Results 41 to 50 of about 918,759 (321)
Developmental regulation of myosin gene expression in mouse cardiac muscle
Journal of Cell Biology, 1990 Expression of the two isoforms of cardiac myosin heavy chain (MHC), MHC alpha and MHC beta, in mammals is regulated postnatally by a variety of stimuli, including serum hormone levels.
G. Lyons +4 more
semanticscholar +1 more source
Quantitative Modelling of Diffusion-driven Pattern Formation in microRNA-regulated Gene Expression [PDF]
arXiv, 2023 MicroRNAs are extensively known for post-transcriptional gene regulation and pattern formation in the embryonic developmental stage. We explore the origin of these spatio-temporal patterns mathematically, considering three different motifs here.
arxiv
PLoS Neglected Tropical Diseases, 2022 BackgroundAedes albopictus originated in the tropical forests of Southeast Asia and can currently be found on all continents. As one of the main arboviral vectors, the control of Ae.
Wenjuan Liu +5 more
doaj +1 more source
MicroRNAs Instruct and Maintain Cell Type Diversity in the Nervous System
Frontiers in Molecular Neuroscience, 2021 Characterizing the diverse cell types that make up the nervous system is essential for understanding how the nervous system is structured and ultimately how it functions.
Norjin Zolboot +4 more
doaj +1 more source
Endocrinology, 2004 The TSH receptor plays a pivotal role in thyroid gland growth, function, and differentiation in the mature animal, but only recently has its role in the fetus and neonate been examined.
Rosalind S. Brown
semanticscholar +1 more source
Robustness under functional constraint: The genetic network for temporal expression in Drosophila neurogenesis [PDF]
, 2009 Precise temporal coordination of gene expression is crucial for many developmental processes. One central question in developmental biology is how such coordinated expression patterns are robustly controlled. During embryonic development of the Drosophila central nervous system, neural stem cells called neuroblasts sequentially express a group of genes
arxiv +1 more source
Homeorhesis in Waddington's Landscape by Epigenetic Feedback Regulation [PDF]
Phys. Rev. Research 2, 023083 (2020), 2019 In multicellular organisms, cells differentiate into several distinct types during early development. Determination of each cellular state, along with the ratio of each cell type, as well as the developmental course during cell differentiation are highly regulated processes that are robust to noise and environmental perturbations throughout development.
arxiv +1 more source
Cooperation, cis-interactions, versatility and evolutionary plasticity of multiple cis-acting elements underlie krox20 hindbrain regulation. [PDF]
PLoS Genetics, 2018 Cis-regulation plays an essential role in the control of gene expression, and is particularly complex and poorly understood for developmental genes, which are subject to multiple levels of modulation.
Patrick Torbey +8 more
doaj +1 more source
Three facets of mathematical cancer biology research [PDF]
arXiv, 2023 Cancer, as the uncontrollable cell growth, is related to many branches of biology. In this review, we will discuss three mathematical approaches for studying cancer biology: population dynamics, gene regulation, and developmental biology. If we understand all biochemical mechanisms of cancer cells, we can directly calculate how the cancer cell ...
arxiv
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source