Results 191 to 200 of about 217,733 (290)

Endothelial-adipocyte Cx43 Mediated Gap Junctions Can Regulate Adiposity. [PDF]

Function (Oxf)
Luse MA, Dunaway LS, Nyshadham S, Carvalho A, Sedovy MW, Ruddiman CA, Tessema R, Hirschi K, Johnstone SR, Isakson BE.   +9 more
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Gap junctions allow transfer of metabolites between germ cells and somatic cells to promote germ cell growth in the Drosophila ovary. [PDF]

PLoS Biol
Vachias C, Tourlonias C, Grelée L, Gueguen N, Renaud Y, Venugopal P, Richard G, Pouchin P, Brasset E, Mirouse V.   +9 more
europepmc   +1 more source

Morphological analysis of cell distribution and network structure via gap junctions in swine corneal stroma. [PDF]

J Vet Med Sci, 2022
Hoshino N, Takehana K, Hosotani M, Kametani K, Iwasaki T, Hasegawa Y, Ueda H, Watanabe T.   +7 more
europepmc   +1 more source

Gap Junction [PDF]

, 2020
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Rat Hepatocytes Mitigate Cadmium Toxicity by Forming Annular Gap Junctions and Degrading Them via Endosome-Lysosome Pathway. [PDF]

Int J Mol Sci, 2022
Yuan J, Huang X, Zhao Y, Gu J, Yuan Y, Liu Z, Zou H, Bian J.   +7 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Bridging the Gap: How Endothelial-Adipocyte Cx43 Mediated Gap Junctions Could Revolutionize Adiposity Regulation. [PDF]

Function (Oxf)
Vezza T, Víctor VM.
europepmc   +1 more source

Downregulation of connexin 43-based gap junctions underlies propofol-induced excessive relaxation in hypertensive vascular smooth muscle cells. [PDF]

Cell Commun Signal, 2023
Zeng W, Deng Z, Gao Y, Sun G, Li X, Yuan D.   +5 more
europepmc   +1 more source