Atrial fibrillation-linked germline GJA5/connexin40 mutants showed an increased hemichannel function. [PDF]
Mutations in GJA5 encoding the gap junction protein connexin40 (Cx40) have been linked to lone atrial fibrillation. Some of these mutants result in impaired gap junction function due to either abnormal connexin localization or impaired gap junction ...
Yiguo Sun +4 more
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Gap Junction-Dependent and -Independent Functions of Connexin43 in Biology
For the first time in animal evolution, the emergence of gap junctions allowed direct exchanges of cellular substances for communication between two cells.
Yi Zhu
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Novel Josephson effects between multi-gap and single-gap superconductors [PDF]
Multi-gap superconductors can exhibit qualitatively new phenomena due to existence of multiple order parameters. Repulsive electronic interactions may give rise to a phase difference of $\pi$ between the phases of the order parameters.
Abbitt J.D. +9 more
core +2 more sources
Atomic structure of the innexin-6 gap junction channel determined by cryo-EM
Innexins, a large protein family comprising invertebrate gap junction channels, play an essential role in nervous system development and electrical synapse formation.
A. Oshima, K. Tani, Y. Fujiyoshi
semanticscholar +1 more source
Critical gap analysis of merging sections at Kuala Lumpur middle ring road [PDF]
At merging sections, drivers normally slow down and sometimes need to stop while seeking a suitable gap before merging with the mainstream. Thus, there will always be several observed rejected gaps and an accepted gap which can be used to determine the ...
Hamid, N. B. +5 more
core +1 more source
Arrhythmogenic right ventricular cardiomyopathy: considerations from in silico experiments
Objective: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is associated with remodelling of gap junctions and also, although less well-defined, down-regulation of the fast sodium current. The gap junction remodelling and down-regulation of sodium
Ronald eWilders
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Gap Junction Blockers: An Overview of their Effects on Induced Seizures in Animal Models
: Background Gap junctions are clusters of intercellular channels allowing the bidirectional pass of ions directly into the cytoplasm of adjacent cells.
J. Manjarrez-Marmolejo +1 more
semanticscholar +1 more source
Gap junction networks in mushroom bodies participate in visual learning and memory in Drosophila
Gap junctions are widely distributed in the brains across species and play essential roles in neural information processing. However, the role of gap junctions in insect cognition remains poorly understood.
Qingqing Liu +6 more
semanticscholar +1 more source
Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies [PDF]
We examined the roles of the extracellular domains of a gap junction protein and a cell adhesion molecule in gap junction and adherens junction formation by altering cell interactions with antibody Fab fragments.
Johnson, Ross G. +3 more
core +2 more sources
A structural and functional comparison of gap junction channels composed of connexins and innexins
Methods such as electron microscopy and electrophysiology led to the understanding that gap junctions were dense arrays of channels connecting the intracellular environments within almost all animal tissues.
I. M. Skerrett, Jamal B. Williams
semanticscholar +1 more source

