Results 151 to 160 of about 44,727 (269)
Aging and Cancer, Volume 7, Issue 2, Page 77-84, June 2026.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Advanced Science, Volume 13, Issue 35, 24 June 2026.This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey +6 more
wiley +1 more source
Cancer Innovation, Volume 5, Issue 3, June 2026.This consensus, based on the latest evidence‐based medical data, provides guidance on the standardized application and safety management of PARP inhibitors in breast cancer treatment, aiming to serve as a reference for clinical practice. ABSTRACT Breast cancer represents a major threat to women's health in China.
Fei Ma +5 more
wiley +1 more source
Caracterização das mutações dos genes BRCA1 e BRCA2
, 2012 Mestrado em Biologia Molecular e CelularO cancro da mama é o tipo de neoplasia maligna mais incidente nas mulheres a nível mundial. Na maior parte dos casos tem origem esporádica, mas estima-se que cerca de 7% tem origem hereditária, relacionada com a
Batista, Rui Pedro Monteiro
core
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Objective To investigate the prevalence, characteristics, and clinical implications of germline mutations in a consecutive cohort of Chinese colorectal cancer (CRC) patients, providing insights that may inform population‐specific genetic testing strategies.
Liting Lu +8 more
wiley +1 more source
Comprehensive Genomic Profiles of Patients With Biliary Tract Cancer
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Purpose Biliary tract cancer (BTC) represents a heterogeneous disease with highly lethal malignancy and poor clinical outcomes. Here, we aimed to evaluate its genomic profiles to promote the development of precision medicine for BTC. Materials and Methods Genomic analysis of 134 BTC patients was performed by using targeted panel sequencing in ...
Xia Yang +4 more
wiley +1 more source
Metachronous Primary Pancreatic Neuroendocrine Tumor and Adenocarcinoma: A Case Report
Cancer Reports, Volume 9, Issue 6, June 2026.ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with most patients presenting with advanced disease. Surgical resection remains the only potentially curative option, yet recurrence rates are high. Case We present a rare case of metachronous primary pancreatic neuroendocrine tumor (PanNET) and PDAC in a 71‐year‐old ...
Anastasia S. Fatyanova +7 more
wiley +1 more source
Cancer Reports, Volume 9, Issue 6, June 2026.ABSTRACT Introduction Systemic cervical cancer management continues to be challenging. Numerous chemotherapies have been approved, but predicting response is difficult due to the lack of biomarkers. Here, we analyze the genetic and protein profiles of 20 cervical cancer cell lines (CCCLs) and explore their correlation with drug response patterns to ...
Suzy Scholl +10 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 6, June 2026.1. Lactate‐derived histone lactylation links glycolytic reprogramming to epigenetic regulation in female reproductive diseases. 2. In endometriosis, lactylation may promote inflammatory remodelling, immune dysregulation and ferroptosis resistance. 3. In PCOS, lactylation connects metabolic disturbance to granulosa‐cell dysfunction and hyperandrogenism.
Jiajun Qiao +5 more
wiley +1 more source