Results 201 to 210 of about 73,986 (253)

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker   +9 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Gap Junctions

Comprehensive Physiology, 2012
AbstractGap junctions are essential to the function of multicellular animals, which require a high degree of coordination between cells. In vertebrates, gap junctions comprise connexins and currently 21 connexins are known in humans. The functions of gap junctions are highly diverse and include exchange of metabolites and electrical signals between ...
Nielsen, Morten Schak   +5 more
  +6 more sources

Gap Junctional Communication

Annual Review of Physiology, 1981
The formation of low resistance pathways is one of the most common forms of cellular interaction. Since its discovery between neurons (40) this form of cell-to-cell communication has been documented widely in both excitable and nonexcitable cells.
E L, Hertzberg   +2 more
openaire   +2 more sources

Invertebrate gap junctions

Journal of Cell Science, 1977
ABSTRACT Both glycerol and glutaraldehyde, the two most commonly used chemical aids in freeze-fracture studies, have been shown individually to affect the structure of certain membranes as observed in freeze-fracture replicas. The present investigation studied the effect of glycerol on the gap junctions found in a number of tissues from ...
openaire   +2 more sources

The gap junction

Journal of Cell Science, 1988
ABSTRACT Gap junctions are intercellular structures that link cells and allow them to exchange ions and small metabolites without recourse to the extracellular space (for reviews and early references, see Goodenough, 1979; Loewen-stein, 1981).
openaire   +2 more sources

Gap Junctions and Ageing

2023
Gap junctions, comprising connexin proteins, create conduits directly coupling the cytoplasms of adjacent cells. Expressed in essentially all tissues, dynamic gap junction structures enable the exchange of small molecules including ions and second messengers, and are central to maintenance of homeostasis and synchronized excitability. With such diverse
Michael J, Zeitz, James W, Smyth
openaire   +2 more sources

Chemistry of Gap Junctions

Annual Review of Physiology, 1985
Gap junctions [also called nexus (15) or maculae communicantes (102)] repre­ sent transcellular channels that permit the exchange of small molecules and ions between neighboring cells (28, 33, 74, 75, 82, 86, 89, 103). They differ from other membrane channels in a number of respects: they provide a pathway between cells rather than across one cell ...
Revel, J.-P.   +2 more
openaire   +3 more sources

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