Results 151 to 160 of about 1,715,615 (239)

Comprehensive Genomic Profiling Reveals the Mutational Spectrum and Clinical Significance of BRCA1/2 and Other Cancer-Susceptibility Genes in Breast Cancer Patients from Southern Tunisia. [PDF]

Cancers (Basel)
Ammous-Boukhris N, Abdelmaksoud-Dammak R, Ben Kridis W, Ben-Ayed-Guerfali D, Guidara S, Feki A, Kamoun H, Khanfir A, Daoud J, Lizard GH, Gargouri A, Mokdad-Gargouri R.   +11 more
europepmc   +1 more source

Genes Involved in the Cisplatin Response of BRCA2 Cancers

, 2012
Breast and ovarian cancers are two of the most prevalent types of cancer in women and kill over 55,000 people annually in the US alone. A number of these cases are deficient in BRCA1 or 2, tumor suppressor genes involved in DNA repair.
Rose, Juliana Mary
core   +1 more source

Breast-Ovarian Hereditary Cancer Syndrome: Beyond <i>BRCA1</i> and <i>BRCA2</i>. [PDF]

Curr Oncol
Imyanitov E, Sokolenko A.
europepmc   +1 more source

STN1 upregulation promotes PARPi resistance in BRCA2-deficient cancer cells via replication fork protection and suppression of ssDNA gap formation. [PDF]

NAR Cancer
Laghari ZA, Li N, Gayybov S, Wang QE, Chai W.   +4 more
europepmc   +1 more source

Pathogenic germline variants in BRCA1/2 are associated with a decreased number of hypomethylated rDNA copies. [PDF]

Breast Cancer Res
Kießling S, Durackova J, Michler A, Geisen ABC, Santana Acevedo N, Haaf T.   +5 more
europepmc   +1 more source

Double heterozygous germline pathogenic variants in patients referred to a tertiary cancer genetics clinic in Singapore. [PDF]

Front Oncol
Wong RSJ, Ong PY, Ow SGW, Walsh RJ, Chan G, Lim VPY, Lee SC.   +6 more
europepmc   +1 more source

Predisposición genética para el cáncer de mama: genes BRCA1 y BRCA2 Genetic predisposition for breast cancer: BRCA1 and BRCA2 genes

, 2011
El descubrimiento de los genes BRCA1 y BRCA2 ha llevado a la introducción de pruebas genéticas cada vez más sofisticadas para medir el riesgo de cáncer de mama de origen hereditario, entre otras cosas.
Adriana A Rodríguez, Steven A Narod
core  

Comparative phylogenetic analysis of breast cancer susceptibility genes reveals evolutionary conservation supporting diagnostic barcode design. [PDF]

Ann Med Surg (Lond)
Rehman SU.
europepmc   +1 more source

A Multiplex RT-QPCR Assay of ONECUT2, EZH2, and BRCA2 for the Detection of Clinically Significant Prostate Cancer in Needle Biopsies. [PDF]

Cancers (Basel)
Inoue Y, Cen SY, Kaneko M, Yuan G, Deng Z, Lu R, Gong MC, Zhang J, Eskenazi F, Konganige S, Aron M, Sekino Y, Iwata T, Fujihara A, Ukimura O, Gill I, Abreu AL, Liang G.   +17 more
europepmc   +1 more source

<i>BRCA1</i> Gene as a Potential Marker for Lung Cancer Therapy. [PDF]

Int J Mol Sci
Tsyganov MM, Tsydenova IA, Dolgasheva DS, Ibragimova MK.   +3 more
europepmc   +1 more source