Results 21 to 30 of about 743,593 (306)

Recent advances in signal integration mechanisms in the unfolded protein response [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Since its discovery more than 25 years ago, great progress has been made in our understanding of the unfolded protein response (UPR), a homeostatic mechanism that adjusts endoplasmic reticulum (ER) function to satisfy the physiological demands of the ...
G. Elif Karagöz   +2 more
doaj   +1 more source

Transcription of satellite DNAs in insects [PDF]

open access: yes, 2011
Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic   +3 more
core   +1 more source

Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos

open access: yeseLife, 2020
Ascidians with very similar embryos but highly divergent genomes are thought to have undergone extensive developmental system drift. We compared, in four species (Ciona and Phallusia for Phlebobranchia, Molgula and Halocynthia for Stolidobranchia), gene ...
Joshua F Coulcher   +8 more
doaj   +1 more source

Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]

open access: yes, 2017
Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani   +5 more
core   +1 more source

A chicken homeo box gene with developmentally regulated expression [PDF]

open access: yesFEBS Letters, 1989
Several homeo box sequences were isolated from a chicken (Gallus domesticus) genomic library. One phage, λGG7, was chosen for further study and the single homeo box sequence it contains was characterized. The sequence of the homeo box revealed it to be a distant member of the Antp class of homeo boxes.
Fainsod, Abraham, Gruenbaum, Yosef
openaire   +2 more sources

Developmental regulation of proenkephalin gene expression in osteoblasts. [PDF]

open access: yesMolecular Endocrinology, 1995
Proenkephalin (PENK), a classically defined opioid gene, was originally thought to be expressed almost exclusively in the mature nervous and neuroendocrine systems. In the last few years, it was demonstrated, however, that high levels of PENK messenger RNA and PENK-derived peptides are expressed in embryonic mesenchymal tissues during differentiation ...
H, Rosen   +4 more
openaire   +3 more sources

Dynamic association of NUP98 with the human genome. [PDF]

open access: yesPLoS Genetics, 2013
Faithful execution of developmental gene expression programs occurs at multiple levels and involves many different components such as transcription factors, histone-modification enzymes, and mRNA processing proteins.
Yun Liang   +4 more
doaj   +1 more source

A connection between stress and development in the multicelular prokaryote Streptomyces coelicolor [PDF]

open access: yes, 2001
Morphological changes leading to aerial mycelium formation and sporulation in the mycelial bacterium Streptomyces coelicolor rely on establishing distinct patterns of gene expression in separate regions of the colony.
Bucca G.   +24 more
core   +1 more source

Mapping Native R-Loops Genome-wide Using a Targeted Nuclease Approach

open access: yesCell Reports, 2019
Summary: R-loops are three-stranded DNA:RNA hybrids that are implicated in many nuclear processes. While R-loops may have physiological roles, the formation of stable, aberrant R-loops has been observed in neurological disorders and cancers.
Qingqing Yan   +3 more
doaj   +1 more source

Poly(ADP-ribosyl)ating enzymes cooperate to coordinate development

open access: yesScientific Reports, 2022
The transcriptome is subject to rapid and massive changes during the transition between developmental stages. These changes require tight control to avoid the undesired reactivation of gene expression that is only important for previous developmental ...
Guillaume Bordet   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy