Results 101 to 110 of about 39,114 (250)

An An accurate molecular method to sex elephants using PCR amplification of Amelogenin gene

open access: yesPachyderm, 2020
The use of molecular methods to identify the sex of elephants from non-invasive samples is essential for studies of population dynamics and population genetics.
George Lohay
doaj   +1 more source

Sex-biased chromatin and regulatory cross-talk between sex chromosomes, autosomes, and mitochondria [PDF]

open access: yes, 2014
Several autoimmune and neurological diseases exhibit a sex bias, but discerning the causes and mechanisms of these biases has been challenging. Sex differences begin to manifest themselves in early embryonic development, and gonadal differentiation ...
Lemos, Bernardo, Silkaitis, Katherine
core   +1 more source

Primary sex determination of placental mammals: a modelling study uncovers dynamical developmental constraints in the formation of Sertoli and granulosa cells [PDF]

open access: yes, 2016
Primary sex determination in placental mammals is a very well studied developmental process. Here, we aim to investigate the currently established scenario and to assess its adequacy to fully recover the observed phenotypes, in the wild type and ...
Chaouiya, Claudine, Sánchez, Lucas
core   +2 more sources

Telomere protein complexes and their role in lymphoid malignancies [PDF]

open access: yes, 2017
Telomeres are highly regulated and dynamic complexes that protect the genomic DNA and prevent the end of linear chromosomes from being misrecognized as a broken DNA.
Dos Santos, Patricia Carolina   +2 more
core  

Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease. [PDF]

open access: yes, 2019
Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer's disease (AD).
Balaraman, Yokesh   +7 more
core   +3 more sources

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination.

open access: yesPLoS Biology, 2006
The genes encoding members of the wingless-related MMTV integration site (WNT) and fibroblast growth factor (FGF) families coordinate growth, morphogenesis, and differentiation in many fields of cells during development.
Yuna Kim   +9 more
doaj   +1 more source

MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen   +4 more
wiley   +1 more source

Sex-Dependent Gene Expression in Human Pluripotent Stem Cells

open access: yesCell Reports, 2014
Males and females have a variety of sexually dimorphic traits, most of which result from hormonal differences. However, differences between male and female embryos initiate very early in development, before hormonal influence begins, suggesting the ...
Daniel Ronen, Nissim Benvenisty
doaj   +1 more source

"Sexual differentiation: From genes to gender" [PDF]

open access: yes, 1998
Amy Wisniewski is Assistant Professor of Biology at Drake University, Des Moines, Iowa. She can be contacted at amy.wisniewski@drake.eduA person's sex can be considered across various levels.
Migeon, Claude J., Wisniewski, Amy B.
core   +2 more sources

Home - About - Disclaimer - Privacy