbN Epitaxial Junctions on a Si Substrate [PDF]
We have developed a novel fabrication process for ultra-small, full-epitaxial NbN Josephson junctions on a silicon (Si) substrate. A full-epitaxial NbN/AlN/NbN tri-layer was grown on a Si (100) wafer with a (200)-oriented TiN buffer layer. It was patterned into Josephson junctions by an electron beam lithography (EBL) for junction definition followed ...
arxiv +1 more source
Transport across meso-junctions of highly doped Si with different superconductors [PDF]
We studied the transport properties of meso-junctions of semiconducting (Sm) highly doped Si with different superconductors (Sc) through point contact Andreev reflection (PCAR) spectroscopy. Spectra of low transparency point contacts between Si and In showed an enhancement in the superconducting energy gap of In.
arxiv +1 more source
Single-charge devices with ultrasmall Nb/AlOx/Nb trilayer Josephson junctions [PDF]
Josephson junction transistors and 50-junction arrays with linear junction dimensions from 200 nm down to 70 nm were fabricated from standard Nb/AlOx/Nb trilayers. The fabrication process includes electron beam lithography, dry etching, anodization, and planarization by chemical-mechanical polishing.
arxiv +1 more source
The beneficial effects of cumulus cells and oocyte-cumulus cell gap junctions depends on oocyte maturation and fertilization methods in mice [PDF]
Cumulus cells are a group of closely associated granulosa cells that surround and nourish oocytes. Previous studies have shown that cumulus cells contribute to oocyte maturation and fertilization through gap junction communication.
Cheng-Jie Zhou+9 more
doaj +2 more sources
Josephson effect in normal and ferromagnetic topological insulator planar, step and edge junctions [PDF]
We investigate Josephson junctions on the surface of a three-dimensional topological insulator in planar, step, and edge geometries. The elliptical nature of the Dirac cone representing the side surface states of the topological insulator results in a scaling factor in the Josephson current in a step junction as compared to the planar junction. In edge
arxiv +1 more source