Results 11 to 20 of about 743,593 (306)
Differential responses to maternal diabetes in embryo and visceral yolk sac
Introduction: Maternal diabetes during pregnancy is well known to be associated with a higher risk for structural birth defects in the offspring. Recent searches for underlying mechanisms have largely focused on aberrant processes in the embryo itself ...
J. Michael Salbaum +3 more
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Developmental Regulation of Angiotensinogen Gene Expression in Sheep [PDF]
It has been suggested that the liver is not the main source of angiotensinogen during fetal life in rats, but that the kidney is an important site of fetal angiotensinogen synthesis. In an effort to determine if this phenomenon is specific to the rat or applicable to other species, we compared the ontogenic changes in hepatic and renal angiotensinogen ...
Olson, Ann Louise +2 more
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Development is a complex process involving precise regulation. Developmental regulation may vary in tissues and individuals, and is often altered in disorders.
Yuqiu Zhou, Li Tao, Ying Zhu
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chHDAC11 mRNA Expression During Prenatal and Postnatal Chicken (Gallus gallus) Brain Development
Background: Histone deacetylation plays an essential role in transcriptional regulation of cell cycle progression and other evolutionary processes. Several results confirm the importance of the latest found HDAC11 gene to deacetylate histone core in ...
Farzam Ajamian +4 more
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BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes
Protein Phosphatase 2A (PP2A) is a heterotrimer composed of scaffolding (A), catalytic (C), and regulatory (B) subunits. PP2A complexes with B56 subunits are targeted by Shugoshin and BUBR1 to protect centromeric cohesion and stabilise kinetochore ...
Laura Bel Borja +9 more
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Mutations in the ARID1B subunit of the BAF chromatin remodeling complex are associated with the neurodevelopmental Coffin-Siris syndrome. Here the authors reveal that there is a transition from ARID1A-containing complexes to ARID1B during cranial neural ...
Luca Pagliaroli +14 more
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The regulation of Hox gene expression during animal development [PDF]
Hox genes encode a family of transcriptional regulators that elicit distinct developmental programmes along the head-to-tail axis of animals. The specific regional functions of individual Hox genes largely reflect their restricted expression patterns ...
Alonso, Claudio R, Mallo, Moisés
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Genetic variation in voltage-gated sodium (NaV) channels is a significant contributor to neurodevelopmental disorders. NaV channel alpha subunits are encoded by the SCNxA family and four are predominately expressed in the brain: SCN1A, SCN2A, SCN3A, and ...
Jacqueline Heighway +8 more
doaj +1 more source
Stochastic neural network models for gene regulatory networks [PDF]
Recent advances in gene-expression profiling technologies provide large amounts of gene expression data. This raises the possibility for a functional understanding of genome dynamics by means of mathematical modelling.
Burrage, K., Tian, T.
core +2 more sources
Developmental regulation and expression of the zebrafish connexin43 gene [PDF]
AbstractWe cloned and sequenced the zebrafish (Danio rerio) connexin43 (Cx43α1) gene. The predicted protein sequence shows a high degree of sequence conservation. Transcript analyses revealed multiple transcription start sites and a potential alternative transcript encoding a N‐terminally truncated Cx43α1 protein.
Bishwanath, Chatterjee +12 more
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