Results 31 to 40 of about 918,759 (321)
A compartmentalized regulator of developmental gene expression in Bacillus subtilis [PDF]
We have identified a new Bacillus subtilis gene, spoVT, whose gene product is homologous to the transcriptional regulator AbrB and serves as a regulator of E sigmaG-controlled gene expression. SpoVT acts both positively and negatively in controlling sigmaG-dependent gene expression, providing an additional level of refinement to forespore gene ...
Simon M. Cutting, J Hobot, I Bagyan
openaire +3 more sources
Poly(ADP-ribosyl)ating enzymes cooperate to coordinate development
The transcriptome is subject to rapid and massive changes during the transition between developmental stages. These changes require tight control to avoid the undesired reactivation of gene expression that is only important for previous developmental ...
Guillaume Bordet+2 more
doaj +1 more source
BackgroundTo identify the genes involved in the development of low temperature (LT) tolerance in hexaploid wheat, we examined the global changes in expression in response to cold of the 55,052 potentially unique genes represented in the Affymetrix Wheat ...
D. Laudencia‐Chingcuanco+5 more
semanticscholar +1 more source
An explanatory evo-devo model for the developmental hourglass [PDF]
The "developmental hourglass" describes a pattern of increasing morphological divergence towards earlier and later embryonic development, separated by a period of significant conservation across distant species (the "phylotypic stage"). Recent studies have found evidence in support of the hourglass effect at the genomic level.
arxiv +1 more source
mRNA Cap Methylation in Pluripotency and Differentiation
The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating
Laura Grasso+9 more
doaj +1 more source
Developmental regulation of rat brain/Hep G2 glucose transporter gene expression.
The developmental regulation of rat brain-derived/Hep G2 glucose transporter gene expression was studied by means of Northern blot hybridization, using a rat brain glucose transporter cDNA probe, in order to directly quantify steady state glucose ...
Haim Werner+4 more
semanticscholar +1 more source
Developmental regulation of somatostatin gene expression in the brain is region specific.
Developmental regulation of somatostatin (SRIF) gene expression was studied in five regions of rat brain and in rat stomach. Total RNA was isolated from hypothalamus, cortex, brainstem, cerebellum, and olfactory bulb, as well as stomach at eight stages ...
William L. Lowe+3 more
semanticscholar +1 more source
Role of Topoisomerase IIβ in the Expression of Developmentally Regulated Genes [PDF]
Mice lacking topoisomerase IIbeta (TopIIbeta) are known to exhibit a perinatal death phenotype. In the current study, transcription profiles of the brains of wild-type and top2beta knockout mouse embryos were generated. Surprisingly, only a small number (1 to 4%) of genes were affected in top2beta knockout embryos. However, the expression of nearly 30%
Yi Lisa Lyu+5 more
openaire +3 more sources
Summary: The ARID1A subunit of SWI/SNF chromatin remodeling complexes is a potent tumor suppressor. Here, a degron is applied to detect rapid loss of chromatin accessibility at thousands of loci where ARID1A acts to generate accessible minidomains of ...
Seraina Blümli+13 more
doaj
Optogenetic Control of Gene Expression in Drosophila. [PDF]
To study the molecular mechanism of complex biological systems, it is important to be able to artificially manipulate gene expression in desired target sites with high precision.
Yick-Bun Chan+2 more
doaj +1 more source