Results 1 to 10 of about 149 (147)
Current Biology, 2013 In vertebrates and invertebrates, signaling among neurons is most commonly mediated by chemical synapses. At these synapses neurotransmitter released by presynaptic neurons is detected by receptors on the postsynaptic neurons, leading to an influx of ions through the receptors themselves or through channels activated by intracellular signaling ...
Shimizu, Kazumichi, Stopfer, Mark
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Cold Spring Harbor Perspectives in Biology, 2009 Gap junctions are aggregates of intercellular channels that permit direct cell-cell transfer of ions and small molecules. Initially described as low-resistance ion pathways joining excitable cells (nerve and muscle), gap junctions are found joining virtually all cells in solid tissues.
Daniel A, Goodenough, David L, Paul
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The Journal of Cell Biology, 2005 In the 1960s there was adhesion and there was direct current transfer—a strange neuronal phenomenon whose mechanism was unknown. The two fields only gradually drifted together, but with the report by Revel and Karnovsky (1967) they were united around a distinct, structural correlate soon to ...
William A, Wells, Laura, Bonetta
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Gap Junctions in Development [PDF]
American Zoologist, 1986 The concept of a multicellular organism as an assemblage of cells that work together harmoniously for the good of the whole organism is well established. Over the past 15 years, however, it has become increasingly clear that the individual cells of multicellular animals are not as self-sufficient and independent of each other as once had been believed.
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Gap junctions in C. elegans [PDF]
Frontiers in Physiology, 2014 As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that surprisingly share no primary sequence homology, but do share structural and functional similarity with ...
Karina eSimonsen +3 more
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On gap junction structure. [PDF]
The Journal of cell biology, 1980 We have studied the stain distribution within rat liver gap junctions for specimens prepared by thin sectioning and negative staining. Pools of stain molecules exist in two specific locations with respect to the distinctive morphological units (connexons) of the junction.
Guido A. Zampighi +2 more
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The Gap Junction Communication Channel [PDF]
Cell, 1996 We thank Nancy Kauler for her superb secretarial assistance. In addition, we are extremely grateful to Dr. Matthias Falk for his helpful comments concerning the content of this manuscript. Owing to restrictions on the number of references, selected original articles and reviews are cited.
Nalin M. Kumar, Norton B. Gilula
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Adrenocortical Gap Junctions and Their Functions [PDF]
Frontiers in Endocrinology, 2016 Adrenal cortical steroidogenesis and proliferation are thought to be modulated by gap junction-mediated direct cell-cell communication of regulatory molecules between cells. Such communication is regulated by the number of gap junction channels between contacting cells, the rate at which information flows between these channels, and the rate of channel
Sandra A. Murray, Cheryl L. Bell
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Gap Junctions and Cochlear Homeostasis [PDF]
Journal of Membrane Biology, 2006 Gap junctions play a critical role in hearing and mutations in connexin genes cause a high incidence of human deafness. Pathogenesis mainly occurs in the cochlea, where gap junctions form extensive networks between non-sensory cells that can be divided into two independent gap junction systems, the epithelial cell gap junction system and the connective
Anaclet Ngezahayo +3 more
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Stick with gap junctions [PDF]
The Journal of Cell Biology, 2007 ![][1] Without gap junctions, neurons (green) fail to migrate (left). Migration is restored (right) by junctions that adhere but have a closed pore. KRIEGSTEIN/MACMILLAN Gap junctions, known communications experts, are also skilled at adhesion, based on results from Laura Elias,
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