Results 11 to 20 of about 918,759 (321)
Nature Communications, 2022 Our understanding of the extent of involvement of DNA methylation in genome-wide gene regulation and plant developmental control is incomplete. Here, the authors knock out all five known DNA methyltransferases and show the developmental and gene ...
Li He +8 more
doaj +2 more sources
Developmental regulation of lck gene expression in T lymphocytes. [PDF]
The Journal of experimental medicine, 1991 In the mouse and human, mRNA transcripts encoding the lymphocyte-specific protein tyrosine kinase p56lck are derived from two separate promoters resulting in heterogeneity in the 5' untranslated region sequence. The proximal promoter lies just 5' to the coding region for the gene and is active only in thymocytes.
Roger M. Perlmutter +8 more
openaire +4 more sources
PLoS ONE, 2013 Diacylglycerol acyltransferases (DGAT) catalyze the final and rate-limiting step of triacylglycerol (TAG) biosynthesis in eukaryotic organisms. DGAT genes have been identified in numerous organisms. Multiple isoforms of DGAT are present in eukaryotes. We
Heping Cao +5 more
doaj +2 more sources
Developmental regulation of trypanosome mitochondrial gene expression.
Journal of Biological Chemistry, 1987 Mitochondrial respiratory activities in the protozoan parasite Trypanosoma brucei are developmentally regulated. The trypanosomes in the mammalian bloodstream derive ATP entirely from glycolysis. The trypanosomes found in the midgut of the insect vector or in culture at 26 degrees C have fully functional mitochondria with cytochrome-mediated ...
Stephen L. Hajduk, Emil F. Michelotti
openaire +4 more sources
A Generalized Linear Model for Decomposing Cis-regulatory, Parent-of-Origin, and Maternal Effects on Allele-Specific Gene Expression [PDF]
G3: Genes, Genomes, Genetics, 2017 Joint quantification of genetic and epigenetic effects on gene expression is important for understanding the establishment of complex gene regulation systems in living organisms. In particular, genomic imprinting and maternal effects play important roles
Yasuaki Takada +4 more
doaj +2 more sources
DNA methylation and regulation of gene expression: Guardian of our health
The Nucleus, 2021 One of the most critical epigenetic signatures present in the genome of higher eukaryotes is the methylation of DNA at the C-5 position of the cytosine ring.
Gaurab Aditya Dhar +3 more
semanticscholar +1 more source
Developmental regulation and expression of the zebrafish connexin43 gene [PDF]
Developmental Dynamics, 2005 AbstractWe cloned and sequenced the zebrafish (Danio rerio) connexin43 (Cx43α1) gene. The predicted protein sequence shows a high degree of sequence conservation. Transcript analyses revealed multiple transcription start sites and a potential alternative transcript encoding a N‐terminally truncated Cx43α1 protein.
Carla Finis +13 more
openaire +3 more sources
Nature Communications, 2020 Coordinated chromatin interactions between enhancers and promoters are critical for gene regulation. The architectural protein CTCF mediates chromatin looping and is enriched at the boundaries of topologically associating domains (TADs), which are sub ...
Martin Franke +8 more
semanticscholar +1 more source
Brain Sciences, 2023 Development is a complex process involving precise regulation. Developmental regulation may vary in tissues and individuals, and is often altered in disorders.
Yuqiu Zhou, Li Tao, Ying Zhu
doaj +1 more source
chHDAC11 mRNA Expression During Prenatal and Postnatal Chicken (Gallus gallus) Brain Development
Caspian Journal of Neurological Sciences, 2022 Background: Histone deacetylation plays an essential role in transcriptional regulation of cell cycle progression and other evolutionary processes. Several results confirm the importance of the latest found HDAC11 gene to deacetylate histone core in ...
Farzam Ajamian +4 more
doaj +1 more source