Results 101 to 110 of about 58,027,105 (302)

Quantitative Genetic Mapping and Genome Assembly in the Lesser Wax Moth Achroia grisella

G3: Genes, Genomes, Genetics, 2019
Specific characteristics of the male Achroia grisella acoustic mating signal determine a male’s attractiveness toward females. These features are genetically variable in populations, and mapping experiments have been used to identify loci contributing to
Boryana S. Koseva, Jennifer L. Hackett, Yihong Zhou, Bethany R. Harris, John K. Kelly, Michael D. Greenfield, Jennifer M. Gleason, Stuart J. Macdonald   +7 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Population genetics and phylogeographic history of the insular lizard Podarcis lilfordi (Gunther, 1874) from the Balearic Islands based on genome‐wide polymorphic data

Ecology and Evolution
Islands provide a great system to explore the processes that maintain genetic diversity and promote local adaptation. We explored the genomic diversity of the Balearic lizard Podarcis lilfordi, an endemic species characterized by numerous small insular ...
Katherin Otalora, Joan Lluís Riera, Giacomo Tavecchia, Andreu Rotger, José Manuel Igual, Jean‐Remi Paul Trotta, Laura Baldo   +6 more
doaj   +1 more source

HLA genotyping by next-generation sequencing of complementary DNA

BMC Genomics, 2017
Background Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region.
Hidenobu Segawa, Yoji Kukita, Kikuya Kato   +2 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

Genetic Epidemiology, 2010
AbstractGenome‐wide association studies (GWAS) can identify common alleles that contribute to complex disease susceptibility. Despite the large number of SNPs assessed in each study, the effects of most common SNPs must be evaluated indirectly using either genotyped markers or haplotypes thereof as proxies.
Li, Yun, Willer, Cristen J., Ding, Jun, Scheet, Paul, Abecasis, Gonçalo R.   +4 more
openaire   +4 more sources

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

An investigation of allele sampling models for genotyping-by-sequencing

, 2018
Genotyping-by-sequencing (GBS) produces data suitable for genomic analysis such as genomic selection or parentage analysis. Analyses are improved when models which incorporate facets of the genotyping process are taken into account, for example the read ...
Ken Dodds (3501542), Rudiger Brauning (47247), Shannon Clarke (3504989), John McEwan (45371)   +3 more
core  

Genotyping-by-sequencing data of wheat lines grown in 2017 preliminary yield trials in the Nebraska small grains breeding program

, 2020
This study comprises genotyping-by-sequencing data of 273 wheat (Triticum aestivum) lines grown in 2017 preliminary yield trials (F3:6) in the Nebraska small grains breeding program.
P. Stephen Baenziger (436862), University of Nebraska - Lincoln (17856923)   +1 more
core  

Population Genomics Study on Sabah Weedy Rice Using Genotyping-by-Sequencing (GBS)

, 2020
This thesis examined the evolutionary origin of Sabah weedy rice by assessing its genetic diversity and population structure using genotyping-by-sequencing method.
RUPINI YESUDASAN (8230431)
core   +1 more source