Results 91 to 100 of about 58,027,105 (302)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Utilization of Genotyping-by-Sequencing (GBS) for Rice Pre-Breeding and Improvement: A Review

, 2022
Molecular markers play a crucial role in the improvement of rice. To benefit from these markers, genotyping is carried out to identify the differences at a specific position in the genome of individuals.
Doi, Kazuyuki, Justine Kipruto Kitony, Reyes, Vincent Pamugas, Nishiuchi, Shunsaku, Vincent Pamugas Reyes, Kitony, Justine Kipruto, Kazuyuki Doi, Makihara, Daigo, Shunsaku Nishiuchi, Daigo Makihara   +9 more
core   +1 more source

Genotyping-by-Sequencing (GBS) of large amphibian genomes: a comparative study of two non-model species endemic to Italy: supplementary material

, 2019
Next Generation Sequencing (NGS) and related technologies have revolutionized the field of conservation and population genetics, providing novel tools and the capacity to discover thousands of new Single Nucleotide Polymorphisms (SNPs) for the analysis ...
Pezaro, Nadav, Buono, Vincenzo, CSIC - National Museum of Natural Sciences, Davoli, Francesca, Vieites, David R., University of Haifa, Rovelli, Valentina, University of the Basque Country, Fondazione Bioparco di Roma, Vignoli, Leonardo, Section of Biology and Environmental Science, Randi, Ettore, Department of Chemistry and Bioscience, Roma Tre University, Italian Institute for Environmental Protection and Research, The Faculty of Engineering and Science, Ruiz-Gonz?lez, Aritz, Aalborg University, MacAle, Daniele, David R. Vieites (546308), Daniele Macale (6017183), Aritz Ruiz-González (645630), Francesca Davoli (6017188), Valentina Rovelli (6017179), Ettore Randi (42572), Leonardo Vignoli (6017181), Nadav Pezaro (6017191), Vincenzo Buono (6017185)   +27 more
core   +2 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Evaluation of Off-Type Grasses in Hybrid Bermudagrass (Cynodon dactylon (L.) Pers. x C. transvaalensis Burtt-Davy) Putting Greens Using Genotyping-by-Sequencing

, 2016
The poster summarizes a collaborative project between the University of Tennessee and the University of Georgia.  Genotyping-by-sequencing analysis was performed to determine the genetic variation among ultradwarf bermudagrass cultivars and off-type ...
Meg Staton (654692), Robert Trigiano (3313572), Brian Schwartz (767427), Eric Reasor (3235254), Thomas Lane (3337914), Jim Brosnan (717055), Phil Wadl (3337911)   +6 more
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Genotyping-by-Sequencing application in Chinook Salmon

, 2016
Genomics and DNA sequencing technologies are rapidly advancing to the point where they can be cost effectively applied within aquaculture breeding programmes.
Hayley Baird (8845760), Shannon Clarke (3504989), Rachael Ashby (15393782), Jane Symonds (3577784), Jon Bailey (3695284), Mark Preece (15394256)   +5 more
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Comparison of relatedness from SNP chips and genotyping-by-sequencing

, 2017
Estimates of genomic relatedness derived from either SNP chip (two different densities) or genotyping-by-sequencing (GBS) resources were compared in a group of 95 sheep.
Ken Dodds (3501542), Rudiger Brauning (47247), Shannon Clarke (3504989), John McEwan (45371), Tracey Van Stijn (10380614)   +4 more
core  

Analysis methods for low-depth genotyping-by-sequencing data

, 2020
Outline -- Genotyping-By-Sequencing -- QC / filtering -- Relatedness & Parentage -- Allele sampling models -- Population Genetics -- Hardy-Weinberg -- FST -- Student’s ...
Ken Dodds (3501542)
core