Results 31 to 40 of about 9,231 (134)
HIV Medicine, EarlyView.Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre +2 more
wiley +1 more source
Sex Differences in Response to Viral Vector Vaccines—Implications for Future Vaccine Design
Immunological Reviews, Volume 338, Issue 1, March 2026.ABSTRACT Vaccination represents one of the most impactful public health achievements, preventing 3.5 to 5 million deaths annually according to estimates of the World Health Organization. Yet, recent outbreaks of emerging and reemerging infectious diseases highlight the need for rapid and strategic vaccine development using vaccine platforms ...
Ilka Grewe +2 more
wiley +1 more source
Advanced Science, Volume 13, Issue 8, 9 February 2026.Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li +3 more
wiley +1 more source
Matching Multiple Backgrounds: Egg Camouflage Across Different Habitats in a Shorebird
Ecology and Evolution, Volume 16, Issue 1, January 2026.We studied egg camouflage in Kentish plovers nesting in two visually distinct habitats, sandy beaches and salt marshes, in southern Spain. Despite initial expectations of local adaptation or compromise camouflage, the birds instead chose nest sites within each habitat that shared overlapping colour and visual texture characteristics, allowing effective
Alexandra Grandón‐Ojeda +4 more
wiley +1 more source
Acute Heat Priming Dampens Gene Expression Response to Thermal Stress in a Widespread Acropora Coral
Ecology and Evolution, Volume 16, Issue 1, January 2026.(a) Experimental design. Corals from 10 genotypes were distributed across two experimental blocks, each containing nine flow‐through tanks. Fragments from five genotypes were placed in each tank. (b) Temperature profiles and sampling time points in the heat stress assay, demonstrating ramp up from control conditions (27ºC, MMM) to the preconditioning ...
Declan J. A. Stick +5 more
wiley +1 more source
Enhancing HIV-1 Nef Penetration into Mammalian Cells as an Antigen Candidate
Journal of Medical Microbiology and Infectious Diseases, 2019 Introduction: The human immunodeficiency virus type 1 (HIV-1) Nef regulatory protein is known as a candidate for the design of therapeutic HIV DNA and protein vaccines.
Saba Davoodi +3 more
doaj
Trained Immunity and Cardiovascular Risk: An Immunological Perspective
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT Systemic inflammation is a key driver of atherogenesis and its complications. While anti‐inflammatory therapies targeting pathways such as IL‐1β and IL‐6 have shown promise in established atherosclerotic cardiovascular disease (ASCVD), potential systemic effects raise concerns about immune suppression and infection, underscoring the need for ...
Katherine A. Boden +3 more
wiley +1 more source
Advanced Science, Volume 12, Issue 45, December 4, 2025.To enable mitotic spindle assembly during cell division, centrosomes must bear tensile stresses generated by microtubule‐mediated pulling forces. Micro‐rheology reveals that PLK‐1 phosphorylation of the scaffold protein SPD‐5 tunes the viscoelasticity, size, and morphology of the centrosome scaffold in C. elegans.
Matthew Amato +5 more
wiley +1 more source
Journal of Comparative Neurology, Volume 533, Issue 12, December 2025.Using projection‐ and layer‐specific rabies tracing, we mapped brain‐wide inputs to multiple feedforward and feedback neuron types in VISl (LM), the mouse secondary visual cortex. Although input patterns were broadly similar across neuron types, we observed differences in the relative contributions of visual, retrosplenial, and auditory cortices ...
Richard G. Dickson +6 more
wiley +1 more source
Deciphering epigenetic regulation in postmenopausal osteoporosis: Current and future perspectives
VIEW, Volume 6, Issue 6, December 2025.In this perspective, the significant roles of microRNAs, long noncoding RNAs and circular RNAs in postmenopausal osteoporosis are thoroughly expounded. The advantages and limitations of typical noncoding RNAs as diagnostic biomarkers and therapeutic targets are summarized and discussed.
Xiumei Tang +10 more
wiley +1 more source