Results 71 to 80 of about 175,117 (235)

Genome-wide association studies of seven agronomic traits under two sowing conditions in bread wheat

BMC Plant Biology, 2019
Background Wheat is a cool seasoned crop requiring low temperature during grain filling duration and therefore increased temperature causes significant yield reduction.
Muhammad Jamil, Aamir Ali, Alvina Gul, Abdul Ghafoor, Abdul Aziz Napar, Amir M. H. Ibrahim, Naima Huma Naveed, Nasim Ahmad Yasin, Abdul Mujeeb-Kazi   +8 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Marker-assisted backcrossing for introgression of the saltol locus conferring salt stress tolerance in rice. [PE0856] [PDF]

, 2020
Soil salinization represents a threat for rice cultivation. The H2020 project NEURICE (New Commercial EUropean Rice) aimed at identifying and introducing genetic variation for salt tolerance in European rice germplasm, mainly by exploiting the positive ...
Brottier, Laurent, Canella, Marco, Cattivelli, Luigi, Cavallaro, Viviana, Courtois, Brigitte, Finocchiaro, Franca, Frouin, Julien, Gennaro, Massimo, Maré, Caterina, Monaco, Stefano, Samper, Patrick, Tacconi, Gianni, Tondelli, Alessandro, Valè, Giampiero, Zampieri, Elisa   +14 more
core  

Characterization of genome-wide SNPs for the water flea Daphnia pulicaria generated by genotyping-by-sequencing (GBS) [PDF]

, 2016
The keystone aquatic herbivore Daphnia has been studied for more than 150 years in the context of evolution, ecology and ecotoxicology. Although it is rapidly becoming an emergent model for environmental and population genomics, there have been limited ...
Chaturvedi, Anurag, De Meester, Luc, Muñoz, Joaquín, Weider, L.J.   +3 more
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Genotyping-by-sequencing (GBS): a novel, efficient and cost-effective genotyping method for cattle using next-generation sequencing. [PDF]

PLoS ONE, 2013
High-throughput genotyping methods have increased the analytical power to study complex traits but high cost has remained a barrier for large scale use in animal improvement. We have adapted genotyping-by-sequencing (GBS) used in plants for genotyping 47
Marcos De Donato, Sunday O Peters, Sharon E Mitchell, Tanveer Hussain, Ikhide G Imumorin   +4 more
doaj   +1 more source

NGS-based genotyping, high-throughput phenotyping and genome-wide association studies laid the foundations for next-generation breeding in horticultural crops [PDF]

, 2017
Demographic trends and changes to climate require a more efficient use of plant genetic resources in breeding programs. Indeed, the release of high-yielding varieties has resulted in crop genetic erosion and loss of diversity.
D'Agostino, Nunzio, Tripodi, Pasquale
core   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Genome-wide association study identified candidate genes controlling continuous storage root formation and bulking in hexaploid sweetpotato

BMC Plant Biology, 2020
Background Continuous storage root formation and bulking (CSRFAB) in sweetpotato is an important trait from agronomic and biological perspectives. Information about the molecular mechanisms underlying CSRFAB traits is lacking.
Astère Bararyenya, Bode A. Olukolu, Phinehas Tukamuhabwa, Wolfgang J. Grüneberg, Wellington Ekaya, Jan Low, Mildred Ochwo-Ssemakula, Thomas L. Odong, Herbert Talwana, Arfang Badji, Martina Kyalo, Yao Nasser, Dorcus Gemenet, Mercy Kitavi, Robert O. M. Mwanga   +14 more
doaj   +1 more source

An Ultra-High-Density, Transcript-Based, Genetic Map of Lettuce. [PDF]

, 2013
We have generated an ultra-high-density genetic map for lettuce, an economically important member of the Compositae, consisting of 12,842 unigenes (13,943 markers) mapped in 3696 genetic bins distributed over nine chromosomal linkage groups.
Ashrafi, Hamid, Bowers, John, Hill, Theresa, Kozik, Alexander, Michelmore, Richard W, Stoffel, Kevin, Truco, Maria José, Van Deynze, Allen, van Leeuwen, Hans, Wo, Sebastian Reyes Chin, Xu, Huaqin   +10 more
core   +1 more source