Results 1 to 10 of about 743,593 (306)
Distinguishing epigenetic marks of developmental and imprinting regulation [PDF]
Epigenetics & Chromatin, 2010 Background The field of epigenetics is developing rapidly, however we are only beginning to comprehend the complexity of its influence on gene regulation.
McEwen Kirsten R, Ferguson-Smith Anne C
doaj +5 more sources
The p53 gene expression and its developmental regulation in schistosomes [PDF]
Memorias do Instituto Oswaldo Cruz, 1992 We have studied the gene expression, especially of the oncoproteins, and its regulation in schistosomes. Schistosomes have a complex life cycle with defined dimorphic lifestyle. The parasite are so far unique in biology in expressing oncogene products in
Manami Tanaka +2 more
doaj +4 more sources
Developmental regulation of GABAergic gene expression in forebrain cholinergic neurons
Frontiers in Neural Circuits, 2023 Acetylcholine and GABA are often co-released, including from VIP-expressing neurons of the cortex, cortically-projecting neurons of the globus pallidus externus and basal forebrain, and hippocampal-projecting neurons of the medial septum.
Adam J. Granger +4 more
doaj +3 more sources
Expression of myogenic, growth related, mitochondrial and antioxidant genes across developmental stage, muscle type, and genotype in Japanese quail skeletal muscle [PDF]
Poultry ScienceThis study examined the developmental and genotype dependent expression of key myogenic (MYOD1, MYOG, PAX7), growth related (IGF1, GHR, MSTN), mitochondrial (ANT, COXIII, UCP), and antioxidant (SOD1, CAT) genes in skeletal muscles of Japanese quail ...
Gonca Sonmez +3 more
doaj +2 more sources
Thermal and developmental regulation of gene expression in Trypanosoma cruzi [PDF]
Memorias do Instituto Oswaldo Cruz, 1988 C. M. A. Soares +6 more
doaj +4 more sources
Frontiers in Cell and Developmental Biology, 2023 Maternal diabetes and obesity in pregnancy are well-known risk factors for structural birth defects, including neural tube defects and congenital heart defects.
Man Zhang +4 more
doaj +1 more source
Global Gene Expression Profiling of Individual Human Oocytes and Embryos Demonstrates Heterogeneity in Early Development [PDF]
, 2013 Early development in humans is characterised by low and variable embryonic viability, reflected in low fecundity and high rates of miscarriage, relative to other mammals.
Brison, Daniel R. +4 more
core +11 more sources
Frontiers in Cell and Developmental Biology, 2022 Maternal diabetes in early pregnancy increases the risk for birth defects in the offspring, particularly heart, and neural tube defects. While elevated glucose levels are characteristic for diabetic pregnancies, these are also accompanied by ...
Claudia Kappen +3 more
doaj +1 more source
Broad spectrum of CRISPR-induced edits in an embryonic lethal gene
Scientific Reports, 2021 Mendelian genetics poses practical limitations on the number of mutant genes that can be investigated simultaneously for their roles in embryonic development in the mouse.
Kayla T. B. Fuselier +2 more
doaj +1 more source
Cell Reports, 2021 Summary: The ARID1A subunit of SWI/SNF chromatin remodeling complexes is a potent tumor suppressor. Here, a degron is applied to detect rapid loss of chromatin accessibility at thousands of loci where ARID1A acts to generate accessible minidomains of ...
Seraina Blümli +13 more
doaj +1 more source