RNA interference in marine and freshwater sponges [PDF]
Background: The marine sponge Tethya wilhelma and the freshwater sponge Ephydatia muelleri are emerging model organisms to study evolution, gene regulation, development, and physiology in non-bilaterian animal systems. Thus far, functional methods (i.e.,
Cieniewicz, Brandon +12 more
core +1 more source
Our understanding of the extent of involvement of DNA methylation in genome-wide gene regulation and plant developmental control is incomplete. Here, the authors knock out all five known DNA methyltransferases and show the developmental and gene ...
Li He +8 more
doaj +1 more source
mRNA Cap Methylation in Pluripotency and Differentiation
The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating
Laura Grasso +9 more
doaj +1 more source
Transcriptome sequencing and developmental regulation of gene expression in Anopheles aquasalis. [PDF]
BACKGROUND:Anopheles aquasalis is a major malaria vector in coastal areas of South and Central America where it breeds preferentially in brackish water.
André L Costa-da-Silva +12 more
doaj +1 more source
Disruption of the developmental programme of Trypanosoma brucei by genetic ablation of TbZFP1, a differentiation-enriched CCCH protein [PDF]
The regulation of differentiation is particularly important in microbial eukaryotes that inhabit multiple environments. The parasite Trypanosoma brucei is an extreme example of this, requiring exquisite gene regulation during transmission from mammals to
Hendriks, Edward F, Matthews, Keith R
core +1 more source
Regulation of globin gene expression: boxes and borders [PDF]
The experimental work presented in this thesis pertains to the regulation of gene expression and focuses on the regulation of the B globin genes. The expression of the globin genes is restricted to the erythropoietic tissue and is regulated during ...
Zafarana, G. (Gaetano)
core +6 more sources
Conservation and co-option in developmental programmes: the importance of homology relationships [PDF]
One of the surprising insights gained from research in evolutionary developmental biology (evo-devo) is that increasing diversity in body plans and morphology in organisms across animal phyla are not reflected in similarly dramatic changes at the level ...
Becker, May-Britt +3 more
core +4 more sources
Optogenetic Control of Gene Expression in Drosophila. [PDF]
To study the molecular mechanism of complex biological systems, it is important to be able to artificially manipulate gene expression in desired target sites with high precision.
Yick-Bun Chan +2 more
doaj +1 more source
Sphingosine Phosphate Lyase Expression Is Essential for Normal Development in Caenorhabditis elegans [PDF]
Sphingolipids are ubiquitous membrane constituents whose metabolites function as signaling molecules in eukaryotic cells. Sphingosine 1-phosphate, a key sphingolipid second messenger, regulates proliferation, motility, invasiveness, and programmed cell ...
Fyrst, Henrik +3 more
core +1 more source
Developmental regulation of trypanosome mitochondrial gene expression.
Mitochondrial respiratory activities in the protozoan parasite Trypanosoma brucei are developmentally regulated. The trypanosomes in the mammalian bloodstream derive ATP entirely from glycolysis. The trypanosomes found in the midgut of the insect vector or in culture at 26 degrees C have fully functional mitochondria with cytochrome-mediated ...
E F, Michelotti, S L, Hajduk
openaire +2 more sources

