Results 151 to 160 of about 15,677 (174)
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Role of Gasdermin E mediated cell death during colorectal carcinogenesis
2023Der Zelltod hat zentrale Funktionen in der Entwicklung und in der Homöostase adulter Gewebestrukturen. Dabei werden dysregulierte Zelltodprozesse mit der Entstehung zahlreicher menschlicher Krankheiten, einschließlich Krebs und Entzündungen in Verbindung gebracht.
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Caspase-3/Gasdermin E-mediated pyroptosis contributes to Ricin toxin-induced inflammation
Toxicology LettersRicin toxin (RT) is highly cytotoxic and can release a considerable amount of pro-inflammatory factors due to depurination, causing excessive inflammation that may aggravate the harm to the body. Pyroptosis, a type of gasdermin-mediated cell death, is a contributor to the exacerbation of inflammation.
Yuxin, Xu +9 more
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2A2 protein of DHAV-1 induces duck embryo fibroblasts gasdermin E-mediated pyroptosis
Veterinary MicrobiologyThe duck hepatitis A virus type 1 (DHAV-1) causes rapid death in ducklings by triggering a severe cytokine storm. Pyroptosis is an inflammatory form of programmed cell death that is directly related to an increase in pro-inflammatory cytokine levels. Only a few studies have explored the mechanisms underlying pyroptosis in virus-infected avian cells. In
Jingyu, Wang +4 more
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Insight into the structure, function and the tumor suppression effect of gasdermin E
Biochemical PharmacologyGasdermin E (GSDME), which is also known as DFNA5, was first identified as a deafness-related gene that is expressed in cochlear hair cells, and mutation of this gene causes autosomal dominant neurogenic hearing loss. Later studies revealed that GSDME is mostly expressed in the kidney, placenta, muscle and brain cells, but it is expressed at low levels
Yuge, Long, Xiaoyuan, Jia, Liang, Chu
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Developing Detection Tools for Gasdermin E
Genetic Engineering & Biotechnology News, 2018openaire +1 more source
The gasdermin protein family: emerging roles in gastrointestinal health and disease
Nature Reviews Gastroenterology and Hepatology, 2023Giuseppe Privitera +2 more
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[Research process of Gasdermin E in inducing cell pyroptosis].
Zhonghua bing li xue za zhi = Chinese journal of pathology, 2021Y Y, Yang, X P, Liu
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Mechanistic Insights into Gasdermin Pore Formation and Regulation in Pyroptosis
Journal of Molecular Biology, 2022Chengliang Wang, Jianbin Ruan
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